PhosphoNET

           
Protein Info 
   
Short Name:  PAX8
Full Name:  Paired box protein Pax-8
Alias:  Paired box gene 8; Paired box Pax-8
Type:  Nucleus protein
Mass (Da):  48218
Number AA:  450
UniProt ID:  Q06710
International Prot ID:  IPI00306285
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005654     Uniprot OncoNet
Molecular Function:  GO:0005515  GO:0004996  GO:0016563 PhosphoSite+ KinaseNET
Biological Process:  GO:0009653  GO:0030154  GO:0006350 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S48GVRPCDISRQLRVSH
Site 2S54ISRQLRVSHGCVSKI
Site 3Y65VSKILGRYYETGSIR
Site 4Y66SKILGRYYETGSIRP
Site 5S70GRYYETGSIRPGVIG
Site 6T85GSKPKVATPKVVEKI
Site 7Y95VVEKIGDYKRQNPTM
Site 8T121EGVCDNDTVPSVSSI
Site 9S124CDNDTVPSVSSINRI
Site 10T150PMDSCVATKSLSPGH
Site 11S152DSCVATKSLSPGHTL
Site 12T158KSLSPGHTLIPSSAV
Site 13S162PGHTLIPSSAVTPPE
Site 14S163GHTLIPSSAVTPPES
Site 15T166LIPSSAVTPPESPQS
Site 16S170SAVTPPESPQSDSLG
Site 17S173TPPESPQSDSLGSTY
Site 18S175PESPQSDSLGSTYSI
Site 19S178PQSDSLGSTYSINGL
Site 20T179QSDSLGSTYSINGLL
Site 21Y180SDSLGSTYSINGLLG
Site 22S193LGIAQPGSDKRKMDD
Site 23S201DKRKMDDSDQDSCRL
Site 24S205MDDSDQDSCRLSIDS
Site 25S209DQDSCRLSIDSQSSS
Site 26S212SCRLSIDSQSSSSGP
Site 27S214RLSIDSQSSSSGPRK
Site 28S215LSIDSQSSSSGPRKH
Site 29S216SIDSQSSSSGPRKHL
Site 30S217IDSQSSSSGPRKHLR
Site 31T225GPRKHLRTDAFSQHH
Site 32S229HLRTDAFSQHHLEPL
Site 33Y245CPFERQHYPEAYASP
Site 34Y249RQHYPEAYASPSHTK
Site 35S251HYPEAYASPSHTKGE
Site 36S253PEAYASPSHTKGEQG
Site 37T255AYASPSHTKGEQGLY
Site 38Y262TKGEQGLYPLPLLNS
Site 39S269YPLPLLNSTLDDGKA
Site 40T277TLDDGKATLTPSNTP
Site 41T279DDGKATLTPSNTPLG
Site 42S281GKATLTPSNTPLGRN
Site 43T283ATLTPSNTPLGRNLS
Site 44S290TPLGRNLSTHQTYPV
Site 45T294RNLSTHQTYPVVADP
Site 46Y295NLSTHQTYPVVADPH
Site 47S303PVVADPHSPFAIKQE
Site 48T311PFAIKQETPEVSSSS
Site 49S315KQETPEVSSSSSTPS
Site 50S316QETPEVSSSSSTPSS
Site 51S317ETPEVSSSSSTPSSL
Site 52S318TPEVSSSSSTPSSLS
Site 53S319PEVSSSSSTPSSLSS
Site 54T320EVSSSSSTPSSLSSS
Site 55S322SSSSSTPSSLSSSAF
Site 56S323SSSSTPSSLSSSAFL
Site 57S325SSTPSSLSSSAFLDL
Site 58S326STPSSLSSSAFLDLQ
Site 59S327TPSSLSSSAFLDLQQ
Site 60S350NAFPHAASVYGQFTG
Site 61T370GREMVGPTLPGYPPH
Site 62Y374VGPTLPGYPPHIPTS
Site 63S381YPPHIPTSGQGSYAS
Site 64S385IPTSGQGSYASSAIA
Site 65Y405SEYSGNAYGHTPYSS
Site 66T408SGNAYGHTPYSSYSE
Site 67Y410NAYGHTPYSSYSEAW
Site 68S411AYGHTPYSSYSEAWR
Site 69S422EAWRFPNSSLLSSPY
Site 70S423AWRFPNSSLLSSPYY
Site 71S426FPNSSLLSSPYYYSS
Site 72S427PNSSLLSSPYYYSST
Site 73Y429SSLLSSPYYYSSTSR
Site 74Y430SLLSSPYYYSSTSRP
Site 75Y431LLSSPYYYSSTSRPS
Site 76S432LSSPYYYSSTSRPSA
Site 77S433SSPYYYSSTSRPSAP
Site 78T434SPYYYSSTSRPSAPP
Site 79S435PYYYSSTSRPSAPPT
Site 80S438YSSTSRPSAPPTTAT
Site 81T442SRPSAPPTTATAFDH
Site 82T443RPSAPPTTATAFDHL
Site 83T445SAPPTTATAFDHL__
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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