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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
REL
Full Name:
Proto-oncogene c-Rel
Alias:
Type:
Nucleus protein
Mass (Da):
68520
Number AA:
619
UniProt ID:
Q04864
International Prot ID:
IPI00029773
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0003700
PhosphoSite+
KinaseNET
Biological Process:
GO:0043123
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y6
_
_
M
A
S
G
A
Y
N
P
Y
I
E
I
I
Site 2
Y25
Q
R
G
M
R
F
R
Y
K
C
E
G
R
S
A
Site 3
T41
S
I
P
G
E
H
S
T
D
N
N
R
T
Y
P
Site 4
Y47
S
T
D
N
N
R
T
Y
P
S
I
Q
I
M
N
Site 5
Y55
P
S
I
Q
I
M
N
Y
Y
G
K
G
K
V
R
Site 6
Y56
S
I
Q
I
M
N
Y
Y
G
K
G
K
V
R
I
Site 7
T64
G
K
G
K
V
R
I
T
L
V
T
K
N
D
P
Site 8
Y72
L
V
T
K
N
D
P
Y
K
P
H
P
H
D
L
Site 9
Y88
G
K
D
C
R
D
G
Y
Y
E
A
E
F
G
Q
Site 10
Y89
K
D
C
R
D
G
Y
Y
E
A
E
F
G
Q
E
Site 11
T164
P
D
E
H
G
N
L
T
T
A
L
P
P
V
V
Site 12
Y176
P
V
V
S
N
P
I
Y
D
N
R
A
P
N
T
Site 13
S197
R
V
N
K
N
C
G
S
V
R
G
G
D
E
I
Site 14
S232
W
E
A
K
G
I
F
S
Q
A
D
V
H
R
Q
Site 15
T246
Q
V
A
I
V
F
K
T
P
P
Y
C
K
A
I
Site 16
T258
K
A
I
T
E
P
V
T
V
K
M
Q
L
R
R
Site 17
S267
K
M
Q
L
R
R
P
S
D
Q
E
V
S
E
S
Site 18
S274
S
D
Q
E
V
S
E
S
M
D
F
R
Y
L
P
Site 19
Y279
S
E
S
M
D
F
R
Y
L
P
D
E
K
D
T
Site 20
Y287
L
P
D
E
K
D
T
Y
G
N
K
A
K
K
Q
Site 21
S325
D
G
L
E
L
L
T
S
G
D
P
P
T
L
A
Site 22
T330
L
T
S
G
D
P
P
T
L
A
S
Q
S
A
G
Site 23
S333
G
D
P
P
T
L
A
S
Q
S
A
G
I
T
V
Site 24
T339
A
S
Q
S
A
G
I
T
V
N
F
P
E
R
P
Site 25
S353
P
R
P
G
L
L
G
S
I
G
E
G
R
Y
F
Site 26
Y359
G
S
I
G
E
G
R
Y
F
K
K
E
P
N
L
Site 27
S382
E
M
P
T
G
V
S
S
Q
A
E
S
Y
Y
P
Site 28
S386
G
V
S
S
Q
A
E
S
Y
Y
P
S
P
G
P
Site 29
Y387
V
S
S
Q
A
E
S
Y
Y
P
S
P
G
P
I
Site 30
Y388
S
S
Q
A
E
S
Y
Y
P
S
P
G
P
I
S
Site 31
S390
Q
A
E
S
Y
Y
P
S
P
G
P
I
S
S
G
Site 32
S395
Y
P
S
P
G
P
I
S
S
G
L
S
H
H
A
Site 33
S396
P
S
P
G
P
I
S
S
G
L
S
H
H
A
S
Site 34
S399
G
P
I
S
S
G
L
S
H
H
A
S
M
A
P
Site 35
S403
S
G
L
S
H
H
A
S
M
A
P
L
P
S
S
Site 36
S410
S
M
A
P
L
P
S
S
S
W
S
S
V
A
H
Site 37
S411
M
A
P
L
P
S
S
S
W
S
S
V
A
H
P
Site 38
S413
P
L
P
S
S
S
W
S
S
V
A
H
P
T
P
Site 39
S414
L
P
S
S
S
W
S
S
V
A
H
P
T
P
R
Site 40
T419
W
S
S
V
A
H
P
T
P
R
S
G
N
T
N
Site 41
S422
V
A
H
P
T
P
R
S
G
N
T
N
P
L
S
Site 42
T425
P
T
P
R
S
G
N
T
N
P
L
S
S
F
S
Site 43
S429
S
G
N
T
N
P
L
S
S
F
S
T
R
T
L
Site 44
S430
G
N
T
N
P
L
S
S
F
S
T
R
T
L
P
Site 45
S432
T
N
P
L
S
S
F
S
T
R
T
L
P
S
N
Site 46
T433
N
P
L
S
S
F
S
T
R
T
L
P
S
N
S
Site 47
T435
L
S
S
F
S
T
R
T
L
P
S
N
S
Q
G
Site 48
S440
T
R
T
L
P
S
N
S
Q
G
I
P
P
F
L
Site 49
S479
M
E
A
S
S
M
P
S
A
D
L
Y
G
I
S
Site 50
Y483
S
M
P
S
A
D
L
Y
G
I
S
D
P
N
M
Site 51
S486
S
A
D
L
Y
G
I
S
D
P
N
M
L
S
N
Site 52
S492
I
S
D
P
N
M
L
S
N
C
S
V
N
M
M
Site 53
T500
N
C
S
V
N
M
M
T
T
S
S
D
S
M
G
Site 54
T501
C
S
V
N
M
M
T
T
S
S
D
S
M
G
E
Site 55
S503
V
N
M
M
T
T
S
S
D
S
M
G
E
T
D
Site 56
S505
M
M
T
T
S
S
D
S
M
G
E
T
D
N
P
Site 57
T509
S
S
D
S
M
G
E
T
D
N
P
R
L
L
S
Site 58
S516
T
D
N
P
R
L
L
S
M
N
L
E
N
P
S
Site 59
S523
S
M
N
L
E
N
P
S
C
N
S
V
L
D
P
Site 60
S526
L
E
N
P
S
C
N
S
V
L
D
P
R
D
L
Site 61
S540
L
R
Q
L
H
Q
M
S
S
S
S
M
S
A
G
Site 62
S541
R
Q
L
H
Q
M
S
S
S
S
M
S
A
G
A
Site 63
S542
Q
L
H
Q
M
S
S
S
S
M
S
A
G
A
N
Site 64
S543
L
H
Q
M
S
S
S
S
M
S
A
G
A
N
S
Site 65
S545
Q
M
S
S
S
S
M
S
A
G
A
N
S
N
T
Site 66
T552
S
A
G
A
N
S
N
T
T
V
F
V
S
Q
S
Site 67
T553
A
G
A
N
S
N
T
T
V
F
V
S
Q
S
D
Site 68
S557
S
N
T
T
V
F
V
S
Q
S
D
A
F
E
G
Site 69
S559
T
T
V
F
V
S
Q
S
D
A
F
E
G
S
D
Site 70
S565
Q
S
D
A
F
E
G
S
D
F
S
C
A
D
N
Site 71
S568
A
F
E
G
S
D
F
S
C
A
D
N
S
M
I
Site 72
S573
D
F
S
C
A
D
N
S
M
I
N
E
S
G
P
Site 73
S578
D
N
S
M
I
N
E
S
G
P
S
N
S
T
N
Site 74
S581
M
I
N
E
S
G
P
S
N
S
T
N
P
N
S
Site 75
S583
N
E
S
G
P
S
N
S
T
N
P
N
S
H
G
Site 76
T584
E
S
G
P
S
N
S
T
N
P
N
S
H
G
F
Site 77
S588
S
N
S
T
N
P
N
S
H
G
F
V
Q
D
S
Site 78
S595
S
H
G
F
V
Q
D
S
Q
Y
S
G
I
G
S
Site 79
Y597
G
F
V
Q
D
S
Q
Y
S
G
I
G
S
M
Q
Site 80
S602
S
Q
Y
S
G
I
G
S
M
Q
N
E
Q
L
S
Site 81
S609
S
M
Q
N
E
Q
L
S
D
S
F
P
Y
E
F
Site 82
S611
Q
N
E
Q
L
S
D
S
F
P
Y
E
F
F
Q
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation