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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
EGR3
Full Name:
Early growth response protein 3
Alias:
Zinc finger protein pilot
Type:
Mass (Da):
42613
Number AA:
387
UniProt ID:
Q06889
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S14
E
K
L
P
V
T
M
S
S
L
L
N
Q
L
P
Site 2
S15
K
L
P
V
T
M
S
S
L
L
N
Q
L
P
D
Site 3
Y25
N
Q
L
P
D
N
L
Y
P
E
E
I
P
S
A
Site 4
S40
L
N
L
F
S
G
S
S
D
S
V
V
H
Y
N
Site 5
S42
L
F
S
G
S
S
D
S
V
V
H
Y
N
Q
M
Site 6
Y46
S
S
D
S
V
V
H
Y
N
Q
M
A
T
E
N
Site 7
S69
E
K
P
N
P
E
L
S
Y
S
G
S
F
Q
P
Site 8
S71
P
N
P
E
L
S
Y
S
G
S
F
Q
P
A
P
Site 9
S73
P
E
L
S
Y
S
G
S
F
Q
P
A
P
G
N
Site 10
T82
Q
P
A
P
G
N
K
T
V
T
Y
L
G
K
F
Site 11
Y85
P
G
N
K
T
V
T
Y
L
G
K
F
A
F
D
Site 12
S93
L
G
K
F
A
F
D
S
P
S
N
W
C
Q
D
Site 13
S121
P
P
A
S
G
A
L
S
T
Q
T
S
T
A
S
Site 14
T124
S
G
A
L
S
T
Q
T
S
T
A
S
M
V
Q
Site 15
S125
G
A
L
S
T
Q
T
S
T
A
S
M
V
Q
P
Site 16
S128
S
T
Q
T
S
T
A
S
M
V
Q
P
P
Q
G
Site 17
Y141
Q
G
D
V
E
A
M
Y
P
A
L
P
P
Y
S
Site 18
Y147
M
Y
P
A
L
P
P
Y
S
N
C
G
D
L
Y
Site 19
S148
Y
P
A
L
P
P
Y
S
N
C
G
D
L
Y
S
Site 20
Y154
Y
S
N
C
G
D
L
Y
S
E
P
V
S
F
H
Site 21
S155
S
N
C
G
D
L
Y
S
E
P
V
S
F
H
D
Site 22
S159
D
L
Y
S
E
P
V
S
F
H
D
P
Q
G
N
Site 23
S172
G
N
P
G
L
A
Y
S
P
Q
D
Y
Q
S
A
Site 24
Y176
L
A
Y
S
P
Q
D
Y
Q
S
A
K
P
A
L
Site 25
S178
Y
S
P
Q
D
Y
Q
S
A
K
P
A
L
D
S
Site 26
Y194
L
F
P
M
I
P
D
Y
N
L
Y
H
H
P
N
Site 27
Y197
M
I
P
D
Y
N
L
Y
H
H
P
N
D
M
G
Site 28
T226
R
V
N
P
P
P
I
T
P
L
E
T
I
K
A
Site 29
S245
Q
I
H
P
G
F
G
S
L
P
Q
P
P
L
T
Site 30
T252
S
L
P
Q
P
P
L
T
L
K
P
I
R
P
R
Site 31
Y261
K
P
I
R
P
R
K
Y
P
N
R
P
S
K
T
Site 32
S266
R
K
Y
P
N
R
P
S
K
T
P
L
H
E
R
Site 33
T268
Y
P
N
R
P
S
K
T
P
L
H
E
R
P
H
Site 34
S287
E
G
C
D
R
R
F
S
R
S
D
E
L
T
R
Site 35
S289
C
D
R
R
F
S
R
S
D
E
L
T
R
H
L
Site 36
T293
F
S
R
S
D
E
L
T
R
H
L
R
I
H
T
Site 37
T300
T
R
H
L
R
I
H
T
G
H
K
P
F
Q
C
Site 38
S313
Q
C
R
I
C
M
R
S
F
S
R
S
D
H
L
Site 39
S315
R
I
C
M
R
S
F
S
R
S
D
H
L
T
T
Site 40
S317
C
M
R
S
F
S
R
S
D
H
L
T
T
H
I
Site 41
T321
F
S
R
S
D
H
L
T
T
H
I
R
T
H
T
Site 42
T322
S
R
S
D
H
L
T
T
H
I
R
T
H
T
G
Site 43
T326
H
L
T
T
H
I
R
T
H
T
G
E
K
P
F
Site 44
T328
T
T
H
I
R
T
H
T
G
E
K
P
F
A
C
Site 45
S345
C
G
R
K
F
A
R
S
D
E
R
K
R
H
A
Site 46
S370
A
E
K
G
G
A
P
S
A
S
S
A
P
P
V
Site 47
S372
K
G
G
A
P
S
A
S
S
A
P
P
V
S
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation