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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SPAG1
Full Name:
Sperm-associated antigen 1
Alias:
FLJ32920; HSD-3.8; SP75; sperm associated antigen 1; TPIS
Type:
Microtubule binding protein
Mass (Da):
103600
Number AA:
926
UniProt ID:
Q07617
International Prot ID:
IPI00784144
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
Uniprot
OncoNet
Molecular Function:
GO:0005525
GO:0016787
PhosphoSite+
KinaseNET
Biological Process:
GO:0007338
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y6
_
_
M
T
T
K
D
Y
P
S
L
W
G
F
G
Site 2
T14
P
S
L
W
G
F
G
T
T
K
T
F
K
I
P
Site 3
T17
W
G
F
G
T
T
K
T
F
K
I
P
I
E
H
Site 4
Y29
I
E
H
L
D
F
K
Y
I
E
K
C
S
D
V
Site 5
S48
K
I
L
C
V
L
R
S
G
E
E
G
Y
Y
P
Site 6
Y54
R
S
G
E
E
G
Y
Y
P
E
L
T
E
F
C
Site 7
T58
E
G
Y
Y
P
E
L
T
E
F
C
E
K
H
L
Site 8
S86
K
P
A
A
T
A
A
S
F
T
A
E
E
W
E
Site 9
S101
K
I
D
G
D
I
K
S
W
V
S
E
I
K
K
Site 10
S134
N
L
P
P
V
R
G
S
N
S
C
L
H
V
G
Site 11
S136
P
P
V
R
G
S
N
S
C
L
H
V
G
K
E
Site 12
Y145
L
H
V
G
K
E
K
Y
S
K
R
P
T
K
K
Site 13
S146
H
V
G
K
E
K
Y
S
K
R
P
T
K
K
K
Site 14
T150
E
K
Y
S
K
R
P
T
K
K
K
T
P
R
D
Site 15
T154
K
R
P
T
K
K
K
T
P
R
D
Y
A
E
W
Site 16
Y158
K
K
K
T
P
R
D
Y
A
E
W
D
K
F
D
Site 17
Y177
C
L
K
I
D
E
D
Y
K
E
K
T
V
I
D
Site 18
T181
D
E
D
Y
K
E
K
T
V
I
D
K
S
H
L
Site 19
S186
E
K
T
V
I
D
K
S
H
L
S
K
I
E
T
Site 20
S189
V
I
D
K
S
H
L
S
K
I
E
T
R
I
D
Site 21
T193
S
H
L
S
K
I
E
T
R
I
D
T
A
G
L
Site 22
T197
K
I
E
T
R
I
D
T
A
G
L
T
E
K
E
Site 23
S222
K
G
N
E
A
F
N
S
G
D
Y
E
E
A
V
Site 24
Y225
E
A
F
N
S
G
D
Y
E
E
A
V
M
Y
Y
Site 25
Y231
D
Y
E
E
A
V
M
Y
Y
T
R
S
I
S
A
Site 26
Y232
Y
E
E
A
V
M
Y
Y
T
R
S
I
S
A
L
Site 27
T241
R
S
I
S
A
L
P
T
V
V
A
Y
N
N
R
Site 28
T284
K
A
L
L
R
R
A
T
T
Y
K
H
Q
N
K
Site 29
T285
A
L
L
R
R
A
T
T
Y
K
H
Q
N
K
L
Site 30
Y286
L
L
R
R
A
T
T
Y
K
H
Q
N
K
L
R
Site 31
T296
Q
N
K
L
R
E
A
T
E
D
L
S
K
V
L
Site 32
S300
R
E
A
T
E
D
L
S
K
V
L
D
V
E
P
Site 33
T315
D
N
D
L
A
K
K
T
L
S
E
V
E
R
D
Site 34
S317
D
L
A
K
K
T
L
S
E
V
E
R
D
L
K
Site 35
S326
V
E
R
D
L
K
N
S
E
A
A
S
E
T
Q
Site 36
S330
L
K
N
S
E
A
A
S
E
T
Q
T
K
G
K
Site 37
T334
E
A
A
S
E
T
Q
T
K
G
K
R
M
V
I
Site 38
S347
V
I
Q
E
I
E
N
S
E
D
E
E
G
K
S
Site 39
S354
S
E
D
E
E
G
K
S
G
R
K
H
E
D
G
Site 40
T409
G
A
P
Q
R
G
Q
T
P
E
A
G
A
D
K
Site 41
S418
E
A
G
A
D
K
R
S
P
R
R
A
S
A
A
Site 42
S423
K
R
S
P
R
R
A
S
A
A
A
A
A
G
G
Site 43
T433
A
A
A
G
G
G
A
T
G
H
P
G
G
G
Q
Site 44
S450
E
N
P
A
G
L
K
S
Q
G
N
E
L
F
R
Site 45
S458
Q
G
N
E
L
F
R
S
G
Q
F
A
E
A
A
Site 46
S487
S
E
I
A
D
D
L
S
I
L
Y
S
N
R
A
Site 47
Y490
A
D
D
L
S
I
L
Y
S
N
R
A
A
C
Y
Site 48
Y497
Y
S
N
R
A
A
C
Y
L
K
E
G
N
C
S
Site 49
S520
A
L
E
L
H
P
F
S
M
K
P
L
L
R
R
Site 50
Y531
L
L
R
R
A
M
A
Y
E
T
L
E
Q
Y
G
Site 51
Y537
A
Y
E
T
L
E
Q
Y
G
K
A
Y
V
D
Y
Site 52
Y541
L
E
Q
Y
G
K
A
Y
V
D
Y
K
T
V
L
Site 53
Y544
Y
G
K
A
Y
V
D
Y
K
T
V
L
Q
I
D
Site 54
T546
K
A
Y
V
D
Y
K
T
V
L
Q
I
D
C
G
Site 55
S560
G
L
Q
L
A
N
D
S
V
N
R
L
S
R
I
Site 56
S565
N
D
S
V
N
R
L
S
R
I
L
M
E
L
D
Site 57
S581
P
N
W
R
E
K
L
S
P
I
P
A
V
P
A
Site 58
S603
H
P
A
K
E
M
I
S
K
Q
A
G
D
S
S
Site 59
S609
I
S
K
Q
A
G
D
S
S
S
H
R
Q
Q
G
Site 60
S610
S
K
Q
A
G
D
S
S
S
H
R
Q
Q
G
I
Site 61
S611
K
Q
A
G
D
S
S
S
H
R
Q
Q
G
I
T
Site 62
T618
S
H
R
Q
Q
G
I
T
D
E
K
T
F
K
A
Site 63
T622
Q
G
I
T
D
E
K
T
F
K
A
L
K
E
E
Site 64
Y639
Q
C
V
N
D
K
N
Y
K
D
A
L
S
K
Y
Site 65
S644
K
N
Y
K
D
A
L
S
K
Y
S
E
C
L
K
Site 66
Y646
Y
K
D
A
L
S
K
Y
S
E
C
L
K
I
N
Site 67
S647
K
D
A
L
S
K
Y
S
E
C
L
K
I
N
N
Site 68
Y660
N
N
K
E
C
A
I
Y
T
N
R
A
L
C
Y
Site 69
T661
N
K
E
C
A
I
Y
T
N
R
A
L
C
Y
L
Site 70
Y695
D
G
N
V
K
A
F
Y
R
R
A
L
A
H
K
Site 71
S710
G
L
K
N
Y
Q
K
S
L
I
D
L
N
K
V
Site 72
T744
L
L
N
L
K
D
K
T
A
P
F
N
K
E
K
Site 73
S782
V
S
M
G
C
L
A
S
E
K
G
G
K
S
S
Site 74
S788
A
S
E
K
G
G
K
S
S
R
S
P
E
D
P
Site 75
S789
S
E
K
G
G
K
S
S
R
S
P
E
D
P
E
Site 76
S791
K
G
G
K
S
S
R
S
P
E
D
P
E
K
L
Site 77
S817
G
Q
I
I
N
A
L
S
T
R
K
D
K
E
A
Site 78
S842
K
D
L
P
M
F
L
S
N
K
L
E
G
D
T
Site 79
T849
S
N
K
L
E
G
D
T
F
L
L
L
I
Q
S
Site 80
S867
N
L
I
E
K
D
P
S
L
V
Y
Q
H
L
L
Site 81
Y870
E
K
D
P
S
L
V
Y
Q
H
L
L
Y
L
S
Site 82
Y875
L
V
Y
Q
H
L
L
Y
L
S
K
A
E
R
F
Site 83
S877
Y
Q
H
L
L
Y
L
S
K
A
E
R
F
K
M
Site 84
T887
E
R
F
K
M
M
L
T
L
I
S
K
G
Q
K
Site 85
S905
E
Q
L
F
E
D
L
S
D
T
P
N
N
H
F
Site 86
T907
L
F
E
D
L
S
D
T
P
N
N
H
F
T
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation