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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
DMWD
Full Name:
Dystrophia myotonica WD repeat-containing protein
Alias:
D19S593E; DM9; DMR-N9; DMR-N9 protein; Dystrophia myotonica, WD repeat containing; Dystrophia myotonica-containing WD repeat motif protein; Gene59; Protein 59
Type:
Mass (Da):
70438
Number AA:
674
UniProt ID:
Q09019
International Prot ID:
IPI00796018
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
GO:0007126
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S10
A
G
G
A
E
G
G
S
G
P
G
A
A
M
G
Site 2
S24
G
D
C
A
E
I
K
S
Q
F
R
T
R
E
G
Site 3
T28
E
I
K
S
Q
F
R
T
R
E
G
F
Y
K
L
Site 4
S45
G
D
G
A
A
R
R
S
G
P
A
S
A
Q
T
Site 5
S49
A
R
R
S
G
P
A
S
A
Q
T
P
V
P
P
Site 6
T52
S
G
P
A
S
A
Q
T
P
V
P
P
Q
P
P
Site 7
S67
Q
P
P
P
G
P
A
S
A
S
G
P
G
A
A
Site 8
S69
P
P
G
P
A
S
A
S
G
P
G
A
A
G
P
Site 9
S78
P
G
A
A
G
P
A
S
S
P
P
P
A
G
P
Site 10
S79
G
A
A
G
P
A
S
S
P
P
P
A
G
P
G
Site 11
S106
V
R
L
G
E
P
D
S
A
G
A
G
E
P
P
Site 12
T115
G
A
G
E
P
P
A
T
P
A
G
L
G
S
G
Site 13
Y135
F
N
L
G
R
E
L
Y
F
Y
P
G
C
C
R
Site 14
Y137
L
G
R
E
L
Y
F
Y
P
G
C
C
R
R
G
Site 15
S145
P
G
C
C
R
R
G
S
Q
R
S
I
D
L
N
Site 16
S148
C
R
R
G
S
Q
R
S
I
D
L
N
K
P
I
Site 17
Y160
K
P
I
D
K
R
I
Y
K
G
T
Q
P
T
C
Site 18
T201
L
D
L
I
K
K
D
T
S
K
L
F
N
E
E
Site 19
S202
D
L
I
K
K
D
T
S
K
L
F
N
E
E
R
Site 20
T214
E
E
R
L
I
D
K
T
K
V
T
Y
L
K
W
Site 21
S225
Y
L
K
W
L
P
E
S
E
S
L
F
L
A
S
Site 22
S227
K
W
L
P
E
S
E
S
L
F
L
A
S
H
A
Site 23
S232
S
E
S
L
F
L
A
S
H
A
S
G
H
L
Y
Site 24
Y239
S
H
A
S
G
H
L
Y
L
Y
N
V
S
H
P
Site 25
Y241
A
S
G
H
L
Y
L
Y
N
V
S
H
P
C
A
Site 26
S249
N
V
S
H
P
C
A
S
A
P
P
Q
Y
S
L
Site 27
S255
A
S
A
P
P
Q
Y
S
L
L
K
Q
G
E
G
Site 28
S264
L
K
Q
G
E
G
F
S
V
Y
A
A
K
S
K
Site 29
Y266
Q
G
E
G
F
S
V
Y
A
A
K
S
K
A
P
Site 30
S293
P
L
N
E
F
A
F
S
P
D
G
R
H
L
A
Site 31
Y340
C
W
S
P
D
G
R
Y
V
V
T
G
G
E
D
Site 32
T351
G
G
E
D
D
L
V
T
V
W
S
F
T
E
G
Site 33
Y379
N
A
V
A
F
D
P
Y
T
T
R
A
E
E
A
Site 34
T380
A
V
A
F
D
P
Y
T
T
R
A
E
E
A
A
Site 35
T410
E
E
P
E
A
A
G
T
G
S
A
G
G
A
P
Site 36
S412
P
E
A
A
G
T
G
S
A
G
G
A
P
L
S
Site 37
S419
S
A
G
G
A
P
L
S
P
L
P
K
A
G
S
Site 38
S426
S
P
L
P
K
A
G
S
I
T
Y
R
F
G
S
Site 39
T428
L
P
K
A
G
S
I
T
Y
R
F
G
S
A
G
Site 40
S433
S
I
T
Y
R
F
G
S
A
G
Q
D
T
Q
F
Site 41
Y451
D
L
T
E
D
V
L
Y
P
H
P
P
L
A
R
Site 42
T459
P
H
P
P
L
A
R
T
R
T
L
P
G
T
P
Site 43
T461
P
P
L
A
R
T
R
T
L
P
G
T
P
G
T
Site 44
T465
R
T
R
T
L
P
G
T
P
G
T
T
P
P
A
Site 45
T468
T
L
P
G
T
P
G
T
T
P
P
A
A
S
S
Site 46
T469
L
P
G
T
P
G
T
T
P
P
A
A
S
S
S
Site 47
S474
G
T
T
P
P
A
A
S
S
S
R
G
G
E
P
Site 48
S475
T
T
P
P
A
A
S
S
S
R
G
G
E
P
G
Site 49
S476
T
P
P
A
A
S
S
S
R
G
G
E
P
G
P
Site 50
S489
G
P
G
P
L
P
R
S
L
S
R
S
N
S
L
Site 51
S491
G
P
L
P
R
S
L
S
R
S
N
S
L
P
H
Site 52
S493
L
P
R
S
L
S
R
S
N
S
L
P
H
P
A
Site 53
S495
R
S
L
S
R
S
N
S
L
P
H
P
A
G
G
Site 54
T525
F
S
I
G
R
F
A
T
L
T
L
Q
E
R
R
Site 55
T527
I
G
R
F
A
T
L
T
L
Q
E
R
R
D
R
Site 56
Y543
A
E
K
E
H
K
R
Y
H
S
L
G
N
I
S
Site 57
S545
K
E
H
K
R
Y
H
S
L
G
N
I
S
R
G
Site 58
S550
Y
H
S
L
G
N
I
S
R
G
G
S
G
G
S
Site 59
S554
G
N
I
S
R
G
G
S
G
G
S
G
S
G
G
Site 60
S557
S
R
G
G
S
G
G
S
G
S
G
G
E
K
P
Site 61
S559
G
G
S
G
G
S
G
S
G
G
E
K
P
S
G
Site 62
S565
G
S
G
G
E
K
P
S
G
P
V
P
R
S
R
Site 63
S571
P
S
G
P
V
P
R
S
R
L
D
P
A
K
V
Site 64
T640
K
A
F
T
D
E
E
T
E
A
Q
T
G
E
G
Site 65
S648
E
A
Q
T
G
E
G
S
W
P
R
S
P
S
K
Site 66
S652
G
E
G
S
W
P
R
S
P
S
K
S
V
V
E
Site 67
S654
G
S
W
P
R
S
P
S
K
S
V
V
E
G
I
Site 68
S656
W
P
R
S
P
S
K
S
V
V
E
G
I
S
S
Site 69
S662
K
S
V
V
E
G
I
S
S
Q
P
G
N
S
P
Site 70
S663
S
V
V
E
G
I
S
S
Q
P
G
N
S
P
S
Site 71
S668
I
S
S
Q
P
G
N
S
P
S
G
T
V
V
_
Site 72
S670
S
Q
P
G
N
S
P
S
G
T
V
V
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation