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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
NCBP1
Full Name:
Nuclear cap-binding protein subunit 1
Alias:
80 kDa nuclear cap-binding protein; CBP80; MGC2087; NCBP; NCBP 80 kDa subunit; Nuclear cap binding protein subunit 1, 80kDa
Type:
RNA processing protein
Mass (Da):
91839
Number AA:
790
UniProt ID:
Q09161
International Prot ID:
IPI00019380
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005829
GO:0005845
GO:0005654
Uniprot
OncoNet
Molecular Function:
GO:0000339
GO:0005515
GO:0003723
PhosphoSite+
KinaseNET
Biological Process:
GO:0006370
GO:0006379
GO:0006406
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S7
_
M
S
R
R
R
H
S
D
E
N
D
G
G
Q
Site 2
T21
Q
P
H
K
R
R
K
T
S
D
A
N
E
T
E
Site 3
S22
P
H
K
R
R
K
T
S
D
A
N
E
T
E
D
Site 4
T27
K
T
S
D
A
N
E
T
E
D
H
L
E
S
L
Site 5
S33
E
T
E
D
H
L
E
S
L
I
C
K
V
G
E
Site 6
S42
I
C
K
V
G
E
K
S
A
C
S
L
E
S
N
Site 7
S45
V
G
E
K
S
A
C
S
L
E
S
N
L
E
G
Site 8
S48
K
S
A
C
S
L
E
S
N
L
E
G
L
A
G
Site 9
Y64
L
E
A
D
L
P
N
Y
K
S
K
I
L
R
L
Site 10
S66
A
D
L
P
N
Y
K
S
K
I
L
R
L
L
C
Site 11
Y98
G
L
L
N
A
R
N
Y
N
F
G
G
E
F
V
Site 12
S115
M
I
R
Q
L
K
E
S
L
K
A
N
N
Y
N
Site 13
Y121
E
S
L
K
A
N
N
Y
N
E
A
V
Y
L
V
Site 14
Y126
N
N
Y
N
E
A
V
Y
L
V
R
F
L
S
D
Site 15
S154
A
M
F
E
N
F
V
S
V
T
Q
E
E
D
V
Site 16
Y169
P
Q
V
R
R
D
W
Y
V
Y
A
F
L
S
S
Site 17
Y171
V
R
R
D
W
Y
V
Y
A
F
L
S
S
L
P
Site 18
Y185
P
W
V
G
K
E
L
Y
E
K
K
D
A
E
M
Site 19
T199
M
D
R
I
F
A
N
T
E
S
Y
L
K
R
R
Site 20
T209
Y
L
K
R
R
Q
K
T
H
V
P
M
L
Q
V
Site 21
Y228
K
P
H
P
Q
E
E
Y
L
D
C
L
W
A
Q
Site 22
T272
Q
H
N
L
P
P
F
T
P
P
P
H
T
E
D
Site 23
T277
P
F
T
P
P
P
H
T
E
D
S
V
Y
P
M
Site 24
S280
P
P
P
H
T
E
D
S
V
Y
P
M
P
R
V
Site 25
Y282
P
H
T
E
D
S
V
Y
P
M
P
R
V
I
F
Site 26
Y294
V
I
F
R
M
F
D
Y
T
D
D
P
E
G
P
Site 27
T295
I
F
R
M
F
D
Y
T
D
D
P
E
G
P
V
Site 28
S306
E
G
P
V
M
P
G
S
H
S
V
E
R
F
V
Site 29
S308
P
V
M
P
G
S
H
S
V
E
R
F
V
I
E
Site 30
T331
S
H
W
K
E
R
K
T
C
A
A
Q
L
V
S
Site 31
Y339
C
A
A
Q
L
V
S
Y
P
G
K
N
K
I
P
Site 32
Y399
A
Q
A
T
E
M
L
Y
M
R
L
D
T
M
N
Site 33
S438
E
D
W
S
D
C
L
S
Q
D
P
E
S
P
K
Site 34
S443
C
L
S
Q
D
P
E
S
P
K
P
K
F
V
R
Site 35
Y461
E
K
C
M
R
L
S
Y
H
Q
R
I
L
D
I
Site 36
Y487
N
P
T
C
I
Y
K
Y
G
D
E
S
S
N
S
Site 37
S491
I
Y
K
Y
G
D
E
S
S
N
S
L
P
G
H
Site 38
S492
Y
K
Y
G
D
E
S
S
N
S
L
P
G
H
S
Site 39
S494
Y
G
D
E
S
S
N
S
L
P
G
H
S
V
A
Site 40
S538
D
D
D
D
E
G
F
S
F
N
P
L
K
I
E
Site 41
S564
K
S
F
S
H
S
F
S
A
L
A
K
F
H
E
Site 42
T575
K
F
H
E
V
F
K
T
L
A
E
S
D
E
G
Site 43
S579
V
F
K
T
L
A
E
S
D
E
G
K
L
H
V
Site 44
T611
L
V
D
K
M
I
R
T
Q
I
V
D
C
A
A
Site 45
S625
A
V
A
N
W
I
F
S
S
E
L
S
R
D
F
Site 46
S629
W
I
F
S
S
E
L
S
R
D
F
T
R
L
F
Site 47
T633
S
E
L
S
R
D
F
T
R
L
F
V
W
E
I
Site 48
S643
F
V
W
E
I
L
H
S
T
I
R
K
M
N
K
Site 49
T644
V
W
E
I
L
H
S
T
I
R
K
M
N
K
H
Site 50
S674
A
R
Q
H
K
R
R
S
D
D
D
D
R
S
S
Site 51
S680
R
S
D
D
D
D
R
S
S
D
R
K
D
G
V
Site 52
S681
S
D
D
D
D
R
S
S
D
R
K
D
G
V
L
Site 53
S704
E
K
V
E
S
A
Q
S
E
Q
K
N
L
F
L
Site 54
T730
E
H
L
V
R
C
E
T
D
G
T
S
V
L
T
Site 55
T733
V
R
C
E
T
D
G
T
S
V
L
T
P
W
Y
Site 56
T737
T
D
G
T
S
V
L
T
P
W
Y
K
N
C
I
Site 57
Y740
T
S
V
L
T
P
W
Y
K
N
C
I
E
R
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation