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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SSRP1
Full Name:
FACT complex subunit SSRP1
Alias:
Chromatin-specific transcription elongation factor 80 kDa subunit; Chromatin-specific transcription elongation factor 80 KDA subunit; CIIDBP; Facilitates chromatin remodeling 80 kDa subunit; Facilitates chromatin transcription complex subunit SSRP1; FACT 80 kDa subunit; FACT 80 KDA subunit; FACT80; FACTp80; HSSRP1; Recombination signal sequence recognition protein; SSRP; Structure specific recognition protein 1; Structure-specific recognition protein 1; T160
Type:
Transcription initiation complex; Transcription, coactivator/corepressor
Mass (Da):
81075
Number AA:
709
UniProt ID:
Q08945
International Prot ID:
IPI00005154
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0000785
GO:0005634
GO:0005654
Uniprot
OncoNet
Molecular Function:
GO:0003676
GO:0003677
GO:0005488
PhosphoSite+
KinaseNET
Biological Process:
GO:0006139
GO:0006259
GO:0006260
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y11
T
L
E
F
N
D
V
Y
Q
E
V
K
G
S
M
Site 2
S17
V
Y
Q
E
V
K
G
S
M
N
D
G
R
L
R
Site 3
S26
N
D
G
R
L
R
L
S
R
Q
G
I
I
F
K
Site 4
T66
G
H
G
L
K
L
L
T
K
N
G
H
V
Y
K
Site 5
Y72
L
T
K
N
G
H
V
Y
K
Y
D
G
F
R
E
Site 6
Y74
K
N
G
H
V
Y
K
Y
D
G
F
R
E
S
E
Site 7
S80
K
Y
D
G
F
R
E
S
E
F
E
K
L
S
D
Site 8
S86
E
S
E
F
E
K
L
S
D
F
F
K
T
H
Y
Site 9
T91
K
L
S
D
F
F
K
T
H
Y
R
L
E
L
M
Site 10
Y93
S
D
F
F
K
T
H
Y
R
L
E
L
M
E
K
Site 11
S120
K
F
G
G
Q
L
L
S
F
D
I
G
D
Q
P
Site 12
S137
E
I
P
L
S
N
V
S
Q
C
T
T
G
K
N
Site 13
T141
S
N
V
S
Q
C
T
T
G
K
N
E
V
T
L
Site 14
S159
Q
N
D
D
A
E
V
S
L
M
E
V
R
F
Y
Site 15
Y166
S
L
M
E
V
R
F
Y
V
P
P
T
Q
E
D
Site 16
T170
V
R
F
Y
V
P
P
T
Q
E
D
G
V
D
P
Site 17
T209
F
R
E
L
Q
C
L
T
P
R
G
R
Y
D
I
Site 18
Y214
C
L
T
P
R
G
R
Y
D
I
R
I
Y
P
T
Site 19
Y219
G
R
Y
D
I
R
I
Y
P
T
F
L
H
L
H
Site 20
T229
F
L
H
L
H
G
K
T
F
D
Y
K
I
P
Y
Site 21
Y232
L
H
G
K
T
F
D
Y
K
I
P
Y
T
T
V
Site 22
S258
R
Q
M
F
F
V
I
S
L
D
P
P
I
K
Q
Site 23
Y270
I
K
Q
G
Q
T
R
Y
H
F
L
I
L
L
F
Site 24
S278
H
F
L
I
L
L
F
S
K
D
E
D
I
S
L
Site 25
S284
F
S
K
D
E
D
I
S
L
T
L
N
M
N
E
Site 26
T286
K
D
E
D
I
S
L
T
L
N
M
N
E
E
E
Site 27
T303
K
R
F
E
G
R
L
T
K
N
M
S
G
S
L
Site 28
S307
G
R
L
T
K
N
M
S
G
S
L
Y
E
M
V
Site 29
S309
L
T
K
N
M
S
G
S
L
Y
E
M
V
S
R
Site 30
Y311
K
N
M
S
G
S
L
Y
E
M
V
S
R
V
M
Site 31
T327
A
L
V
N
R
K
I
T
V
P
G
N
F
Q
G
Site 32
T342
H
S
G
A
Q
C
I
T
C
S
Y
K
A
S
S
Site 33
Y361
P
L
E
R
G
F
I
Y
V
H
K
P
P
V
H
Site 34
T383
F
V
N
F
A
R
G
T
T
T
T
R
S
F
D
Site 35
T384
V
N
F
A
R
G
T
T
T
T
R
S
F
D
F
Site 36
T385
N
F
A
R
G
T
T
T
T
R
S
F
D
F
E
Site 37
T386
F
A
R
G
T
T
T
T
R
S
F
D
F
E
I
Site 38
S388
R
G
T
T
T
T
R
S
F
D
F
E
I
E
T
Site 39
T399
E
I
E
T
K
Q
G
T
Q
Y
T
F
S
S
I
Site 40
Y401
E
T
K
Q
G
T
Q
Y
T
F
S
S
I
E
R
Site 41
T402
T
K
Q
G
T
Q
Y
T
F
S
S
I
E
R
E
Site 42
S404
Q
G
T
Q
Y
T
F
S
S
I
E
R
E
E
Y
Site 43
S405
G
T
Q
Y
T
F
S
S
I
E
R
E
E
Y
G
Site 44
Y411
S
S
I
E
R
E
E
Y
G
K
L
F
D
F
V
Site 45
S437
L
K
E
G
M
N
P
S
Y
D
E
Y
A
D
S
Site 46
Y438
K
E
G
M
N
P
S
Y
D
E
Y
A
D
S
D
Site 47
Y441
M
N
P
S
Y
D
E
Y
A
D
S
D
E
D
Q
Site 48
S444
S
Y
D
E
Y
A
D
S
D
E
D
Q
H
D
A
Site 49
Y452
D
E
D
Q
H
D
A
Y
L
E
R
M
K
E
E
Site 50
S470
R
E
E
N
A
N
D
S
S
D
D
S
G
E
E
Site 51
S471
E
E
N
A
N
D
S
S
D
D
S
G
E
E
T
Site 52
S474
A
N
D
S
S
D
D
S
G
E
E
T
D
E
S
Site 53
T478
S
D
D
S
G
E
E
T
D
E
S
F
N
P
G
Site 54
S481
S
G
E
E
T
D
E
S
F
N
P
G
E
E
E
Site 55
S497
D
V
A
E
E
F
D
S
N
A
S
A
S
S
S
Site 56
S500
E
E
F
D
S
N
A
S
A
S
S
S
S
N
E
Site 57
S502
F
D
S
N
A
S
A
S
S
S
S
N
E
G
D
Site 58
S504
S
N
A
S
A
S
S
S
S
N
E
G
D
S
D
Site 59
S505
N
A
S
A
S
S
S
S
N
E
G
D
S
D
R
Site 60
S510
S
S
S
N
E
G
D
S
D
R
D
E
K
K
R
Site 61
S531
K
M
A
K
D
R
K
S
R
K
K
P
V
E
V
Site 62
Y554
P
K
R
P
M
S
A
Y
M
L
W
L
N
A
S
Site 63
S561
Y
M
L
W
L
N
A
S
R
E
K
I
K
S
D
Site 64
S567
A
S
R
E
K
I
K
S
D
H
P
G
I
S
I
Site 65
S573
K
S
D
H
P
G
I
S
I
T
D
L
S
K
K
Site 66
S578
G
I
S
I
T
D
L
S
K
K
A
G
E
I
W
Site 67
Y607
A
E
D
A
R
R
D
Y
E
K
A
M
K
E
Y
Site 68
S621
Y
E
G
G
R
G
E
S
S
K
R
D
K
S
K
Site 69
S622
E
G
G
R
G
E
S
S
K
R
D
K
S
K
K
Site 70
S627
E
S
S
K
R
D
K
S
K
K
K
K
K
V
K
Site 71
S641
K
V
K
M
E
K
K
S
T
P
S
R
G
S
S
Site 72
T642
V
K
M
E
K
K
S
T
P
S
R
G
S
S
S
Site 73
S644
M
E
K
K
S
T
P
S
R
G
S
S
S
K
S
Site 74
S647
K
S
T
P
S
R
G
S
S
S
K
S
S
S
R
Site 75
S648
S
T
P
S
R
G
S
S
S
K
S
S
S
R
Q
Site 76
S649
T
P
S
R
G
S
S
S
K
S
S
S
R
Q
L
Site 77
S651
S
R
G
S
S
S
K
S
S
S
R
Q
L
S
E
Site 78
S652
R
G
S
S
S
K
S
S
S
R
Q
L
S
E
S
Site 79
S653
G
S
S
S
K
S
S
S
R
Q
L
S
E
S
F
Site 80
S657
K
S
S
S
R
Q
L
S
E
S
F
K
S
K
E
Site 81
S659
S
S
R
Q
L
S
E
S
F
K
S
K
E
F
V
Site 82
S662
Q
L
S
E
S
F
K
S
K
E
F
V
S
S
D
Site 83
S667
F
K
S
K
E
F
V
S
S
D
E
S
S
S
G
Site 84
S668
K
S
K
E
F
V
S
S
D
E
S
S
S
G
E
Site 85
S671
E
F
V
S
S
D
E
S
S
S
G
E
N
K
S
Site 86
S672
F
V
S
S
D
E
S
S
S
G
E
N
K
S
K
Site 87
S673
V
S
S
D
E
S
S
S
G
E
N
K
S
K
K
Site 88
S678
S
S
S
G
E
N
K
S
K
K
K
R
R
R
S
Site 89
S685
S
K
K
K
R
R
R
S
E
D
S
E
E
E
E
Site 90
S688
K
R
R
R
S
E
D
S
E
E
E
E
L
A
S
Site 91
S695
S
E
E
E
E
L
A
S
T
P
P
S
S
E
D
Site 92
T696
E
E
E
E
L
A
S
T
P
P
S
S
E
D
S
Site 93
S699
E
L
A
S
T
P
P
S
S
E
D
S
A
S
G
Site 94
S700
L
A
S
T
P
P
S
S
E
D
S
A
S
G
S
Site 95
S703
T
P
P
S
S
E
D
S
A
S
G
S
D
E
_
Site 96
S705
P
S
S
E
D
S
A
S
G
S
D
E
_
_
_
Site 97
S707
S
E
D
S
A
S
G
S
D
E
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation