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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
EEF1A2
Full Name:
Elongation factor 1-alpha 2
Alias:
EEF1A-2; EEF1AL; EF12; EF1A2; EF-1-alpha-2; Elongation factor 1 A-2; Eukaryotic translation elongation factor 1 alpha 2; HS1; Statin S1; STN; STNL
Type:
Translation protein, initiation complex
Mass (Da):
50470
Number AA:
463
UniProt ID:
Q05639
International Prot ID:
IPI00396485
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
GO:0005737
GO:0005853
Uniprot
OncoNet
Molecular Function:
GO:0000166
GO:0003676
GO:0003746
PhosphoSite+
KinaseNET
Biological Process:
GO:0006412
GO:0006414
GO:0006916
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T6
_
_
M
G
K
E
K
T
H
I
N
I
V
V
I
Site 2
S18
V
V
I
G
H
V
D
S
G
K
S
T
T
T
G
Site 3
S21
G
H
V
D
S
G
K
S
T
T
T
G
H
L
I
Site 4
T22
H
V
D
S
G
K
S
T
T
T
G
H
L
I
Y
Site 5
T23
V
D
S
G
K
S
T
T
T
G
H
L
I
Y
K
Site 6
T24
D
S
G
K
S
T
T
T
G
H
L
I
Y
K
C
Site 7
Y29
T
T
T
G
H
L
I
Y
K
C
G
G
I
D
K
Site 8
T38
C
G
G
I
D
K
R
T
I
E
K
F
E
K
E
Site 9
Y56
M
G
K
G
S
F
K
Y
A
W
V
L
D
K
L
Site 10
T72
A
E
R
E
R
G
I
T
I
D
I
S
L
W
K
Site 11
S76
R
G
I
T
I
D
I
S
L
W
K
F
E
T
T
Site 12
Y85
W
K
F
E
T
T
K
Y
Y
I
T
I
I
D
A
Site 13
Y86
K
F
E
T
T
K
Y
Y
I
T
I
I
D
A
P
Site 14
T88
E
T
T
K
Y
Y
I
T
I
I
D
A
P
G
H
Site 15
T106
I
K
N
M
I
T
G
T
S
Q
A
D
C
A
V
Site 16
S128
G
E
F
E
A
G
I
S
K
N
G
Q
T
R
E
Site 17
T133
G
I
S
K
N
G
Q
T
R
E
H
A
L
L
A
Site 18
Y141
R
E
H
A
L
L
A
Y
T
L
G
V
K
Q
L
Site 19
T142
E
H
A
L
L
A
Y
T
L
G
V
K
Q
L
I
Site 20
S157
V
G
V
N
K
M
D
S
T
E
P
A
Y
S
E
Site 21
T158
G
V
N
K
M
D
S
T
E
P
A
Y
S
E
K
Site 22
S163
D
S
T
E
P
A
Y
S
E
K
R
Y
D
E
I
Site 23
Y167
P
A
Y
S
E
K
R
Y
D
E
I
V
K
E
V
Site 24
S175
D
E
I
V
K
E
V
S
A
Y
I
K
K
I
G
Site 25
Y177
I
V
K
E
V
S
A
Y
I
K
K
I
G
Y
N
Site 26
S224
E
R
K
E
G
N
A
S
G
V
S
L
L
E
A
Site 27
S227
E
G
N
A
S
G
V
S
L
L
E
A
L
D
T
Site 28
T234
S
L
L
E
A
L
D
T
I
L
P
P
T
R
P
Site 29
T242
I
L
P
P
T
R
P
T
D
K
P
L
R
L
P
Site 30
Y254
R
L
P
L
Q
D
V
Y
K
I
G
G
I
G
T
Site 31
T261
Y
K
I
G
G
I
G
T
V
P
V
G
R
V
E
Site 32
T287
F
A
P
V
N
I
T
T
E
V
K
S
V
E
M
Site 33
S291
N
I
T
T
E
V
K
S
V
E
M
H
H
E
A
Site 34
S300
E
M
H
H
E
A
L
S
E
A
L
P
G
D
N
Site 35
S316
G
F
N
V
K
N
V
S
V
K
D
I
R
R
G
Site 36
S329
R
G
N
V
C
G
D
S
K
S
D
P
P
Q
E
Site 37
S331
N
V
C
G
D
S
K
S
D
P
P
Q
E
A
A
Site 38
S342
Q
E
A
A
Q
F
T
S
Q
V
I
I
L
N
H
Site 39
S354
L
N
H
P
G
Q
I
S
A
G
Y
S
P
V
I
Site 40
Y357
P
G
Q
I
S
A
G
Y
S
P
V
I
D
C
H
Site 41
S358
G
Q
I
S
A
G
Y
S
P
V
I
D
C
H
T
Site 42
S383
K
E
K
I
D
R
R
S
G
K
K
L
E
D
N
Site 43
S393
K
L
E
D
N
P
K
S
L
K
S
G
D
A
A
Site 44
S414
G
K
P
M
C
V
E
S
F
S
Q
Y
P
P
L
Site 45
S416
P
M
C
V
E
S
F
S
Q
Y
P
P
L
G
R
Site 46
Y418
C
V
E
S
F
S
Q
Y
P
P
L
G
R
F
A
Site 47
T432
A
V
R
D
M
R
Q
T
V
A
V
G
V
I
K
Site 48
S454
G
A
G
K
V
T
K
S
A
Q
K
A
Q
K
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation