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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
AHNAK
Full Name:
Neuroblast differentiation-associated protein AHNAK
Alias:
AHNAK nucleoprotein; AHNK; Desmoyokin; Desmoyokin;PM227; MGC5395; Neuroblast differentiation associated protein AHNAK; PM227
Type:
Actin binding protein; Cytoskeletal protein; Adaptor/scaffold
Mass (Da):
629101
Number AA:
5890
UniProt ID:
Q09666
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0007399
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T6
_
_
M
E
K
E
E
T
T
R
E
L
L
L
P
Site 2
T7
_
M
E
K
E
E
T
T
R
E
L
L
L
P
N
Site 3
S18
L
L
P
N
W
Q
G
S
G
S
H
G
L
T
I
Site 4
T24
G
S
G
S
H
G
L
T
I
A
Q
R
D
D
G
Site 5
T38
G
V
F
V
Q
E
V
T
Q
N
S
P
A
A
R
Site 6
S41
V
Q
E
V
T
Q
N
S
P
A
A
R
T
G
V
Site 7
T71
N
L
Q
S
G
E
V
T
Q
L
L
N
T
M
G
Site 8
T81
L
N
T
M
G
H
H
T
V
G
L
K
L
H
R
Site 9
S93
L
H
R
K
G
D
R
S
P
E
P
G
Q
T
W
Site 10
T99
R
S
P
E
P
G
Q
T
W
T
R
E
V
F
S
Site 11
T101
P
E
P
G
Q
T
W
T
R
E
V
F
S
S
C
Site 12
S106
T
W
T
R
E
V
F
S
S
C
S
S
E
V
V
Site 13
S107
W
T
R
E
V
F
S
S
C
S
S
E
V
V
L
Site 14
S115
C
S
S
E
V
V
L
S
G
D
D
E
E
Y
Q
Site 15
Y121
L
S
G
D
D
E
E
Y
Q
R
I
Y
T
T
K
Site 16
Y125
D
E
E
Y
Q
R
I
Y
T
T
K
I
K
P
R
Site 17
T126
E
E
Y
Q
R
I
Y
T
T
K
I
K
P
R
L
Site 18
S135
K
I
K
P
R
L
K
S
E
D
G
V
E
G
D
Site 19
S148
G
D
L
G
E
T
Q
S
R
T
I
T
V
T
R
Site 20
T152
E
T
Q
S
R
T
I
T
V
T
R
R
V
T
A
Site 21
T154
Q
S
R
T
I
T
V
T
R
R
V
T
A
Y
T
Site 22
T158
I
T
V
T
R
R
V
T
A
Y
T
V
D
V
T
Site 23
Y160
V
T
R
R
V
T
A
Y
T
V
D
V
T
G
R
Site 24
T161
T
R
R
V
T
A
Y
T
V
D
V
T
G
R
E
Site 25
T165
T
A
Y
T
V
D
V
T
G
R
E
G
A
K
D
Site 26
S176
G
A
K
D
I
D
I
S
S
P
E
F
K
I
K
Site 27
S177
A
K
D
I
D
I
S
S
P
E
F
K
I
K
I
Site 28
T199
I
S
N
V
D
V
E
T
Q
S
G
K
T
V
I
Site 29
T204
V
E
T
Q
S
G
K
T
V
I
R
L
P
S
G
Site 30
S210
K
T
V
I
R
L
P
S
G
S
G
A
A
S
P
Site 31
S212
V
I
R
L
P
S
G
S
G
A
A
S
P
T
G
Site 32
S216
P
S
G
S
G
A
A
S
P
T
G
S
A
V
D
Site 33
T218
G
S
G
A
A
S
P
T
G
S
A
V
D
I
R
Site 34
S220
G
A
A
S
P
T
G
S
A
V
D
I
R
A
G
Site 35
S230
D
I
R
A
G
A
I
S
A
S
G
P
E
L
Q
Site 36
S232
R
A
G
A
I
S
A
S
G
P
E
L
Q
G
A
Site 37
S256
P
G
I
K
V
G
G
S
G
V
N
V
N
A
K
Site 38
S295
A
V
E
V
Q
G
P
S
L
E
S
G
D
H
G
Site 39
S317
K
V
P
K
F
G
V
S
T
G
R
E
G
Q
T
Site 40
T324
S
T
G
R
E
G
Q
T
P
K
A
G
L
R
V
Site 41
S337
R
V
S
A
P
E
V
S
V
G
H
K
G
G
K
Site 42
S357
Q
A
P
Q
L
E
V
S
V
P
S
A
N
I
E
Site 43
S379
G
P
Q
I
T
G
P
S
L
E
G
D
L
G
L
Site 44
S400
G
H
I
G
V
D
A
S
A
P
Q
I
G
G
S
Site 45
S407
S
A
P
Q
I
G
G
S
I
T
G
P
S
V
E
Site 46
S412
G
G
S
I
T
G
P
S
V
E
V
Q
A
P
D
Site 47
S427
I
D
V
Q
G
P
G
S
K
L
N
V
P
K
M
Site 48
S442
K
V
P
K
F
S
V
S
G
A
K
G
E
E
T
Site 49
T454
E
E
T
G
I
D
V
T
L
P
T
G
E
V
T
Site 50
T490
M
K
G
T
K
V
K
T
P
E
M
I
I
Q
K
Site 51
S508
S
M
Q
D
V
D
L
S
L
G
S
P
K
L
K
Site 52
S511
D
V
D
L
S
L
G
S
P
K
L
K
G
D
I
Site 53
T545
G
S
R
V
D
I
E
T
P
N
L
E
G
T
L
Site 54
T553
P
N
L
E
G
T
L
T
G
P
R
L
G
S
P
Site 55
S559
L
T
G
P
R
L
G
S
P
S
G
K
T
G
T
Site 56
S561
G
P
R
L
G
S
P
S
G
K
T
G
T
C
R
Site 57
T566
S
P
S
G
K
T
G
T
C
R
I
S
M
S
E
Site 58
S570
K
T
G
T
C
R
I
S
M
S
E
V
D
L
N
Site 59
S572
G
T
C
R
I
S
M
S
E
V
D
L
N
V
A
Site 60
T590
V
K
G
G
V
D
V
T
L
P
R
V
E
G
K
Site 61
S613
R
G
P
K
V
D
V
S
A
P
D
V
E
A
H
Site 62
T635
M
P
K
M
K
M
P
T
F
S
T
P
G
A
K
Site 63
T638
M
K
M
P
T
F
S
T
P
G
A
K
G
E
G
Site 64
T651
E
G
P
D
V
H
M
T
L
P
K
G
D
I
S
Site 65
S658
T
L
P
K
G
D
I
S
I
S
G
P
K
V
N
Site 66
S660
P
K
G
D
I
S
I
S
G
P
K
V
N
V
E
Site 67
S691
D
V
K
L
P
D
M
S
V
K
T
P
K
I
S
Site 68
T694
L
P
D
M
S
V
K
T
P
K
I
S
M
P
D
Site 69
S698
S
V
K
T
P
K
I
S
M
P
D
V
D
L
H
Site 70
Y715
G
T
K
V
K
G
E
Y
D
V
T
V
P
K
L
Site 71
T718
V
K
G
E
Y
D
V
T
V
P
K
L
E
G
E
Site 72
T788
S
G
P
K
I
D
V
T
A
P
D
V
S
I
E
Site 73
S793
D
V
T
A
P
D
V
S
I
E
E
P
E
G
K
Site 74
S819
N
I
K
V
P
K
I
S
M
P
D
V
D
L
H
Site 75
Y836
G
P
N
V
K
G
E
Y
D
V
T
M
P
K
V
Site 76
T839
V
K
G
E
Y
D
V
T
M
P
K
V
E
S
E
Site 77
S856
V
P
D
V
E
L
K
S
A
K
M
D
I
D
V
Site 78
S909
P
K
A
D
V
D
I
S
G
P
K
V
G
V
E
Site 79
Y964
G
P
K
V
K
G
E
Y
D
M
T
V
P
K
L
Site 80
T967
V
K
G
E
Y
D
M
T
V
P
K
L
E
G
D
Site 81
S983
K
G
P
K
V
D
V
S
A
P
D
V
E
M
Q
Site 82
S1010
M
P
K
F
S
M
P
S
L
K
G
E
G
P
E
Site 83
S1030
S
K
A
N
V
D
I
S
A
P
K
V
D
T
N
Site 84
T1036
I
S
A
P
K
V
D
T
N
A
P
D
L
S
L
Site 85
S1042
D
T
N
A
P
D
L
S
L
E
G
P
E
G
K
Site 86
S1068
H
F
R
A
P
K
M
S
L
P
D
V
D
L
D
Site 87
S1123
E
G
Q
G
L
D
W
S
L
K
I
P
K
M
K
Site 88
S1170
D
I
E
A
P
D
V
S
L
E
G
P
E
G
K
Site 89
T1192
M
P
E
M
H
F
K
T
P
K
I
S
M
P
D
Site 90
S1196
H
F
K
T
P
K
I
S
M
P
D
V
D
L
H
Site 91
S1216
V
K
G
D
V
D
V
S
V
P
K
V
E
G
E
Site 92
S1263
K
M
K
M
P
K
F
S
M
P
G
F
K
G
E
Site 93
S1286
P
K
A
D
I
D
V
S
G
P
K
V
D
V
E
Site 94
S1298
D
V
E
V
P
D
V
S
L
E
G
P
E
G
K
Site 95
S1324
H
F
K
A
P
K
I
S
M
P
D
V
D
L
N
Site 96
S1344
L
K
G
D
V
D
V
S
L
P
E
V
E
G
E
Site 97
S1367
K
G
P
K
V
D
I
S
A
P
D
V
D
V
H
Site 98
S1391
K
V
K
M
P
K
F
S
M
P
G
F
K
G
E
Site 99
S1445
K
F
K
M
P
E
M
S
I
K
P
Q
K
I
S
Site 100
S1452
S
I
K
P
Q
K
I
S
I
P
D
V
G
L
H
Site 101
Y1469
G
P
K
M
K
G
D
Y
D
V
T
V
P
K
V
Site 102
T1472
M
K
G
D
Y
D
V
T
V
P
K
V
E
G
E
Site 103
S1580
N
I
Q
T
H
K
I
S
M
P
D
V
G
L
N
Site 104
T1595
L
K
A
P
K
L
K
T
D
V
D
V
S
L
P
Site 105
S1600
L
K
T
D
V
D
V
S
L
P
K
V
E
G
D
Site 106
S1654
H
F
K
A
P
K
I
S
M
P
D
V
D
L
H
Site 107
S1674
V
K
G
D
M
D
V
S
V
P
K
V
E
G
E
Site 108
S1744
P
K
A
D
I
D
V
S
G
P
S
V
D
T
D
Site 109
S1747
D
I
D
V
S
G
P
S
V
D
T
D
A
P
D
Site 110
T1750
V
S
G
P
S
V
D
T
D
A
P
D
L
D
I
Site 111
S1767
P
E
G
K
L
K
G
S
K
F
K
M
P
K
L
Site 112
S1802
L
K
G
E
I
D
A
S
V
P
E
L
E
G
D
Site 113
S1876
V
K
G
D
A
D
V
S
V
P
K
L
E
G
D
Site 114
T1885
P
K
L
E
G
D
L
T
G
P
S
V
G
V
E
Site 115
S1888
E
G
D
L
T
G
P
S
V
G
V
E
V
P
D
Site 116
S1943
V
K
G
D
V
D
V
S
V
P
K
L
E
G
D
Site 117
S2080
P
K
A
D
V
V
V
S
G
P
K
V
D
V
E
Site 118
S2138
V
K
G
D
V
D
V
S
L
P
K
L
E
G
D
Site 119
T2147
P
K
L
E
G
D
L
T
G
P
S
V
D
V
E
Site 120
S2150
E
G
D
L
T
G
P
S
V
D
V
E
V
P
D
Site 121
S2185
H
F
K
T
P
K
I
S
M
P
D
V
N
L
N
Site 122
S2275
P
K
A
D
V
D
V
S
G
P
K
V
D
V
E
Site 123
T2371
G
P
N
G
K
W
K
T
P
K
F
K
M
P
D
Site 124
S2387
H
F
K
A
P
K
I
S
M
P
D
L
D
L
H
Site 125
S2397
D
L
D
L
H
L
K
S
P
K
A
K
G
E
V
Site 126
S2423
K
G
P
H
V
D
V
S
G
P
D
I
D
I
E
Site 127
S2454
H
F
K
A
P
N
I
S
M
P
D
V
D
L
N
Site 128
S2474
I
K
G
D
V
D
V
S
V
P
E
V
E
G
K
Site 129
S2542
P
K
A
D
V
D
I
S
G
P
K
V
D
I
E
Site 130
S2580
N
I
K
A
P
K
I
S
M
P
D
F
D
L
H
Site 131
S2600
V
K
G
D
V
D
V
S
L
P
K
V
E
G
D
Site 132
S2670
P
K
A
D
I
D
V
S
G
P
K
V
D
I
E
Site 133
S2708
N
I
K
A
P
K
I
S
M
P
D
I
D
L
N
Site 134
S2775
K
I
K
M
P
K
I
S
M
P
G
F
K
G
E
Site 135
S2820
D
L
K
S
S
K
A
S
L
G
S
L
E
G
E
Site 136
S2836
H
F
K
T
P
K
I
S
M
P
D
I
D
L
N
Site 137
T2845
P
D
I
D
L
N
L
T
G
P
K
I
K
G
D
Site 138
T2856
I
K
G
D
V
D
V
T
G
P
K
V
E
G
D
Site 139
S2984
V
K
G
D
V
D
I
S
L
P
K
V
E
G
D
Site 140
S3054
P
K
A
D
L
D
V
S
G
P
K
V
D
I
D
Site 141
S3112
V
K
G
D
M
D
V
S
L
P
K
V
E
G
D
Site 142
S3182
P
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S
S
S
N
D
S
G
Site 294
S5865
K
K
S
R
L
S
S
S
S
S
N
D
S
G
N
Site 295
S5866
K
S
R
L
S
S
S
S
S
N
D
S
G
N
K
Site 296
S5867
S
R
L
S
S
S
S
S
N
D
S
G
N
K
V
Site 297
S5870
S
S
S
S
S
N
D
S
G
N
K
V
G
I
Q
Site 298
S5884
Q
L
P
E
V
E
L
S
V
S
T
K
K
E
_
Site 299
S5886
P
E
V
E
L
S
V
S
T
K
K
E
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation