PhosphoNET

           
Protein Info 
   
Short Name:  Ron
Full Name:  Macrophage-stimulating protein receptor
Alias:  CD136; CD136 antigen; CDW136; C-met-related tyrosine kinase; EC 2.7.10.1K; Kinase RON; Macrophage stimulating 1 receptor; Macrophage-stimulating protein receptor precursor; MSP receptor; MST1R; P185-Ron; PTK8; RON; ST; Stem cell-derived tyrosine kinase; STK
Type:  EC 2.7.10.1; Receptor tyrosine kinase; TK group; Met family
Mass (Da):  152227
Number AA:  1400
UniProt ID:  Q04912
International Prot ID:  IPI00030273
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005887     Uniprot OncoNet
Molecular Function:  GO:0005524  GO:0005011  GO:0005515 PhosphoSite+ KinaseNET
Biological Process:  GO:0006928  GO:0006952  GO:0007275 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S215AGSFSPRSVSIRRLK
Site 2S226RRLKADASGFAPGFV
Site 3S236APGFVALSVLPKHLV
Site 4S998PNLNDLASLDQTAGA
Site 5T1002DLASLDQTAGATPLP
Site 6S1013TPLPILYSGSDYRSG
Site 7S1015LPILYSGSDYRSGLA
Site 8Y1017ILYSGSDYRSGLALP
Site 9S1019YSGSDYRSGLALPAI
Site 10S1039TTCVHGASFSDSEDE
Site 11S1041CVHGASFSDSEDESC
Site 12S1043HGASFSDSEDESCVP
Site 13S1047FSDSEDESCVPLLRK
Site 14S1056VPLLRKESIQLRDLD
Site 15T1082IPHERVVTHSDRVIG
Site 16S1084HERVVTHSDRVIGKG
Site 17Y1097KGHFGVVYHGEYIDQ
Site 18Y1101GVVYHGEYIDQAQNR
Site 19S1115RIQCAIKSLSRITEM
Site 20S1117QCAIKSLSRITEMQQ
Site 21T1120IKSLSRITEMQQVEA
Site 22S1175DLLQFIRSPQRNPTV
Site 23T1181RSPQRNPTVKDLISF
Site 24Y1198QVARGMEYLAEQKFV
Site 25S1219RNCMLDESFTVKVAD
Site 26Y1238RDILDREYYSVQQHR
Site 27Y1239DILDREYYSVQQHRH
Site 28S1240ILDREYYSVQQHRHA
Site 29T1261MALESLQTYRFTTKS
Site 30Y1262ALESLQTYRFTTKSD
Site 31T1265SLQTYRFTTKSDVWS
Site 32T1266LQTYRFTTKSDVWSF
Site 33Y1288LTRGAPPYRHIDPFD
Site 34T1297HIDPFDLTHFLAQGR
Site 35Y1311RRLPQPEYCPDSLYQ
Site 36Y1317EYCPDSLYQVMQQCW
Site 37Y1353SALLGDHYVQLPATY
Site 38T1359HYVQLPATYMNLGPS
Site 39Y1360YVQLPATYMNLGPST
Site 40S1368MNLGPSTSHEMNVRP
Site 41S1381RPEQPQFSPMPGNVR
Site 42S1394VRRPRPLSEPPRPT_
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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