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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SPOCK1
Full Name:
Testican-1
Alias:
Sparc/osteonectin, cwcv and kazal-like domains proteoglycan 1; SPOCK; TESTICAN; TIC1; TICN1
Type:
Extracellular region, Proteinaceous extracellular matrix protein
Mass (Da):
49124
Number AA:
439
UniProt ID:
Q08629
International Prot ID:
IPI00005292
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005578
Uniprot
OncoNet
Molecular Function:
GO:0005509
PhosphoSite+
KinaseNET
Biological Process:
GO:0007155
GO:0008283
GO:0006928
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S46
L
D
N
D
Q
W
L
S
T
V
S
Q
Y
D
R
Site 2
T47
D
N
D
Q
W
L
S
T
V
S
Q
Y
D
R
D
Site 3
S49
D
Q
W
L
S
T
V
S
Q
Y
D
R
D
K
Y
Site 4
Y51
W
L
S
T
V
S
Q
Y
D
R
D
K
Y
W
N
Site 5
Y56
S
Q
Y
D
R
D
K
Y
W
N
R
F
R
D
D
Site 6
Y65
N
R
F
R
D
D
D
Y
F
R
N
W
N
P
N
Site 7
S82
F
D
Q
A
L
D
P
S
K
D
P
C
L
K
V
Site 8
S150
Q
S
A
M
V
C
G
S
D
G
H
S
Y
T
S
Site 9
S154
V
C
G
S
D
G
H
S
Y
T
S
K
C
K
L
Site 10
Y155
C
G
S
D
G
H
S
Y
T
S
K
C
K
L
E
Site 11
T156
G
S
D
G
H
S
Y
T
S
K
C
K
L
E
F
Site 12
S157
S
D
G
H
S
Y
T
S
K
C
K
L
E
F
H
Site 13
S167
K
L
E
F
H
A
C
S
T
G
K
S
L
A
T
Site 14
S171
H
A
C
S
T
G
K
S
L
A
T
L
C
D
G
Site 15
T174
S
T
G
K
S
L
A
T
L
C
D
G
P
C
P
Site 16
S196
P
K
H
K
A
E
R
S
A
C
T
D
K
E
L
Site 17
S208
K
E
L
R
N
L
A
S
R
L
K
D
W
F
G
Site 18
T228
A
N
R
V
I
K
P
T
S
S
N
T
A
Q
G
Site 19
S230
R
V
I
K
P
T
S
S
N
T
A
Q
G
R
F
Site 20
T239
T
A
Q
G
R
F
D
T
S
I
L
P
I
C
K
Site 21
S240
A
Q
G
R
F
D
T
S
I
L
P
I
C
K
D
Site 22
Y260
F
N
K
L
D
M
N
Y
D
L
L
L
D
P
S
Site 23
Y273
P
S
E
I
N
A
I
Y
L
D
K
Y
E
P
C
Site 24
Y277
N
A
I
Y
L
D
K
Y
E
P
C
I
K
P
L
Site 25
S290
P
L
F
N
S
C
D
S
F
K
D
G
K
L
S
Site 26
S324
M
N
R
I
Q
K
L
S
K
G
K
S
L
L
G
Site 27
S328
Q
K
L
S
K
G
K
S
L
L
G
A
F
I
P
Site 28
Y342
P
R
C
N
E
E
G
Y
Y
K
A
T
Q
C
H
Site 29
Y343
R
C
N
E
E
G
Y
Y
K
A
T
Q
C
H
G
Site 30
T346
E
E
G
Y
Y
K
A
T
Q
C
H
G
S
T
G
Site 31
S351
K
A
T
Q
C
H
G
S
T
G
Q
C
W
C
V
Site 32
T352
A
T
Q
C
H
G
S
T
G
Q
C
W
C
V
D
Site 33
Y361
Q
C
W
C
V
D
K
Y
G
N
E
L
A
G
S
Site 34
S368
Y
G
N
E
L
A
G
S
R
K
Q
G
A
V
S
Site 35
S375
S
R
K
Q
G
A
V
S
C
E
E
E
Q
E
T
Site 36
T382
S
C
E
E
E
Q
E
T
S
G
D
F
G
S
G
Site 37
S383
C
E
E
E
Q
E
T
S
G
D
F
G
S
G
G
Site 38
Y400
V
L
L
D
D
L
E
Y
E
R
E
L
G
P
K
Site 39
T417
E
G
K
L
R
V
H
T
R
A
V
T
E
D
D
Site 40
T421
R
V
H
T
R
A
V
T
E
D
D
E
D
E
D
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation