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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SFRS11
Full Name:
Serine/arginine-rich splicing factor 11
Alias:
Arginine-rich 54 kDa nuclear protein; NET2; P54; SFR11; Splicing factor arginine/serine-rich 11; Splicing factor, arginine/serine-rich 11
Type:
RNA binding protein, RNA processing
Mass (Da):
53542
Number AA:
484
UniProt ID:
Q05519
International Prot ID:
IPI00464952
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
GO:0005730
GO:0043226
Uniprot
OncoNet
Molecular Function:
GO:0003723
GO:0000166
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0000398
GO:0008380
GO:0000398
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T5
_
_
_
M
S
N
T
T
V
V
P
S
T
A
G
Site 2
S9
S
N
T
T
V
V
P
S
T
A
G
P
G
P
S
Site 3
T10
N
T
T
V
V
P
S
T
A
G
P
G
P
S
G
Site 4
S16
S
T
A
G
P
G
P
S
G
G
P
G
G
G
G
Site 5
T32
G
G
G
G
G
G
G
T
E
V
I
Q
V
T
N
Site 6
T38
G
T
E
V
I
Q
V
T
N
V
S
P
S
A
S
Site 7
S41
V
I
Q
V
T
N
V
S
P
S
A
S
S
E
Q
Site 8
S43
Q
V
T
N
V
S
P
S
A
S
S
E
Q
M
R
Site 9
S45
T
N
V
S
P
S
A
S
S
E
Q
M
R
T
L
Site 10
T51
A
S
S
E
Q
M
R
T
L
F
G
F
L
G
K
Site 11
S70
R
L
F
P
P
D
D
S
P
L
P
V
S
S
R
Site 12
S75
D
D
S
P
L
P
V
S
S
R
V
C
F
V
K
Site 13
S88
V
K
F
H
D
P
D
S
A
V
V
A
Q
H
L
Site 14
T143
P
G
G
G
L
L
P
T
P
N
P
L
T
Q
I
Site 15
S179
L
P
G
A
N
L
N
S
Q
S
L
A
A
D
Q
Site 16
S192
D
Q
L
L
K
L
M
S
T
V
D
P
K
L
N
Site 17
T193
Q
L
L
K
L
M
S
T
V
D
P
K
L
N
H
Site 18
S207
H
V
A
A
G
L
V
S
P
S
L
K
S
D
T
Site 19
S209
A
A
G
L
V
S
P
S
L
K
S
D
T
S
S
Site 20
S212
L
V
S
P
S
L
K
S
D
T
S
S
K
E
I
Site 21
T214
S
P
S
L
K
S
D
T
S
S
K
E
I
E
E
Site 22
S215
P
S
L
K
S
D
T
S
S
K
E
I
E
E
A
Site 23
S216
S
L
K
S
D
T
S
S
K
E
I
E
E
A
M
Site 24
S231
K
R
V
R
E
A
Q
S
L
I
S
A
A
I
E
Site 25
S234
R
E
A
Q
S
L
I
S
A
A
I
E
P
D
K
Site 26
S249
K
E
E
K
R
R
H
S
R
S
R
S
R
S
R
Site 27
S251
E
K
R
R
H
S
R
S
R
S
R
S
R
R
R
Site 28
S253
R
R
H
S
R
S
R
S
R
S
R
R
R
R
T
Site 29
S255
H
S
R
S
R
S
R
S
R
R
R
R
T
P
S
Site 30
T260
S
R
S
R
R
R
R
T
P
S
S
S
R
H
R
Site 31
S262
S
R
R
R
R
T
P
S
S
S
R
H
R
R
S
Site 32
S263
R
R
R
R
T
P
S
S
S
R
H
R
R
S
R
Site 33
S264
R
R
R
T
P
S
S
S
R
H
R
R
S
R
S
Site 34
S269
S
S
S
R
H
R
R
S
R
S
R
S
R
R
R
Site 35
S271
S
R
H
R
R
S
R
S
R
S
R
R
R
S
H
Site 36
S273
H
R
R
S
R
S
R
S
R
R
R
S
H
S
K
Site 37
S277
R
S
R
S
R
R
R
S
H
S
K
S
R
S
R
Site 38
S279
R
S
R
R
R
S
H
S
K
S
R
S
R
R
R
Site 39
S281
R
R
R
S
H
S
K
S
R
S
R
R
R
S
K
Site 40
S283
R
S
H
S
K
S
R
S
R
R
R
S
K
S
P
Site 41
S287
K
S
R
S
R
R
R
S
K
S
P
R
R
R
R
Site 42
S289
R
S
R
R
R
S
K
S
P
R
R
R
R
S
H
Site 43
S295
K
S
P
R
R
R
R
S
H
S
R
E
R
G
R
Site 44
S297
P
R
R
R
R
S
H
S
R
E
R
G
R
R
S
Site 45
S304
S
R
E
R
G
R
R
S
R
S
T
S
K
T
R
Site 46
S306
E
R
G
R
R
S
R
S
T
S
K
T
R
D
K
Site 47
T307
R
G
R
R
S
R
S
T
S
K
T
R
D
K
K
Site 48
S308
G
R
R
S
R
S
T
S
K
T
R
D
K
K
K
Site 49
T310
R
S
R
S
T
S
K
T
R
D
K
K
K
E
D
Site 50
S323
E
D
K
E
K
K
R
S
K
T
P
P
K
S
Y
Site 51
T325
K
E
K
K
R
S
K
T
P
P
K
S
Y
S
T
Site 52
S329
R
S
K
T
P
P
K
S
Y
S
T
A
R
R
S
Site 53
S331
K
T
P
P
K
S
Y
S
T
A
R
R
S
R
S
Site 54
T332
T
P
P
K
S
Y
S
T
A
R
R
S
R
S
A
Site 55
S336
S
Y
S
T
A
R
R
S
R
S
A
S
R
E
R
Site 56
S338
S
T
A
R
R
S
R
S
A
S
R
E
R
R
R
Site 57
S340
A
R
R
S
R
S
A
S
R
E
R
R
R
R
R
Site 58
S348
R
E
R
R
R
R
R
S
R
S
G
T
R
S
P
Site 59
S350
R
R
R
R
R
S
R
S
G
T
R
S
P
K
K
Site 60
T352
R
R
R
S
R
S
G
T
R
S
P
K
K
P
R
Site 61
S354
R
S
R
S
G
T
R
S
P
K
K
P
R
S
P
Site 62
S360
R
S
P
K
K
P
R
S
P
K
R
K
L
S
R
Site 63
S366
R
S
P
K
R
K
L
S
R
S
P
S
P
R
R
Site 64
S368
P
K
R
K
L
S
R
S
P
S
P
R
R
H
K
Site 65
S370
R
K
L
S
R
S
P
S
P
R
R
H
K
K
E
Site 66
S394
S
R
D
E
R
E
R
S
T
S
K
K
K
K
S
Site 67
T395
R
D
E
R
E
R
S
T
S
K
K
K
K
S
K
Site 68
S396
D
E
R
E
R
S
T
S
K
K
K
K
S
K
D
Site 69
S401
S
T
S
K
K
K
K
S
K
D
K
E
K
D
R
Site 70
S412
E
K
D
R
E
R
K
S
E
S
D
K
D
V
K
Site 71
S414
D
R
E
R
K
S
E
S
D
K
D
V
K
Q
V
Site 72
Y425
V
K
Q
V
T
R
D
Y
D
E
E
E
Q
G
Y
Site 73
Y432
Y
D
E
E
E
Q
G
Y
D
S
E
K
E
K
K
Site 74
S434
E
E
E
Q
G
Y
D
S
E
K
E
K
K
E
E
Site 75
T447
E
E
K
K
P
I
E
T
G
S
P
K
T
K
E
Site 76
S449
K
K
P
I
E
T
G
S
P
K
T
K
E
C
S
Site 77
T452
I
E
T
G
S
P
K
T
K
E
C
S
V
E
K
Site 78
S456
S
P
K
T
K
E
C
S
V
E
K
G
T
G
D
Site 79
S464
V
E
K
G
T
G
D
S
L
R
E
S
K
V
N
Site 80
S468
T
G
D
S
L
R
E
S
K
V
N
G
D
D
H
Site 81
S483
H
E
E
D
M
D
M
S
D
_
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation