KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
CYP4F3
Full Name:
Leukotriene-B(4) omega-hydroxylase 2
Alias:
CYPIVF3;Cytochrome P450 4F3;Cytochrome P450-LTB-omega;Leukotriene-B(4) 20-monooxygenase 2
Type:
Mass (Da):
59847
Number AA:
520
UniProt ID:
Q08477
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S70
H
L
G
L
I
H
S
S
E
E
G
L
L
Y
T
Site 2
Y76
S
S
E
E
G
L
L
Y
T
Q
S
L
A
C
T
Site 3
S126
P
K
D
K
V
F
Y
S
F
L
K
P
W
L
G
Site 4
S139
L
G
D
G
L
L
L
S
A
G
E
K
W
S
R
Site 5
S145
L
S
A
G
E
K
W
S
R
H
R
R
M
L
T
Site 6
T152
S
R
H
R
R
M
L
T
P
A
F
H
F
N
I
Site 7
Y163
H
F
N
I
L
K
P
Y
M
K
I
F
N
E
S
Site 8
S186
Q
L
L
A
S
E
G
S
A
R
L
D
M
F
E
Site 9
S209
S
L
Q
K
C
V
F
S
F
D
S
H
C
Q
E
Site 10
S212
K
C
V
F
S
F
D
S
H
C
Q
E
K
P
S
Site 11
Y248
L
Y
I
D
F
L
Y
Y
L
T
P
D
G
Q
R
Site 12
T250
I
D
F
L
Y
Y
L
T
P
D
G
Q
R
F
R
Site 13
T267
C
R
L
V
H
D
F
T
D
A
V
I
Q
E
R
Site 14
T277
V
I
Q
E
R
R
R
T
L
P
S
Q
G
V
D
Site 15
S280
E
R
R
R
T
L
P
S
Q
G
V
D
D
F
L
Site 16
T295
Q
A
K
A
K
S
K
T
L
D
F
I
D
V
L
Site 17
S305
F
I
D
V
L
L
L
S
K
D
E
D
G
K
K
Site 18
S314
D
E
D
G
K
K
L
S
D
E
D
I
R
A
E
Site 19
T324
D
I
R
A
E
A
D
T
F
M
F
E
G
H
D
Site 20
T333
M
F
E
G
H
D
T
T
A
S
G
L
S
W
V
Site 21
S335
E
G
H
D
T
T
A
S
G
L
S
W
V
L
Y
Site 22
Y342
S
G
L
S
W
V
L
Y
H
L
A
K
H
P
E
Site 23
Y350
H
L
A
K
H
P
E
Y
Q
E
R
C
R
Q
E
Site 24
S454
P
K
N
I
K
E
R
S
P
L
A
F
I
P
F
Site 25
T496
F
R
V
L
P
D
H
T
E
P
R
R
K
P
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation