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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
FOXM1
Full Name:
Forkhead box protein M1
Alias:
FKH16; FKHL16; Forkhead box M1; Forkhead homolog 16; Forkhead-related protein FKHL16; FXM1; Hepatocyte nuclear factor 3 forkhead homolog 11; HFH11; HFH-11; HNF-3; HNF-3/fork-head homolog-11; INS-1; M-phase phosphoprotein 2; MPHOSPH2; MPM-2 reactive phosphoprotein 2; MPP2; TGT3; Transcription factor Trident; Trident; WIN; Winged helix factor from INS-1 cells; Winged-helix factor from INS-1 cells; Winged-helix transcription factor Trident
Type:
Transcription protein
Mass (Da):
84283
Number AA:
763
UniProt ID:
Q08050
International Prot ID:
IPI00032162
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003702
GO:0005515
GO:0043565
PhosphoSite+
KinaseNET
Biological Process:
GO:0007049
GO:0001558
GO:0042127
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S4
_
_
_
_
M
K
T
S
P
R
R
P
L
I
L
Site 2
S25
L
P
V
Q
N
A
P
S
E
T
S
E
E
E
P
Site 3
S35
S
E
E
E
P
K
R
S
P
A
Q
Q
E
S
N
Site 4
S41
R
S
P
A
Q
Q
E
S
N
Q
A
E
A
S
K
Site 5
S53
A
S
K
E
V
A
E
S
N
S
C
K
F
P
A
Site 6
T73
N
H
P
T
M
P
N
T
Q
V
V
A
I
P
N
Site 7
S98
L
T
A
K
G
K
E
S
G
S
S
G
P
N
K
Site 8
S100
A
K
G
K
E
S
G
S
S
G
P
N
K
F
I
Site 9
S101
K
G
K
E
S
G
S
S
G
P
N
K
F
I
L
Site 10
T116
I
S
C
G
G
A
P
T
Q
P
P
G
L
R
P
Site 11
T125
P
P
G
L
R
P
Q
T
Q
T
S
Y
D
A
K
Site 12
T127
G
L
R
P
Q
T
Q
T
S
Y
D
A
K
R
T
Site 13
Y129
R
P
Q
T
Q
T
S
Y
D
A
K
R
T
E
V
Site 14
T140
R
T
E
V
T
L
E
T
L
G
P
K
P
A
A
Site 15
T166
L
C
E
Q
K
R
E
T
C
A
D
G
E
A
A
Site 16
T176
D
G
E
A
A
G
C
T
I
N
N
S
L
S
N
Site 17
S191
I
Q
W
L
R
K
M
S
S
D
G
L
G
S
R
Site 18
S192
Q
W
L
R
K
M
S
S
D
G
L
G
S
R
S
Site 19
S197
M
S
S
D
G
L
G
S
R
S
I
K
Q
E
M
Site 20
S223
Q
V
K
V
E
E
P
S
R
P
S
A
S
W
Q
Site 21
S226
V
E
E
P
S
R
P
S
A
S
W
Q
N
S
V
Site 22
S228
E
P
S
R
P
S
A
S
W
Q
N
S
V
S
E
Site 23
S232
P
S
A
S
W
Q
N
S
V
S
E
R
P
P
Y
Site 24
S234
A
S
W
Q
N
S
V
S
E
R
P
P
Y
S
Y
Site 25
Y239
S
V
S
E
R
P
P
Y
S
Y
M
A
M
I
Q
Site 26
Y241
S
E
R
P
P
Y
S
Y
M
A
M
I
Q
F
A
Site 27
T252
I
Q
F
A
I
N
S
T
E
R
K
R
M
T
L
Site 28
T258
S
T
E
R
K
R
M
T
L
K
D
I
Y
T
W
Site 29
Y263
R
M
T
L
K
D
I
Y
T
W
I
E
D
H
F
Site 30
S284
A
K
P
G
W
K
N
S
I
R
H
N
L
S
L
Site 31
S290
N
S
I
R
H
N
L
S
L
H
D
M
F
V
R
Site 32
T299
H
D
M
F
V
R
E
T
S
A
N
G
K
V
S
Site 33
S300
D
M
F
V
R
E
T
S
A
N
G
K
V
S
F
Site 34
S306
T
S
A
N
G
K
V
S
F
W
T
I
H
P
S
Site 35
T309
N
G
K
V
S
F
W
T
I
H
P
S
A
N
R
Site 36
Y317
I
H
P
S
A
N
R
Y
L
T
L
D
Q
V
F
Site 37
T319
P
S
A
N
R
Y
L
T
L
D
Q
V
F
K
P
Site 38
S331
F
K
P
L
D
P
G
S
P
Q
L
P
E
H
L
Site 39
S340
Q
L
P
E
H
L
E
S
Q
Q
K
R
P
N
P
Site 40
T354
P
E
L
R
R
N
M
T
I
K
T
E
L
P
L
Site 41
T357
R
R
N
M
T
I
K
T
E
L
P
L
G
A
R
Site 42
S376
P
L
L
P
R
V
S
S
Y
L
V
P
I
Q
F
Site 43
S408
L
A
A
S
L
M
S
S
E
L
A
R
H
S
K
Site 44
S414
S
S
E
L
A
R
H
S
K
R
V
R
I
A
P
Site 45
S434
E
E
G
I
A
P
L
S
S
A
G
P
G
K
E
Site 46
S435
E
G
I
A
P
L
S
S
A
G
P
G
K
E
E
Site 47
S451
L
L
F
G
E
G
F
S
P
L
L
P
V
Q
T
Site 48
S481
A
R
P
I
K
V
E
S
P
P
L
E
E
W
P
Site 49
S489
P
P
L
E
E
W
P
S
P
A
P
S
F
K
E
Site 50
S493
E
W
P
S
P
A
P
S
F
K
E
E
S
S
H
Site 51
S499
P
S
F
K
E
E
S
S
H
S
W
E
D
S
S
Site 52
S501
F
K
E
E
S
S
H
S
W
E
D
S
S
Q
S
Site 53
S505
S
S
H
S
W
E
D
S
S
Q
S
P
T
P
R
Site 54
S506
S
H
S
W
E
D
S
S
Q
S
P
T
P
R
P
Site 55
S508
S
W
E
D
S
S
Q
S
P
T
P
R
P
K
K
Site 56
T510
E
D
S
S
Q
S
P
T
P
R
P
K
K
S
Y
Site 57
S516
P
T
P
R
P
K
K
S
Y
S
G
L
R
S
P
Site 58
S518
P
R
P
K
K
S
Y
S
G
L
R
S
P
T
R
Site 59
S522
K
S
Y
S
G
L
R
S
P
T
R
C
V
S
E
Site 60
T524
Y
S
G
L
R
S
P
T
R
C
V
S
E
M
L
Site 61
S528
R
S
P
T
R
C
V
S
E
M
L
V
I
Q
H
Site 62
S542
H
R
E
R
R
E
R
S
R
S
R
R
K
Q
H
Site 63
S544
E
R
R
E
R
S
R
S
R
R
K
Q
H
L
L
Site 64
S563
D
E
P
E
L
L
F
S
E
G
P
S
T
S
R
Site 65
S567
L
L
F
S
E
G
P
S
T
S
R
W
A
A
E
Site 66
T568
L
F
S
E
G
P
S
T
S
R
W
A
A
E
L
Site 67
S581
E
L
P
F
P
A
D
S
S
D
P
A
S
Q
L
Site 68
S582
L
P
F
P
A
D
S
S
D
P
A
S
Q
L
S
Site 69
S586
A
D
S
S
D
P
A
S
Q
L
S
Y
S
Q
E
Site 70
S589
S
D
P
A
S
Q
L
S
Y
S
Q
E
V
G
G
Site 71
Y590
D
P
A
S
Q
L
S
Y
S
Q
E
V
G
G
P
Site 72
S591
P
A
S
Q
L
S
Y
S
Q
E
V
G
G
P
F
Site 73
T600
E
V
G
G
P
F
K
T
P
I
K
E
T
L
P
Site 74
T605
F
K
T
P
I
K
E
T
L
P
I
S
S
T
P
Site 75
S609
I
K
E
T
L
P
I
S
S
T
P
S
K
S
V
Site 76
S610
K
E
T
L
P
I
S
S
T
P
S
K
S
V
L
Site 77
T611
E
T
L
P
I
S
S
T
P
S
K
S
V
L
P
Site 78
S613
L
P
I
S
S
T
P
S
K
S
V
L
P
R
T
Site 79
S615
I
S
S
T
P
S
K
S
V
L
P
R
T
P
E
Site 80
T620
S
K
S
V
L
P
R
T
P
E
S
W
R
L
T
Site 81
S623
V
L
P
R
T
P
E
S
W
R
L
T
P
P
A
Site 82
T627
T
P
E
S
W
R
L
T
P
P
A
K
V
G
G
Site 83
S638
K
V
G
G
L
D
F
S
P
V
Q
T
S
Q
G
Site 84
T642
L
D
F
S
P
V
Q
T
S
Q
G
A
S
D
P
Site 85
S643
D
F
S
P
V
Q
T
S
Q
G
A
S
D
P
L
Site 86
S647
V
Q
T
S
Q
G
A
S
D
P
L
P
D
P
L
Site 87
T662
G
L
M
D
L
S
T
T
P
L
Q
S
A
P
P
Site 88
S666
L
S
T
T
P
L
Q
S
A
P
P
L
E
S
P
Site 89
S672
Q
S
A
P
P
L
E
S
P
Q
R
L
L
S
S
Site 90
S678
E
S
P
Q
R
L
L
S
S
E
P
L
D
L
I
Site 91
S679
S
P
Q
R
L
L
S
S
E
P
L
D
L
I
S
Site 92
S686
S
E
P
L
D
L
I
S
V
P
F
G
N
S
S
Site 93
S692
I
S
V
P
F
G
N
S
S
P
S
D
I
D
V
Site 94
S693
S
V
P
F
G
N
S
S
P
S
D
I
D
V
P
Site 95
S695
P
F
G
N
S
S
P
S
D
I
D
V
P
K
P
Site 96
S704
I
D
V
P
K
P
G
S
P
E
P
Q
V
S
G
Site 97
S710
G
S
P
E
P
Q
V
S
G
L
A
A
N
R
S
Site 98
S717
S
G
L
A
A
N
R
S
L
T
E
G
L
V
L
Site 99
T719
L
A
A
N
R
S
L
T
E
G
L
V
L
D
T
Site 100
T726
T
E
G
L
V
L
D
T
M
N
D
S
L
S
K
Site 101
S730
V
L
D
T
M
N
D
S
L
S
K
I
L
L
D
Site 102
S732
D
T
M
N
D
S
L
S
K
I
L
L
D
I
S
Site 103
S739
S
K
I
L
L
D
I
S
F
P
G
L
D
E
D
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation