PhosphoNET

           
Protein Info 
   
Short Name:  DLX2
Full Name:  Homeobox protein DLX-2
Alias:  Distal-less homeobox 2; TES1; TES-1
Type:  Nucleus protein
Mass (Da):  34243
Number AA:  328
UniProt ID:  Q07687
International Prot ID:  IPI00018974
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005634     Uniprot OncoNet
Molecular Function:  GO:0043565  GO:0003700   PhosphoSite+ KinaseNET
Biological Process:      Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S31HQHQQPPSGGGAGPG
Site 2S41GAGPGGNSSSSSSLH
Site 3S42AGPGGNSSSSSSLHK
Site 4S43GPGGNSSSSSSLHKP
Site 5S44PGGNSSSSSSLHKPQ
Site 6S45GGNSSSSSSLHKPQE
Site 7S46GNSSSSSSLHKPQES
Site 8S53SLHKPQESPTLPVST
Site 9T55HKPQESPTLPVSTAT
Site 10S59ESPTLPVSTATDSSY
Site 11T60SPTLPVSTATDSSYY
Site 12S64PVSTATDSSYYTNQQ
Site 13Y66STATDSSYYTNQQHP
Site 14T68ATDSSYYTNQQHPAG
Site 15S82GGGGGGGSPYAHMGS
Site 16Y84GGGGGSPYAHMGSYQ
Site 17S89SPYAHMGSYQYQASG
Site 18Y90PYAHMGSYQYQASGL
Site 19Y92AHMGSYQYQASGLNN
Site 20Y102SGLNNVPYSAKSSYD
Site 21S103GLNNVPYSAKSSYDL
Site 22S106NVPYSAKSSYDLGYT
Site 23S107VPYSAKSSYDLGYTA
Site 24Y112KSSYDLGYTAAYTSY
Site 25T113SSYDLGYTAAYTSYA
Site 26Y116DLGYTAAYTSYAPYG
Site 27S118GYTAAYTSYAPYGTS
Site 28Y122AYTSYAPYGTSSSPA
Site 29S127APYGTSSSPANNEPE
Site 30T157KKVRKPRTIYSSFQL
Site 31Y159VRKPRTIYSSFQLAA
Site 32S160RKPRTIYSSFQLAAL
Site 33S161KPRTIYSSFQLAALQ
Site 34T174LQRRFQKTQYLALPE
Site 35Y176RRFQKTQYLALPERA
Site 36S188ERAELAASLGLTQTQ
Site 37S213KFKKMWKSGEIPSEQ
Site 38S225SEQHPGASASPPCAS
Site 39S227QHPGASASPPCASPP
Site 40S232SASPPCASPPVSAPA
Site 41S236PCASPPVSAPASWDF
Site 42S240PPVSAPASWDFGVPQ
Site 43S257AGGGGPGSGGSGAGS
Site 44S260GGPGSGGSGAGSSGS
Site 45S264SGGSGAGSSGSSPSS
Site 46S265GGSGAGSSGSSPSSA
Site 47S267SGAGSSGSSPSSAAS
Site 48S268GAGSSGSSPSSAASA
Site 49S270GSSGSSPSSAASAFL
Site 50S271SSGSSPSSAASAFLG
Site 51S274SSPSSAASAFLGNYP
Site 52Y280ASAFLGNYPWYHQTS
Site 53Y283FLGNYPWYHQTSGSA
Site 54S289WYHQTSGSASHLQAT
Site 55S291HQTSGSASHLQATAP
Site 56T303TAPLLHPTQTPQPHH
Site 57T305PLLHPTQTPQPHHHH
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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