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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ZNF616
Full Name:
Zinc finger protein 616
Alias:
Type:
Mass (Da):
90273
Number AA:
781
UniProt ID:
Q08AN1
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S17
K
D
V
A
I
E
F
S
Q
E
E
W
K
C
L
Site 2
Y32
E
P
V
Q
K
A
L
Y
K
D
V
M
L
E
N
Site 3
T60
V
I
K
E
L
P
P
T
E
N
S
N
T
G
E
Site 4
T65
P
P
T
E
N
S
N
T
G
E
R
F
Q
T
V
Site 5
T71
N
T
G
E
R
F
Q
T
V
A
L
E
R
H
Q
Site 6
S79
V
A
L
E
R
H
Q
S
Y
D
I
E
N
L
Y
Site 7
Y86
S
Y
D
I
E
N
L
Y
F
R
E
I
Q
K
H
Site 8
T120
V
P
H
E
N
N
L
T
G
K
R
D
Q
H
S
Site 9
S127
T
G
K
R
D
Q
H
S
Q
G
D
V
E
N
N
Site 10
T141
N
H
I
E
N
Q
L
T
S
N
F
E
S
R
L
Site 11
S146
Q
L
T
S
N
F
E
S
R
L
A
E
L
Q
K
Site 12
Y161
V
Q
T
E
G
R
L
Y
E
C
N
E
T
E
K
Site 13
T166
R
L
Y
E
C
N
E
T
E
K
T
G
N
N
G
Site 14
T169
E
C
N
E
T
E
K
T
G
N
N
G
C
L
V
Site 15
S177
G
N
N
G
C
L
V
S
P
H
I
R
E
K
T
Site 16
T184
S
P
H
I
R
E
K
T
Y
V
C
N
E
C
G
Site 17
Y185
P
H
I
R
E
K
T
Y
V
C
N
E
C
G
K
Site 18
S197
C
G
K
A
F
K
A
S
S
S
L
I
N
H
Q
Site 19
S198
G
K
A
F
K
A
S
S
S
L
I
N
H
Q
R
Site 20
S199
K
A
F
K
A
S
S
S
L
I
N
H
Q
R
I
Site 21
T208
I
N
H
Q
R
I
H
T
T
E
K
P
Y
K
C
Site 22
Y213
I
H
T
T
E
K
P
Y
K
C
N
E
C
G
K
Site 23
Y241
V
H
T
R
G
K
S
Y
Q
C
D
V
C
G
K
Site 24
S254
G
K
I
F
R
K
N
S
Y
F
V
R
H
Q
R
Site 25
Y255
K
I
F
R
K
N
S
Y
F
V
R
H
Q
R
S
Site 26
T264
V
R
H
Q
R
S
H
T
G
Q
K
P
Y
I
C
Site 27
Y269
S
H
T
G
Q
K
P
Y
I
C
N
E
C
G
K
Site 28
S277
I
C
N
E
C
G
K
S
F
S
K
S
S
H
L
Site 29
S279
N
E
C
G
K
S
F
S
K
S
S
H
L
A
V
Site 30
S281
C
G
K
S
F
S
K
S
S
H
L
A
V
H
Q
Site 31
T292
A
V
H
Q
R
I
H
T
G
E
K
P
Y
K
C
Site 32
S307
N
L
C
G
K
S
F
S
Q
R
V
H
L
R
L
Site 33
T317
V
H
L
R
L
H
Q
T
V
H
T
G
E
R
P
Site 34
T333
K
C
N
E
C
G
K
T
F
K
R
S
S
N
L
Site 35
S338
G
K
T
F
K
R
S
S
N
L
T
V
H
Q
V
Site 36
T341
F
K
R
S
S
N
L
T
V
H
Q
V
I
H
A
Site 37
S366
G
K
A
F
R
H
R
S
N
L
V
C
H
R
R
Site 38
Y381
I
H
S
G
E
K
Q
Y
K
C
N
E
C
G
K
Site 39
S391
N
E
C
G
K
V
F
S
K
R
S
S
L
A
V
Site 40
S395
K
V
F
S
K
R
S
S
L
A
V
H
R
R
I
Site 41
T404
A
V
H
R
R
I
H
T
V
E
K
P
C
K
C
Site 42
S423
K
V
F
S
K
R
S
S
L
A
V
H
Q
R
I
Site 43
T432
A
V
H
Q
R
I
H
T
G
Q
K
T
Y
K
C
Site 44
T460
A
V
H
W
R
I
H
T
G
E
K
A
Y
K
C
Site 45
Y465
I
H
T
G
E
K
A
Y
K
C
N
E
C
G
K
Site 46
S475
N
E
C
G
K
V
F
S
I
H
S
R
L
A
A
Site 47
T488
A
A
H
Q
R
I
H
T
G
E
K
P
Y
K
C
Site 48
Y493
I
H
T
G
E
K
P
Y
K
C
N
E
C
G
K
Site 49
S503
N
E
C
G
K
V
F
S
Q
H
S
R
L
A
V
Site 50
T516
A
V
H
R
R
I
H
T
G
E
K
P
Y
K
C
Site 51
Y521
I
H
T
G
E
K
P
Y
K
C
K
E
C
G
K
Site 52
S531
K
E
C
G
K
V
F
S
D
R
S
A
F
A
R
Site 53
S534
G
K
V
F
S
D
R
S
A
F
A
R
H
R
R
Site 54
T544
A
R
H
R
R
I
H
T
G
E
K
P
Y
K
C
Site 55
S559
K
E
C
G
K
V
F
S
Q
C
S
R
L
T
V
Site 56
T565
F
S
Q
C
S
R
L
T
V
H
R
R
I
H
S
Site 57
S572
T
V
H
R
R
I
H
S
G
E
K
P
Y
K
C
Site 58
Y577
I
H
S
G
E
K
P
Y
K
C
N
E
C
G
K
Site 59
S587
N
E
C
G
K
V
Y
S
Q
Y
S
H
L
V
G
Site 60
Y589
C
G
K
V
Y
S
Q
Y
S
H
L
V
G
H
R
Site 61
S590
G
K
V
Y
S
Q
Y
S
H
L
V
G
H
R
R
Site 62
T600
V
G
H
R
R
V
H
T
G
E
K
P
Y
K
C
Site 63
Y605
V
H
T
G
E
K
P
Y
K
C
H
E
C
G
K
Site 64
S618
G
K
A
F
N
Q
G
S
T
L
N
R
H
Q
R
Site 65
T628
N
R
H
Q
R
I
H
T
G
E
K
P
Y
K
C
Site 66
S643
N
Q
C
G
N
S
F
S
Q
R
V
H
L
R
L
Site 67
T653
V
H
L
R
L
H
Q
T
V
H
T
G
D
R
P
Site 68
Y661
V
H
T
G
D
R
P
Y
K
C
N
E
C
G
K
Site 69
S674
G
K
T
F
K
R
S
S
N
L
T
A
H
Q
I
Site 70
T677
F
K
R
S
S
N
L
T
A
H
Q
I
I
H
A
Site 71
Y689
I
H
A
G
K
K
P
Y
K
C
D
E
C
G
K
Site 72
S701
C
G
K
V
F
R
H
S
S
H
L
V
S
H
Q
Site 73
S702
G
K
V
F
R
H
S
S
H
L
V
S
H
Q
R
Site 74
S706
R
H
S
S
H
L
V
S
H
Q
R
I
H
T
G
Site 75
T712
V
S
H
Q
R
I
H
T
G
E
K
R
Y
K
C
Site 76
Y717
I
H
T
G
E
K
R
Y
K
C
I
E
C
G
K
Site 77
S731
K
A
F
G
R
L
F
S
L
S
K
H
Q
R
I
Site 78
S733
F
G
R
L
F
S
L
S
K
H
Q
R
I
H
S
Site 79
S740
S
K
H
Q
R
I
H
S
G
K
K
P
Y
K
C
Site 80
Y745
I
H
S
G
K
K
P
Y
K
C
N
E
C
G
K
Site 81
S758
G
K
S
F
I
C
R
S
G
L
T
K
H
R
I
Site 82
T768
T
K
H
R
I
R
H
T
G
E
S
L
T
T
K
Site 83
S771
R
I
R
H
T
G
E
S
L
T
T
K
L
N
V
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation