KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
MBTD1
Full Name:
MBT domain-containing protein 1
Alias:
flj20055; flj42067; Sa49p01
Type:
Transcription regulation
Mass (Da):
70547
Number AA:
628
UniProt ID:
Q05BQ5
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0045449
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S7
_
M
F
D
G
Y
D
S
C
S
E
D
T
S
S
Site 2
S9
F
D
G
Y
D
S
C
S
E
D
T
S
S
S
S
Site 3
T12
Y
D
S
C
S
E
D
T
S
S
S
S
S
S
E
Site 4
S13
D
S
C
S
E
D
T
S
S
S
S
S
S
E
E
Site 5
S14
S
C
S
E
D
T
S
S
S
S
S
S
E
E
S
Site 6
S15
C
S
E
D
T
S
S
S
S
S
S
E
E
S
E
Site 7
S16
S
E
D
T
S
S
S
S
S
S
E
E
S
E
E
Site 8
S17
E
D
T
S
S
S
S
S
S
E
E
S
E
E
E
Site 9
S18
D
T
S
S
S
S
S
S
E
E
S
E
E
E
V
Site 10
S21
S
S
S
S
S
E
E
S
E
E
E
V
A
P
L
Site 11
Y42
I
K
N
N
G
Q
V
Y
T
Y
P
D
G
K
S
Site 12
Y44
N
N
G
Q
V
Y
T
Y
P
D
G
K
S
G
M
Site 13
Y67
V
G
V
R
D
A
F
Y
S
K
T
K
R
F
C
Site 14
S68
G
V
R
D
A
F
Y
S
K
T
K
R
F
C
S
Site 15
T70
R
D
A
F
Y
S
K
T
K
R
F
C
S
V
S
Site 16
S75
S
K
T
K
R
F
C
S
V
S
C
S
R
S
Y
Site 17
S77
T
K
R
F
C
S
V
S
C
S
R
S
Y
S
S
Site 18
S79
R
F
C
S
V
S
C
S
R
S
Y
S
S
N
S
Site 19
S81
C
S
V
S
C
S
R
S
Y
S
S
N
S
K
K
Site 20
Y82
S
V
S
C
S
R
S
Y
S
S
N
S
K
K
A
Site 21
S83
V
S
C
S
R
S
Y
S
S
N
S
K
K
A
S
Site 22
S84
S
C
S
R
S
Y
S
S
N
S
K
K
A
S
I
Site 23
S86
S
R
S
Y
S
S
N
S
K
K
A
S
I
L
A
Site 24
S90
S
S
N
S
K
K
A
S
I
L
A
R
L
Q
G
Site 25
S137
A
K
T
K
A
A
V
S
M
E
G
F
S
W
G
Site 26
Y146
E
G
F
S
W
G
N
Y
I
N
S
N
S
F
I
Site 27
T183
V
R
V
E
V
P
N
T
D
C
S
L
P
T
K
Site 28
T247
K
P
L
V
P
P
R
T
I
Q
H
K
Y
T
N
Site 29
Y252
P
R
T
I
Q
H
K
Y
T
N
W
K
A
F
L
Site 30
T268
K
R
L
T
G
A
K
T
L
P
P
D
F
S
Q
Site 31
S274
K
T
L
P
P
D
F
S
Q
K
V
S
E
S
M
Site 32
S278
P
D
F
S
Q
K
V
S
E
S
M
Q
Y
P
F
Site 33
Y283
K
V
S
E
S
M
Q
Y
P
F
K
P
C
M
R
Site 34
T302
D
K
R
H
L
C
R
T
R
V
A
V
V
E
S
Site 35
Y319
G
G
R
L
R
L
V
Y
E
E
S
E
D
R
T
Site 36
S322
L
R
L
V
Y
E
E
S
E
D
R
T
D
D
F
Site 37
T357
R
F
K
R
S
D
I
T
K
K
Q
D
G
H
F
Site 38
T366
K
Q
D
G
H
F
D
T
P
P
H
L
F
A
K
Site 39
S380
K
V
K
E
V
D
Q
S
G
E
W
F
K
E
G
Site 40
S422
L
M
I
G
I
D
G
S
E
A
A
D
G
S
D
Site 41
Y433
D
G
S
D
W
F
C
Y
H
A
T
S
P
S
I
Site 42
T454
E
I
N
M
I
E
L
T
P
P
R
G
Y
T
K
Site 43
Y459
E
L
T
P
P
R
G
Y
T
K
L
P
F
K
W
Site 44
T460
L
T
P
P
R
G
Y
T
K
L
P
F
K
W
F
Site 45
Y469
L
P
F
K
W
F
D
Y
L
R
E
T
G
S
I
Site 46
S475
D
Y
L
R
E
T
G
S
I
A
A
P
V
K
L
Site 47
S541
D
Q
W
V
D
C
E
S
P
D
L
Y
P
V
G
Site 48
Y545
D
C
E
S
P
D
L
Y
P
V
G
W
C
Q
L
Site 49
Y555
G
W
C
Q
L
T
G
Y
Q
L
Q
P
P
A
S
Site 50
S562
Y
Q
L
Q
P
P
A
S
Q
S
S
R
E
N
Q
Site 51
S564
L
Q
P
P
A
S
Q
S
S
R
E
N
Q
S
A
Site 52
S570
Q
S
S
R
E
N
Q
S
A
S
S
K
Q
K
K
Site 53
S572
S
R
E
N
Q
S
A
S
S
K
Q
K
K
K
A
Site 54
S581
K
Q
K
K
K
A
K
S
Q
Q
Y
K
G
H
K
Site 55
Y605
E
L
L
D
G
E
D
Y
N
F
L
Q
G
A
S
Site 56
S612
Y
N
F
L
Q
G
A
S
D
Q
E
S
N
G
S
Site 57
S616
Q
G
A
S
D
Q
E
S
N
G
S
A
N
F
Y
Site 58
S619
S
D
Q
E
S
N
G
S
A
N
F
Y
I
K
Q
Site 59
Y623
S
N
G
S
A
N
F
Y
I
K
Q
E
P
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation