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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TCHH
Full Name:
Trichohyalin
Alias:
Type:
Mass (Da):
253925
Number AA:
1943
UniProt ID:
Q07283
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005856
Uniprot
OncoNet
Molecular Function:
GO:0005509
PhosphoSite+
KinaseNET
Biological Process:
GO:0031424
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y18
I
T
E
I
F
N
Q
Y
V
S
H
D
C
D
G
Site 2
T53
R
R
P
H
D
P
K
T
V
D
L
I
L
E
L
Site 3
S65
L
E
L
L
D
L
D
S
N
G
R
V
D
F
N
Site 4
S195
A
E
E
E
Q
L
Q
S
C
K
G
H
E
T
E
Site 5
T251
K
E
W
R
K
R
E
T
V
L
R
K
E
E
E
Site 6
S534
R
L
Q
Q
R
L
R
S
E
Q
Q
L
R
R
E
Site 7
S636
R
R
Q
Q
L
L
K
S
E
E
Q
E
E
R
R
Site 8
S699
Q
A
R
E
R
I
K
S
R
I
P
K
W
Q
W
Site 9
S717
S
E
A
D
A
R
Q
S
K
V
Y
S
R
P
R
Site 10
Y720
D
A
R
Q
S
K
V
Y
S
R
P
R
K
Q
E
Site 11
S721
A
R
Q
S
K
V
Y
S
R
P
R
K
Q
E
G
Site 12
S744
E
K
R
R
R
R
E
S
E
L
Q
W
Q
E
E
Site 13
S777
Q
W
Q
A
E
E
K
S
E
R
G
R
Q
R
L
Site 14
S785
E
R
G
R
Q
R
L
S
A
R
P
P
L
R
E
Site 15
S865
E
D
Q
E
R
R
R
S
Q
E
Q
R
R
D
Q
Site 16
T888
E
R
K
R
R
R
H
T
L
Y
A
K
P
A
L
Site 17
Y890
K
R
R
R
H
T
L
Y
A
K
P
A
L
Q
E
Site 18
Y930
R
Q
E
Q
E
R
Q
Y
R
E
E
E
Q
L
Q
Site 19
Y960
R
Q
E
R
E
R
Q
Y
R
K
D
K
K
L
Q
Site 20
Y990
R
Q
E
R
E
K
K
Y
R
E
E
E
E
L
Q
Site 21
Y1020
R
Q
E
W
E
R
Q
Y
R
K
K
D
E
L
Q
Site 22
Y1050
L
Q
E
R
E
R
Q
Y
R
E
E
E
E
L
Q
Site 23
T1070
L
L
G
E
E
R
E
T
R
R
R
Q
E
L
E
Site 24
Y1080
R
Q
E
L
E
R
Q
Y
R
K
E
E
E
L
Q
Site 25
Y1140
R
Q
E
L
E
R
Q
Y
R
E
E
E
E
V
Q
Site 26
Y1170
R
Q
E
L
E
R
Q
Y
R
E
E
E
E
L
Q
Site 27
Y1199
R
Q
E
R
E
R
Q
Y
R
E
E
E
E
L
Q
Site 28
Y1241
A
V
R
D
N
K
V
Y
C
K
G
R
E
N
E
Site 29
S1256
Q
F
R
Q
L
E
D
S
Q
L
R
D
R
Q
S
Site 30
S1263
S
Q
L
R
D
R
Q
S
Q
Q
D
L
Q
H
L
Site 31
S1314
A
K
R
R
D
R
K
S
Q
E
E
K
Q
L
L
Site 32
T1334
E
K
R
R
R
Q
E
T
D
R
K
F
R
E
E
Site 33
S1424
R
E
E
E
Q
Q
L
S
R
Q
E
R
D
R
K
Site 34
S1510
F
R
E
Q
E
L
R
S
Q
E
P
E
R
K
F
Site 35
S1573
E
R
E
E
Q
Q
L
S
R
Q
E
R
D
R
K
Site 36
T1735
E
E
Q
L
R
Q
E
T
E
Q
E
Q
L
R
R
Site 37
Y1746
Q
L
R
R
Q
E
R
Y
R
K
I
L
E
E
E
Site 38
S1790
R
E
E
Q
Q
L
R
S
Q
E
S
D
R
K
F
Site 39
S1793
Q
Q
L
R
S
Q
E
S
D
R
K
F
R
E
E
Site 40
Y1821
P
Q
Q
R
D
G
K
Y
R
W
E
E
E
Q
L
Site 41
Y1845
R
Q
E
R
D
R
Q
Y
R
A
E
E
Q
F
A
Site 42
T1853
R
A
E
E
Q
F
A
T
Q
E
K
S
R
R
E
Site 43
S1857
Q
F
A
T
Q
E
K
S
R
R
E
E
Q
E
L
Site 44
S1903
R
Q
V
G
E
I
K
S
Q
E
G
K
G
H
G
Site 45
T1917
G
R
L
L
E
P
G
T
H
Q
F
A
S
V
P
Site 46
S1922
P
G
T
H
Q
F
A
S
V
P
V
R
S
S
P
Site 47
S1928
A
S
V
P
V
R
S
S
P
L
Y
E
Y
I
Q
Site 48
Y1931
P
V
R
S
S
P
L
Y
E
Y
I
Q
E
Q
R
Site 49
Y1933
R
S
S
P
L
Y
E
Y
I
Q
E
Q
R
S
Q
Site 50
S1939
E
Y
I
Q
E
Q
R
S
Q
Y
R
P
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation