KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
GAD2
Full Name:
Glutamate decarboxylase 2
Alias:
65 kDa glutamic acid decarboxylase;Glutamate decarboxylase 65 kDa isoform
Type:
Mass (Da):
65411
Number AA:
585
UniProt ID:
Q05329
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Glutamated decarboxylase 2 (E476-I484, human) peptide - Powder PE-01AAP80#http://www.kinexusproducts.ca/ProductInfo_Peptide.aspx?Product_Number=PE-01AAP80#Glutamate decarboxylase 2 (F557-A565, human) peptide - Powder PE-01ABA80#http://www.kinexusproducts.ca/ProductInfo_Peptide.aspx?Product_Number=PE-01ABA80#Glutamate decarboxylase 2 (R558-A565, human) peptide - Powder PE-01ABB90#http://www.kinexusproducts.ca/ProductInfo_Peptide.aspx?Product_Number=PE-01ABB90#Glutamate decarboxylase 2 (L475-I484, human) peptide - Powder PE-01ANK95#http://www.kinexusproducts.ca/ProductInfo_Peptide.aspx?Product_Number=PE-01ANK95
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S3
_
_
_
_
_
M
A
S
P
G
S
G
F
W
S
Site 2
S6
_
_
M
A
S
P
G
S
G
F
W
S
F
G
S
Site 3
S10
S
P
G
S
G
F
W
S
F
G
S
E
D
G
S
Site 4
S13
S
G
F
W
S
F
G
S
E
D
G
S
G
D
S
Site 5
S17
S
F
G
S
E
D
G
S
G
D
S
E
N
P
G
Site 6
S20
S
E
D
G
S
G
D
S
E
N
P
G
T
A
R
Site 7
T25
G
D
S
E
N
P
G
T
A
R
A
W
C
Q
V
Site 8
Y49
N
K
L
C
A
L
L
Y
G
D
A
E
K
P
A
Site 9
S61
K
P
A
E
S
G
G
S
Q
P
P
R
A
A
A
Site 10
Y89
C
S
K
V
D
V
N
Y
A
F
L
H
A
T
D
Site 11
T107
A
C
D
G
E
R
P
T
L
A
F
L
Q
D
V
Site 12
S125
L
L
Q
Y
V
V
K
S
F
D
R
S
T
K
V
Site 13
S129
V
V
K
S
F
D
R
S
T
K
V
I
D
F
H
Site 14
T130
V
K
S
F
D
R
S
T
K
V
I
D
F
H
Y
Site 15
Y137
T
K
V
I
D
F
H
Y
P
N
E
L
L
Q
E
Site 16
Y169
H
C
Q
T
T
L
K
Y
A
I
K
T
G
H
P
Site 17
Y178
I
K
T
G
H
P
R
Y
F
N
Q
L
S
T
G
Site 18
S183
P
R
Y
F
N
Q
L
S
T
G
L
D
M
V
G
Site 19
S240
G
S
G
D
G
I
F
S
P
G
G
A
I
S
N
Site 20
T277
L
P
R
L
I
A
F
T
S
E
H
S
H
F
S
Site 21
S278
P
R
L
I
A
F
T
S
E
H
S
H
F
S
L
Site 22
S284
T
S
E
H
S
H
F
S
L
K
K
G
A
A
A
Site 23
S313
E
R
G
K
M
I
P
S
D
L
E
R
R
I
L
Site 24
S382
R
K
H
K
W
K
L
S
G
V
E
R
A
N
S
Site 25
S389
S
G
V
E
R
A
N
S
V
T
W
N
P
H
K
Site 26
Y433
L
F
Q
Q
D
K
H
Y
D
L
S
Y
D
T
G
Site 27
Y437
D
K
H
Y
D
L
S
Y
D
T
G
D
K
A
L
Site 28
Y480
K
C
L
E
L
A
E
Y
L
Y
N
I
I
K
N
Site 29
Y482
L
E
L
A
E
Y
L
Y
N
I
I
K
N
R
E
Site 30
Y491
I
I
K
N
R
E
G
Y
E
M
V
F
D
G
K
Site 31
S524
E
D
N
E
E
R
M
S
R
L
S
K
V
A
P
Site 32
S527
E
E
R
M
S
R
L
S
K
V
A
P
V
I
K
Site 33
S546
E
Y
G
T
T
M
V
S
Y
Q
P
L
G
D
K
Site 34
Y547
Y
G
T
T
M
V
S
Y
Q
P
L
G
D
K
V
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation