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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
DLX2
Full Name:
Homeobox protein DLX-2
Alias:
Distal-less homeobox 2; TES1; TES-1
Type:
Nucleus protein
Mass (Da):
34243
Number AA:
328
UniProt ID:
Q07687
International Prot ID:
IPI00018974
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0043565
GO:0003700
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S31
H
Q
H
Q
Q
P
P
S
G
G
G
A
G
P
G
Site 2
S41
G
A
G
P
G
G
N
S
S
S
S
S
S
L
H
Site 3
S42
A
G
P
G
G
N
S
S
S
S
S
S
L
H
K
Site 4
S43
G
P
G
G
N
S
S
S
S
S
S
L
H
K
P
Site 5
S44
P
G
G
N
S
S
S
S
S
S
L
H
K
P
Q
Site 6
S45
G
G
N
S
S
S
S
S
S
L
H
K
P
Q
E
Site 7
S46
G
N
S
S
S
S
S
S
L
H
K
P
Q
E
S
Site 8
S53
S
L
H
K
P
Q
E
S
P
T
L
P
V
S
T
Site 9
T55
H
K
P
Q
E
S
P
T
L
P
V
S
T
A
T
Site 10
S59
E
S
P
T
L
P
V
S
T
A
T
D
S
S
Y
Site 11
T60
S
P
T
L
P
V
S
T
A
T
D
S
S
Y
Y
Site 12
S64
P
V
S
T
A
T
D
S
S
Y
Y
T
N
Q
Q
Site 13
Y66
S
T
A
T
D
S
S
Y
Y
T
N
Q
Q
H
P
Site 14
T68
A
T
D
S
S
Y
Y
T
N
Q
Q
H
P
A
G
Site 15
S82
G
G
G
G
G
G
G
S
P
Y
A
H
M
G
S
Site 16
Y84
G
G
G
G
G
S
P
Y
A
H
M
G
S
Y
Q
Site 17
S89
S
P
Y
A
H
M
G
S
Y
Q
Y
Q
A
S
G
Site 18
Y90
P
Y
A
H
M
G
S
Y
Q
Y
Q
A
S
G
L
Site 19
Y92
A
H
M
G
S
Y
Q
Y
Q
A
S
G
L
N
N
Site 20
Y102
S
G
L
N
N
V
P
Y
S
A
K
S
S
Y
D
Site 21
S103
G
L
N
N
V
P
Y
S
A
K
S
S
Y
D
L
Site 22
S106
N
V
P
Y
S
A
K
S
S
Y
D
L
G
Y
T
Site 23
S107
V
P
Y
S
A
K
S
S
Y
D
L
G
Y
T
A
Site 24
Y112
K
S
S
Y
D
L
G
Y
T
A
A
Y
T
S
Y
Site 25
T113
S
S
Y
D
L
G
Y
T
A
A
Y
T
S
Y
A
Site 26
Y116
D
L
G
Y
T
A
A
Y
T
S
Y
A
P
Y
G
Site 27
S118
G
Y
T
A
A
Y
T
S
Y
A
P
Y
G
T
S
Site 28
Y122
A
Y
T
S
Y
A
P
Y
G
T
S
S
S
P
A
Site 29
S127
A
P
Y
G
T
S
S
S
P
A
N
N
E
P
E
Site 30
T157
K
K
V
R
K
P
R
T
I
Y
S
S
F
Q
L
Site 31
Y159
V
R
K
P
R
T
I
Y
S
S
F
Q
L
A
A
Site 32
S160
R
K
P
R
T
I
Y
S
S
F
Q
L
A
A
L
Site 33
S161
K
P
R
T
I
Y
S
S
F
Q
L
A
A
L
Q
Site 34
T174
L
Q
R
R
F
Q
K
T
Q
Y
L
A
L
P
E
Site 35
Y176
R
R
F
Q
K
T
Q
Y
L
A
L
P
E
R
A
Site 36
S188
E
R
A
E
L
A
A
S
L
G
L
T
Q
T
Q
Site 37
S213
K
F
K
K
M
W
K
S
G
E
I
P
S
E
Q
Site 38
S225
S
E
Q
H
P
G
A
S
A
S
P
P
C
A
S
Site 39
S227
Q
H
P
G
A
S
A
S
P
P
C
A
S
P
P
Site 40
S232
S
A
S
P
P
C
A
S
P
P
V
S
A
P
A
Site 41
S236
P
C
A
S
P
P
V
S
A
P
A
S
W
D
F
Site 42
S240
P
P
V
S
A
P
A
S
W
D
F
G
V
P
Q
Site 43
S257
A
G
G
G
G
P
G
S
G
G
S
G
A
G
S
Site 44
S260
G
G
P
G
S
G
G
S
G
A
G
S
S
G
S
Site 45
S264
S
G
G
S
G
A
G
S
S
G
S
S
P
S
S
Site 46
S265
G
G
S
G
A
G
S
S
G
S
S
P
S
S
A
Site 47
S267
S
G
A
G
S
S
G
S
S
P
S
S
A
A
S
Site 48
S268
G
A
G
S
S
G
S
S
P
S
S
A
A
S
A
Site 49
S270
G
S
S
G
S
S
P
S
S
A
A
S
A
F
L
Site 50
S271
S
S
G
S
S
P
S
S
A
A
S
A
F
L
G
Site 51
S274
S
S
P
S
S
A
A
S
A
F
L
G
N
Y
P
Site 52
Y280
A
S
A
F
L
G
N
Y
P
W
Y
H
Q
T
S
Site 53
Y283
F
L
G
N
Y
P
W
Y
H
Q
T
S
G
S
A
Site 54
S289
W
Y
H
Q
T
S
G
S
A
S
H
L
Q
A
T
Site 55
S291
H
Q
T
S
G
S
A
S
H
L
Q
A
T
A
P
Site 56
T303
T
A
P
L
L
H
P
T
Q
T
P
Q
P
H
H
Site 57
T305
P
L
L
H
P
T
Q
T
P
Q
P
H
H
H
H
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation