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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PCDH1
Full Name:
Protocadherin-1
Alias:
Cadherin-like 1; Cadherin-like protein 1; Pc42; Protocadherin 1; Protocadherin-42; Similar to protocadherin 1
Type:
Intercellular junction, Plasma membrane, Integral plasma membrane protein
Mass (Da):
114743
Number AA:
1060
UniProt ID:
Q08174
International Prot ID:
IPI00000024
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005911
GO:0005887
Uniprot
OncoNet
Molecular Function:
GO:0005509
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0007267
GO:0007156
GO:0007399
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S29
R
M
E
H
L
R
H
S
P
G
P
G
G
Q
R
Site 2
Y81
I
G
S
L
A
A
D
Y
G
F
P
D
V
G
H
Site 3
T111
K
T
G
D
I
F
T
T
E
T
S
I
D
R
E
Site 4
T113
G
D
I
F
T
T
E
T
S
I
D
R
E
G
L
Site 5
S114
D
I
F
T
T
E
T
S
I
D
R
E
G
L
R
Site 6
T249
R
W
D
S
Y
D
L
T
I
K
V
Q
D
G
G
Site 7
S262
G
G
S
P
P
R
A
S
S
A
L
L
R
V
T
Site 8
S446
P
F
Q
L
R
Q
A
S
E
T
G
S
D
S
K
Site 9
S450
R
Q
A
S
E
T
G
S
D
S
K
K
K
Y
F
Site 10
Y456
G
S
D
S
K
K
K
Y
F
L
Q
T
T
T
P
Site 11
S531
V
I
A
E
I
T
A
S
D
A
D
S
G
S
N
Site 12
S537
A
S
D
A
D
S
G
S
N
A
E
L
V
Y
S
Site 13
S544
S
N
A
E
L
V
Y
S
L
E
P
E
P
A
A
Site 14
S795
H
R
L
V
V
K
V
S
D
R
G
K
P
P
R
Site 15
Y876
A
L
A
V
L
V
R
Y
C
R
Q
R
E
A
K
Site 16
S884
C
R
Q
R
E
A
K
S
G
Y
Q
A
G
K
K
Site 17
Y886
Q
R
E
A
K
S
G
Y
Q
A
G
K
K
E
T
Site 18
Y897
K
K
E
T
K
D
L
Y
A
P
K
P
S
G
K
Site 19
S902
D
L
Y
A
P
K
P
S
G
K
A
S
K
G
N
Site 20
S906
P
K
P
S
G
K
A
S
K
G
N
K
S
K
G
Site 21
S911
K
A
S
K
G
N
K
S
K
G
K
K
S
K
S
Site 22
S916
N
K
S
K
G
K
K
S
K
S
P
K
P
V
K
Site 23
S918
S
K
G
K
K
S
K
S
P
K
P
V
K
P
V
Site 24
S936
D
E
A
G
L
Q
K
S
L
K
F
N
L
M
S
Site 25
S943
S
L
K
F
N
L
M
S
D
A
P
G
D
S
P
Site 26
S949
M
S
D
A
P
G
D
S
P
R
I
H
L
P
L
Site 27
Y958
R
I
H
L
P
L
N
Y
P
P
G
S
P
D
L
Site 28
S962
P
L
N
Y
P
P
G
S
P
D
L
G
R
H
Y
Site 29
Y969
S
P
D
L
G
R
H
Y
R
S
N
S
P
L
P
Site 30
S971
D
L
G
R
H
Y
R
S
N
S
P
L
P
S
I
Site 31
S973
G
R
H
Y
R
S
N
S
P
L
P
S
I
Q
L
Site 32
S977
R
S
N
S
P
L
P
S
I
Q
L
Q
P
Q
S
Site 33
S984
S
I
Q
L
Q
P
Q
S
P
S
A
S
K
K
H
Site 34
S986
Q
L
Q
P
Q
S
P
S
A
S
K
K
H
Q
V
Site 35
S988
Q
P
Q
S
P
S
A
S
K
K
H
Q
V
V
Q
Site 36
T1002
Q
D
L
P
P
A
N
T
F
V
G
T
G
D
T
Site 37
T1009
T
F
V
G
T
G
D
T
T
S
T
G
S
E
Q
Site 38
T1010
F
V
G
T
G
D
T
T
S
T
G
S
E
Q
Y
Site 39
S1011
V
G
T
G
D
T
T
S
T
G
S
E
Q
Y
S
Site 40
S1014
G
D
T
T
S
T
G
S
E
Q
Y
S
D
Y
S
Site 41
Y1017
T
S
T
G
S
E
Q
Y
S
D
Y
S
Y
R
T
Site 42
S1018
S
T
G
S
E
Q
Y
S
D
Y
S
Y
R
T
N
Site 43
Y1020
G
S
E
Q
Y
S
D
Y
S
Y
R
T
N
P
P
Site 44
S1021
S
E
Q
Y
S
D
Y
S
Y
R
T
N
P
P
K
Site 45
Y1022
E
Q
Y
S
D
Y
S
Y
R
T
N
P
P
K
Y
Site 46
T1024
Y
S
D
Y
S
Y
R
T
N
P
P
K
Y
P
S
Site 47
Y1029
Y
R
T
N
P
P
K
Y
P
S
K
Q
V
G
Q
Site 48
S1041
V
G
Q
P
F
Q
L
S
T
P
Q
P
L
P
H
Site 49
T1042
G
Q
P
F
Q
L
S
T
P
Q
P
L
P
H
P
Site 50
Y1050
P
Q
P
L
P
H
P
Y
H
G
A
I
W
T
E
Site 51
T1056
P
Y
H
G
A
I
W
T
E
V
W
E
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation