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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
KLC1
Full Name:
Kinesin light chain 1
Alias:
Kinesin 2; KLC; KLC 1
Type:
Kinesin complex, Axon, Microtubule, Cytoplasm, Ciliary rootlet, Cytosol, Cytoplasmic vesicle protein
Mass (Da):
65310
Number AA:
573
UniProt ID:
Q07866
International Prot ID:
IPI00337460
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005829
GO:0005871
GO:0005874
Uniprot
OncoNet
Molecular Function:
GO:0003777
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0007018
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y2
_
_
_
_
_
_
M
Y
D
N
M
S
T
M
V
Site 2
Y10
D
N
M
S
T
M
V
Y
I
K
E
D
K
L
E
Site 3
S44
A
L
K
N
E
H
N
S
I
L
Q
S
L
L
E
Site 4
S48
E
H
N
S
I
L
Q
S
L
L
E
T
L
K
C
Site 5
S62
C
L
K
K
D
D
E
S
N
L
V
E
E
K
S
Site 6
S69
S
N
L
V
E
E
K
S
N
M
I
R
K
S
L
Site 7
S75
K
S
N
M
I
R
K
S
L
E
M
L
E
L
G
Site 8
S101
N
H
L
N
A
V
E
S
E
K
Q
K
L
R
A
Site 9
T127
L
R
D
E
L
A
N
T
Q
Q
K
L
Q
K
S
Site 10
Y157
F
M
N
Q
L
K
K
Y
D
D
D
I
S
P
S
Site 11
S162
K
K
Y
D
D
D
I
S
P
S
E
D
K
D
T
Site 12
S164
Y
D
D
D
I
S
P
S
E
D
K
D
T
D
S
Site 13
T169
S
P
S
E
D
K
D
T
D
S
T
K
E
P
L
Site 14
S171
S
E
D
K
D
T
D
S
T
K
E
P
L
D
D
Site 15
T172
E
D
K
D
T
D
S
T
K
E
P
L
D
D
L
Site 16
Y207
A
A
A
Q
Q
G
G
Y
E
I
P
A
R
L
R
Site 17
Y223
L
H
N
L
V
I
Q
Y
A
S
Q
G
R
Y
E
Site 18
Y229
Q
Y
A
S
Q
G
R
Y
E
V
A
V
P
L
C
Site 19
Y271
V
Y
R
D
Q
N
K
Y
K
D
A
A
N
L
L
Site 20
T288
A
L
A
I
R
E
K
T
L
G
K
D
H
P
A
Site 21
Y307
L
N
N
L
A
V
L
Y
G
K
R
G
K
Y
K
Site 22
Y313
L
Y
G
K
R
G
K
Y
K
E
A
E
P
L
C
Site 23
Y355
L
C
Q
N
Q
G
K
Y
E
E
V
E
Y
Y
Y
Site 24
Y360
G
K
Y
E
E
V
E
Y
Y
Y
Q
R
A
L
E
Site 25
Y361
K
Y
E
E
V
E
Y
Y
Y
Q
R
A
L
E
I
Site 26
Y362
Y
E
E
V
E
Y
Y
Y
Q
R
A
L
E
I
Y
Site 27
Y369
Y
Q
R
A
L
E
I
Y
Q
T
K
L
G
P
D
Site 28
T371
R
A
L
E
I
Y
Q
T
K
L
G
P
D
D
P
Site 29
Y391
K
N
N
L
A
S
C
Y
L
K
Q
G
K
F
K
Site 30
Y404
F
K
Q
A
E
T
L
Y
K
E
I
L
T
R
A
Site 31
T444
K
G
K
Q
K
D
G
T
S
F
G
E
Y
G
G
Site 32
S445
G
K
Q
K
D
G
T
S
F
G
E
Y
G
G
W
Site 33
Y449
D
G
T
S
F
G
E
Y
G
G
W
Y
K
A
C
Site 34
Y453
F
G
E
Y
G
G
W
Y
K
A
C
K
V
D
S
Site 35
S460
Y
K
A
C
K
V
D
S
P
T
V
T
T
T
L
Site 36
T462
A
C
K
V
D
S
P
T
V
T
T
T
L
K
N
Site 37
T464
K
V
D
S
P
T
V
T
T
T
L
K
N
L
G
Site 38
T465
V
D
S
P
T
V
T
T
T
L
K
N
L
G
A
Site 39
T466
D
S
P
T
V
T
T
T
L
K
N
L
G
A
L
Site 40
Y474
L
K
N
L
G
A
L
Y
R
R
Q
G
K
F
E
Site 41
T485
G
K
F
E
A
A
E
T
L
E
E
A
A
M
R
Site 42
S521
E
N
M
E
K
R
R
S
R
E
S
L
N
V
D
Site 43
S524
E
K
R
R
S
R
E
S
L
N
V
D
V
V
K
Site 44
Y532
L
N
V
D
V
V
K
Y
E
S
G
P
D
G
G
Site 45
S543
P
D
G
G
E
E
V
S
M
S
V
E
W
N
G
Site 46
S545
G
G
E
E
V
S
M
S
V
E
W
N
G
G
V
Site 47
S553
V
E
W
N
G
G
V
S
G
R
A
S
F
C
G
Site 48
S557
G
G
M
K
R
A
S
S
L
N
V
L
N
V
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation