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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
KRT17
Full Name:
Keratin, type I cytoskeletal 17
Alias:
39.1; CK 17; CK17; Cytokeratin 17; K1C17; Keratin 17; PC; PC2; PCHC1
Type:
Cytoskeletal protein
Mass (Da):
48106
Number AA:
432
UniProt ID:
Q04695
International Prot ID:
IPI00450768
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005882
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0005200
PhosphoSite+
KinaseNET
Biological Process:
GO:0008544
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T9
T
T
S
I
R
Q
F
T
S
S
S
S
I
K
G
Site 2
S10
T
S
I
R
Q
F
T
S
S
S
S
I
K
G
S
Site 3
S11
S
I
R
Q
F
T
S
S
S
S
I
K
G
S
S
Site 4
S12
I
R
Q
F
T
S
S
S
S
I
K
G
S
S
G
Site 5
S13
R
Q
F
T
S
S
S
S
I
K
G
S
S
G
L
Site 6
S17
S
S
S
S
I
K
G
S
S
G
L
G
G
G
S
Site 7
S18
S
S
S
I
K
G
S
S
G
L
G
G
G
S
S
Site 8
S24
S
S
G
L
G
G
G
S
S
R
T
S
C
R
L
Site 9
S25
S
G
L
G
G
G
S
S
R
T
S
C
R
L
S
Site 10
T27
L
G
G
G
S
S
R
T
S
C
R
L
S
G
G
Site 11
S28
G
G
G
S
S
R
T
S
C
R
L
S
G
G
L
Site 12
S32
S
R
T
S
C
R
L
S
G
G
L
G
A
G
S
Site 13
S39
S
G
G
L
G
A
G
S
C
R
L
G
S
A
G
Site 14
S44
A
G
S
C
R
L
G
S
A
G
G
L
G
S
T
Site 15
S50
G
S
A
G
G
L
G
S
T
L
G
G
S
S
Y
Site 16
T51
S
A
G
G
L
G
S
T
L
G
G
S
S
Y
S
Site 17
S55
L
G
S
T
L
G
G
S
S
Y
S
S
C
Y
S
Site 18
S56
G
S
T
L
G
G
S
S
Y
S
S
C
Y
S
F
Site 19
Y57
S
T
L
G
G
S
S
Y
S
S
C
Y
S
F
G
Site 20
S58
T
L
G
G
S
S
Y
S
S
C
Y
S
F
G
S
Site 21
S59
L
G
G
S
S
Y
S
S
C
Y
S
F
G
S
G
Site 22
Y61
G
S
S
Y
S
S
C
Y
S
F
G
S
G
G
G
Site 23
S62
S
S
Y
S
S
C
Y
S
F
G
S
G
G
G
Y
Site 24
S65
S
S
C
Y
S
F
G
S
G
G
G
Y
G
S
S
Site 25
Y69
S
F
G
S
G
G
G
Y
G
S
S
F
G
G
V
Site 26
S71
G
S
G
G
G
Y
G
S
S
F
G
G
V
D
G
Site 27
S72
S
G
G
G
Y
G
S
S
F
G
G
V
D
G
L
Site 28
S97
N
L
N
D
R
L
A
S
Y
L
D
K
V
R
A
Site 29
Y98
L
N
D
R
L
A
S
Y
L
D
K
V
R
A
L
Site 30
T110
R
A
L
E
E
A
N
T
E
L
E
V
K
I
R
Site 31
Y120
E
V
K
I
R
D
W
Y
Q
R
Q
A
P
G
P
Site 32
Y131
A
P
G
P
A
R
D
Y
S
Q
Y
Y
R
T
I
Site 33
S132
P
G
P
A
R
D
Y
S
Q
Y
Y
R
T
I
E
Site 34
Y134
P
A
R
D
Y
S
Q
Y
Y
R
T
I
E
E
L
Site 35
Y135
A
R
D
Y
S
Q
Y
Y
R
T
I
E
E
L
Q
Site 36
T171
L
A
A
D
D
F
R
T
K
F
E
T
E
Q
A
Site 37
T175
D
F
R
T
K
F
E
T
E
Q
A
L
R
L
S
Site 38
S182
T
E
Q
A
L
R
L
S
V
E
A
D
I
N
G
Site 39
T198
R
R
V
L
D
E
L
T
L
A
R
A
D
L
E
Site 40
Y217
N
L
K
E
E
L
A
Y
L
K
K
N
H
E
E
Site 41
S250
A
A
P
G
V
D
L
S
R
I
L
N
E
M
R
Site 42
Y260
L
N
E
M
R
D
Q
Y
E
K
M
A
E
K
N
Site 43
S277
D
A
E
D
W
F
F
S
K
T
E
E
L
N
R
Site 44
T279
E
D
W
F
F
S
K
T
E
E
L
N
R
E
V
Site 45
T288
E
L
N
R
E
V
A
T
N
S
E
L
V
Q
S
Site 46
S290
N
R
E
V
A
T
N
S
E
L
V
Q
S
G
K
Site 47
S295
T
N
S
E
L
V
Q
S
G
K
S
E
I
S
E
Site 48
S298
E
L
V
Q
S
G
K
S
E
I
S
E
L
R
R
Site 49
S301
Q
S
G
K
S
E
I
S
E
L
R
R
T
M
Q
Site 50
T306
E
I
S
E
L
R
R
T
M
Q
A
L
E
I
E
Site 51
S319
I
E
L
Q
S
Q
L
S
M
K
A
S
L
E
G
Site 52
S323
S
Q
L
S
M
K
A
S
L
E
G
N
L
A
E
Site 53
Y335
L
A
E
T
E
N
R
Y
C
V
Q
L
S
Q
I
Site 54
S348
Q
I
Q
G
L
I
G
S
V
E
E
Q
L
A
Q
Site 55
Y367
M
E
Q
Q
N
Q
E
Y
K
I
L
L
D
V
K
Site 56
T375
K
I
L
L
D
V
K
T
R
L
E
Q
E
I
A
Site 57
T383
R
L
E
Q
E
I
A
T
Y
R
R
L
L
E
G
Site 58
Y384
L
E
Q
E
I
A
T
Y
R
R
L
L
E
G
E
Site 59
T396
E
G
E
D
A
H
L
T
Q
Y
K
K
E
P
V
Site 60
Y398
E
D
A
H
L
T
Q
Y
K
K
E
P
V
T
T
Site 61
T404
Q
Y
K
K
E
P
V
T
T
R
Q
V
R
T
I
Site 62
T405
Y
K
K
E
P
V
T
T
R
Q
V
R
T
I
V
Site 63
S422
V
Q
D
G
K
V
I
S
S
R
E
Q
V
H
Q
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation