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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
Hepatocellular carcinoma protein HHCM
Full Name:
Hepatocellular carcinoma protein HHCM
Alias:
Type:
Mass (Da):
52151
Number AA:
467
UniProt ID:
Q05877
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T5
_
_
_
M
L
P
F
T
C
G
R
N
A
N
E
Site 2
S14
G
R
N
A
N
E
N
S
P
R
D
V
D
V
G
Site 3
S43
S
T
A
K
A
G
L
S
S
R
S
G
G
G
G
Site 4
S44
T
A
K
A
G
L
S
S
R
S
G
G
G
G
S
Site 5
S46
K
A
G
L
S
S
R
S
G
G
G
G
S
L
S
Site 6
S51
S
R
S
G
G
G
G
S
L
S
H
L
F
C
E
Site 7
S72
L
K
H
V
E
K
L
S
E
L
P
P
G
H
M
Site 8
S89
D
T
L
I
I
K
L
S
G
R
L
R
N
K
T
Site 9
T96
S
G
R
L
R
N
K
T
K
M
E
V
P
P
N
Site 10
T120
L
W
H
S
L
A
L
T
Q
G
S
P
H
S
R
Site 11
S123
S
L
A
L
T
Q
G
S
P
H
S
R
S
R
H
Site 12
S126
L
T
Q
G
S
P
H
S
R
S
R
H
Q
G
T
Site 13
S128
Q
G
S
P
H
S
R
S
R
H
Q
G
T
G
G
Site 14
T140
T
G
G
E
L
W
G
T
L
Q
A
Y
S
V
N
Site 15
T162
A
T
M
E
P
A
G
T
H
N
T
E
G
R
D
Site 16
S172
T
E
G
R
D
L
A
S
N
Q
I
S
C
D
S
Site 17
S176
D
L
A
S
N
Q
I
S
C
D
S
R
E
G
G
Site 18
S179
S
N
Q
I
S
C
D
S
R
E
G
G
V
K
A
Site 19
T199
S
T
S
S
H
V
M
T
P
E
G
R
R
G
R
Site 20
S215
C
E
H
R
D
I
M
S
R
S
L
L
T
R
C
Site 21
S217
H
R
D
I
M
S
R
S
L
L
T
R
C
P
K
Site 22
T220
I
M
S
R
S
L
L
T
R
C
P
K
E
E
S
Site 23
S227
T
R
C
P
K
E
E
S
Q
V
T
T
Q
H
Q
Site 24
T230
P
K
E
E
S
Q
V
T
T
Q
H
Q
R
N
C
Site 25
T231
K
E
E
S
Q
V
T
T
Q
H
Q
R
N
C
R
Site 26
S247
M
R
N
F
G
K
Q
S
I
V
L
S
V
K
P
Site 27
Y273
V
T
L
D
G
I
D
Y
E
E
P
G
E
G
I
Site 28
Y281
E
E
P
G
E
G
I
Y
L
H
R
D
V
R
V
Site 29
T300
K
H
H
E
A
L
K
T
E
L
M
W
K
P
Q
Site 30
S332
C
K
T
K
L
Q
H
S
P
Y
H
L
N
K
T
Site 31
Y334
T
K
L
Q
H
S
P
Y
H
L
N
K
T
Q
S
Site 32
T339
S
P
Y
H
L
N
K
T
Q
S
L
T
T
F
K
Site 33
S341
Y
H
L
N
K
T
Q
S
L
T
T
F
K
T
P
Site 34
T343
L
N
K
T
Q
S
L
T
T
F
K
T
P
R
T
Site 35
T347
Q
S
L
T
T
F
K
T
P
R
T
Q
S
K
I
Site 36
T350
T
T
F
K
T
P
R
T
Q
S
K
I
T
S
T
Site 37
S352
F
K
T
P
R
T
Q
S
K
I
T
S
T
K
N
Site 38
S356
R
T
Q
S
K
I
T
S
T
K
N
Q
E
N
L
Site 39
S371
N
E
Q
G
K
W
Q
S
V
A
A
S
A
E
M
Site 40
S375
K
W
Q
S
V
A
A
S
A
E
M
T
M
R
V
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation