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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CKAP4
Full Name:
Cytoskeleton-associated protein 4
Alias:
63 kDa membrane protein; CLIMP-63; ERGIC-63; P63
Type:
Endoplasmic reticulum
Mass (Da):
66022
Number AA:
602
UniProt ID:
Q07065
International Prot ID:
IPI00141318
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
GO:0005624
GO:0005626
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S3
_
_
_
_
_
M
P
S
A
K
Q
R
G
S
K
Site 2
S9
P
S
A
K
Q
R
G
S
K
G
G
H
G
A
A
Site 3
S17
K
G
G
H
G
A
A
S
P
S
E
K
G
A
H
Site 4
S19
G
H
G
A
A
S
P
S
E
K
G
A
H
P
S
Site 5
S79
G
G
G
G
G
G
K
S
S
S
S
S
S
A
S
Site 6
S80
G
G
G
G
G
K
S
S
S
S
S
S
A
S
A
Site 7
S81
G
G
G
G
K
S
S
S
S
S
S
A
S
A
A
Site 8
S82
G
G
G
K
S
S
S
S
S
S
A
S
A
A
A
Site 9
S83
G
G
K
S
S
S
S
S
S
A
S
A
A
A
A
Site 10
S84
G
K
S
S
S
S
S
S
A
S
A
A
A
A
A
Site 11
S97
A
A
A
A
A
S
S
S
A
S
C
S
R
R
L
Site 12
S99
A
A
A
S
S
S
A
S
C
S
R
R
L
G
R
Site 13
S101
A
S
S
S
A
S
C
S
R
R
L
G
R
A
L
Site 14
S140
E
V
Q
Q
V
R
R
S
H
Q
D
F
S
R
Q
Site 15
S145
R
R
S
H
Q
D
F
S
R
Q
R
E
E
L
G
Site 16
S164
G
V
E
Q
K
V
Q
S
L
Q
A
T
F
G
T
Site 17
T168
K
V
Q
S
L
Q
A
T
F
G
T
F
E
S
I
Site 18
S174
A
T
F
G
T
F
E
S
I
L
R
S
S
Q
H
Site 19
S178
T
F
E
S
I
L
R
S
S
Q
H
K
Q
D
L
Site 20
S179
F
E
S
I
L
R
S
S
Q
H
K
Q
D
L
T
Site 21
T186
S
Q
H
K
Q
D
L
T
E
K
A
V
K
Q
G
Site 22
S198
K
Q
G
E
S
E
V
S
R
I
S
E
V
L
Q
Site 23
S201
E
S
E
V
S
R
I
S
E
V
L
Q
K
L
Q
Site 24
S216
N
E
I
L
K
D
L
S
D
G
I
H
V
V
K
Site 25
T231
D
A
R
E
R
D
F
T
S
L
E
N
T
V
E
Site 26
S232
A
R
E
R
D
F
T
S
L
E
N
T
V
E
E
Site 27
T236
D
F
T
S
L
E
N
T
V
E
E
R
L
T
E
Site 28
T242
N
T
V
E
E
R
L
T
E
L
T
K
S
I
N
Site 29
T245
E
E
R
L
T
E
L
T
K
S
I
N
D
N
I
Site 30
S247
R
L
T
E
L
T
K
S
I
N
D
N
I
A
I
Site 31
S275
D
M
K
A
K
V
A
S
L
E
E
S
E
G
N
Site 32
S279
K
V
A
S
L
E
E
S
E
G
N
K
Q
D
L
Site 33
S299
A
V
K
E
I
Q
T
S
A
K
S
R
E
W
D
Site 34
S312
W
D
M
E
A
L
R
S
T
L
Q
T
M
E
S
Site 35
T313
D
M
E
A
L
R
S
T
L
Q
T
M
E
S
D
Site 36
T316
A
L
R
S
T
L
Q
T
M
E
S
D
I
Y
T
Site 37
S319
S
T
L
Q
T
M
E
S
D
I
Y
T
E
V
R
Site 38
Y322
Q
T
M
E
S
D
I
Y
T
E
V
R
E
L
V
Site 39
T323
T
M
E
S
D
I
Y
T
E
V
R
E
L
V
S
Site 40
S330
T
E
V
R
E
L
V
S
L
K
Q
E
Q
Q
A
Site 41
T344
A
F
K
E
A
A
D
T
E
R
L
A
L
Q
A
Site 42
S359
L
T
E
K
L
L
R
S
E
E
S
V
S
R
L
Site 43
S362
K
L
L
R
S
E
E
S
V
S
R
L
P
E
E
Site 44
S364
L
R
S
E
E
S
V
S
R
L
P
E
E
I
R
Site 45
S382
E
E
L
R
Q
L
K
S
D
S
H
G
P
K
E
Site 46
S384
L
R
Q
L
K
S
D
S
H
G
P
K
E
D
G
Site 47
S396
E
D
G
G
F
R
H
S
E
A
F
E
A
L
Q
Site 48
S406
F
E
A
L
Q
Q
K
S
Q
G
L
D
S
R
L
Site 49
S411
Q
K
S
Q
G
L
D
S
R
L
Q
H
V
E
D
Site 50
S422
H
V
E
D
G
V
L
S
M
Q
V
A
S
A
R
Site 51
S427
V
L
S
M
Q
V
A
S
A
R
Q
T
E
S
L
Site 52
T431
Q
V
A
S
A
R
Q
T
E
S
L
E
S
L
L
Site 53
S433
A
S
A
R
Q
T
E
S
L
E
S
L
L
S
K
Site 54
S436
R
Q
T
E
S
L
E
S
L
L
S
K
S
Q
E
Site 55
S439
E
S
L
E
S
L
L
S
K
S
Q
E
H
E
Q
Site 56
S441
L
E
S
L
L
S
K
S
Q
E
H
E
Q
R
L
Site 57
S460
G
R
L
E
G
L
G
S
S
E
A
D
Q
D
G
Site 58
S461
R
L
E
G
L
G
S
S
E
A
D
Q
D
G
L
Site 59
S470
A
D
Q
D
G
L
A
S
T
V
R
S
L
G
E
Site 60
T471
D
Q
D
G
L
A
S
T
V
R
S
L
G
E
T
Site 61
T478
T
V
R
S
L
G
E
T
Q
L
V
L
Y
G
D
Site 62
Y483
G
E
T
Q
L
V
L
Y
G
D
V
E
E
L
K
Site 63
S492
D
V
E
E
L
K
R
S
V
G
E
L
P
S
T
Site 64
S498
R
S
V
G
E
L
P
S
T
V
E
S
L
Q
K
Site 65
T499
S
V
G
E
L
P
S
T
V
E
S
L
Q
K
V
Site 66
S502
E
L
P
S
T
V
E
S
L
Q
K
V
Q
E
Q
Site 67
T512
K
V
Q
E
Q
V
H
T
L
L
S
Q
D
Q
A
Site 68
S515
E
Q
V
H
T
L
L
S
Q
D
Q
A
Q
A
A
Site 69
S534
Q
D
F
L
D
R
L
S
S
L
D
N
L
K
A
Site 70
S535
D
F
L
D
R
L
S
S
L
D
N
L
K
A
S
Site 71
S542
S
L
D
N
L
K
A
S
V
S
Q
V
E
A
D
Site 72
S544
D
N
L
K
A
S
V
S
Q
V
E
A
D
L
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation