PhosphoNET

           
Protein Info 
   
Short Name:  SOX4
Full Name:  Transcription factor SOX-4
Alias:  SRY (sex determining region Y)-box 4
Type:  Transcription factor
Mass (Da):  47263
Number AA:  474
UniProt ID:  Q06945
International Prot ID:  IPI00001617
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005737  GO:0005634   Uniprot OncoNet
Molecular Function:  GO:0005515  GO:0003700   PhosphoSite+ KinaseNET
Biological Process:  GO:0030217  GO:0060070  GO:0007507 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S19EALLAGESSDSGAGL
Site 2S20ALLAGESSDSGAGLE
Site 3S22LAGESSDSGAGLELG
Site 4T35LGIASSPTPGSTAST
Site 5S38ASSPTPGSTASTGGK
Site 6S41PTPGSTASTGGKADD
Site 7S50GGKADDPSWCKTPSG
Site 8T54DDPSWCKTPSGHIKR
Site 9S81RRKIMEQSPDMHNAE
Site 10S103RWKLLKDSDKIPFIR
Site 11Y123RLKHMADYPDYKYRP
Site 12Y126HMADYPDYKYRPRKK
Site 13Y128ADYPDYKYRPRKKVK
Site 14S136RPRKKVKSGNANSSS
Site 15S141VKSGNANSSSSAAAS
Site 16S142KSGNANSSSSAAASS
Site 17S143SGNANSSSSAAASSK
Site 18S144GNANSSSSAAASSKP
Site 19S148SSSSAAASSKPGEKG
Site 20S149SSSAAASSKPGEKGD
Site 21S161KGDKVGGSGGGGHGG
Site 22S174GGGGGGGSSNAGGGG
Site 23S175GGGGGGSSNAGGGGG
Site 24S185GGGGGGASGGGANSK
Site 25S191ASGGGANSKPAQKKS
Site 26S198SKPAQKKSCGSKVAG
Site 27S201AQKKSCGSKVAGGAG
Site 28S212GGAGGGVSKPHAKLI
Site 29S258GAAADHHSLYKARTP
Site 30Y260AADHHSLYKARTPSA
Site 31T264HSLYKARTPSASASA
Site 32S266LYKARTPSASASASS
Site 33S268KARTPSASASASSAA
Site 34S270RTPSASASASSAASA
Site 35S272PSASASASSAASASA
Site 36S276ASASSAASASAALAA
Site 37Y297EKKVKRVYLFGGLGT
Site 38S319VGAGADPSDPLGLYE
Site 39Y325PSDPLGLYEEEGAGC
Site 40S333EEEGAGCSPDAPSLS
Site 41S338GCSPDAPSLSGRSSA
Site 42S340SPDAPSLSGRSSAAS
Site 43S343APSLSGRSSAASSPA
Site 44S344PSLSGRSSAASSPAA
Site 45S347SGRSSAASSPAAGRS
Site 46S348GRSSAASSPAAGRSP
Site 47S354SSPAAGRSPADHRGY
Site 48Y361SPADHRGYASLRAAS
Site 49S363ADHRGYASLRAASPA
Site 50S368YASLRAASPAPSSAP
Site 51S372RAASPAPSSAPSHAS
Site 52S373AASPAPSSAPSHASS
Site 53S376PAPSSAPSHASSSAS
Site 54S379SSAPSHASSSASSHS
Site 55S380SAPSHASSSASSHSS
Site 56S381APSHASSSASSHSSS
Site 57S383SHASSSASSHSSSSS
Site 58S384HASSSASSHSSSSSS
Site 59S386SSSASSHSSSSSSSG
Site 60S387SSASSHSSSSSSSGS
Site 61S388SASSHSSSSSSSGSS
Site 62S389ASSHSSSSSSSGSSS
Site 63S390SSHSSSSSSSGSSSS
Site 64S391SHSSSSSSSGSSSSD
Site 65S392HSSSSSSSGSSSSDD
Site 66S394SSSSSSGSSSSDDEF
Site 67S395SSSSSGSSSSDDEFE
Site 68S396SSSSGSSSSDDEFED
Site 69S397SSSGSSSSDDEFEDD
Site 70S411DLLDLNPSSNFESMS
Site 71S412LLDLNPSSNFESMSL
Site 72S416NPSSNFESMSLGSFS
Site 73S418SSNFESMSLGSFSSS
Site 74S423SMSLGSFSSSSALDR
Site 75S424MSLGSFSSSSALDRD
Site 76S425SLGSFSSSSALDRDL
Site 77S426LGSFSSSSALDRDLD
Site 78S440DFNFEPGSGSHFEFP
Site 79S442NFEPGSGSHFEFPDY
Site 80Y449SHFEFPDYCTPEVSE
Site 81T451FEFPDYCTPEVSEMI
Site 82S459PEVSEMISGDWLESS
Site 83S466SGDWLESSISNLVFT
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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