PhosphoNET

           
Protein Info 
   
Short Name:  TBC1D8B
Full Name:  TBC1 domain family member 8B
Alias: 
Type:  Intracellular protein
Mass (Da):  128709
Number AA:  1120
UniProt ID:  Q0IIM8
International Prot ID: 
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005622     Uniprot OncoNet
Molecular Function:  GO:0005097     PhosphoSite+ KinaseNET
Biological Process:  GO:0032313     Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1Y25LMERSNDYFVLQRRR
Site 2Y34VLQRRRGYGEEGGGG
Site 3T43EEGGGGLTGLLVGTL
Site 4T69PFRILHQTPDSQVYL
Site 5S77PDSQVYLSIACGANR
Site 6T101LEQNIMKTLSVFDSN
Site 7S103QNIMKTLSVFDSNED
Site 8S107KTLSVFDSNEDITNF
Site 9Y162EKEKLVTYYSCSYWK
Site 10Y163KEKLVTYYSCSYWKG
Site 11Y230CSQGENHYFSMFLHI
Site 12Y250LMEQLANYAIRRLFD
Site 13T260RRLFDKETFDNDPVL
Site 14Y268FDNDPVLYNPLQITK
Site 15T274LYNPLQITKRGLENR
Site 16S284GLENRAHSEQFNAFF
Site 17S298FRLPKGESLKEVHEC
Site 18Y326KMCISENYICFASQD
Site 19S338SQDGNQCSVIIPLRE
Site 20T352EVLAIDKTNDSSKSV
Site 21S355AIDKTNDSSKSVIIS
Site 22S358KTNDSSKSVIISIKG
Site 23T367IISIKGKTAFRFHEV
Site 24S392RLRCGAASTQYHDIS
Site 25Y395CGAASTQYHDISTEL
Site 26S399STQYHDISTELAISS
Site 27T400TQYHDISTELAISSE
Site 28S405ISTELAISSESTEPS
Site 29S406STELAISSESTEPSD
Site 30S408ELAISSESTEPSDNF
Site 31T409LAISSESTEPSDNFE
Site 32S412SSESTEPSDNFEVQS
Site 33S419SDNFEVQSLTSQREC
Site 34T421NFEVQSLTSQRECSK
Site 35S422FEVQSLTSQRECSKT
Site 36S427LTSQRECSKTVNTEA
Site 37T429SQRECSKTVNTEALM
Site 38T446FHPQNLETLNSKMLK
Site 39S449QNLETLNSKMLKEKM
Site 40S460KEKMKEQSWKILFAE
Site 41S473AECGRGVSMFRTKKT
Site 42T477RGVSMFRTKKTRDLV
Site 43Y513DMATNPDYYTEVVEQ
Site 44Y514MATNPDYYTEVVEQS
Site 45T515ATNPDYYTEVVEQSL
Site 46S539IERDLRRSLPEHPAF
Site 47S548PEHPAFQSDTGISAL
Site 48T550HPAFQSDTGISALRR
Site 49T560SALRRVLTAYAYRNP
Site 50Y562LRRVLTAYAYRNPKI
Site 51Y564RVLTAYAYRNPKIGY
Site 52Y606CERMLPDYFNRRIIG
Site 53T637PQLTEHMTDMTFFSS
Site 54T640TEHMTDMTFFSSVSL
Site 55T714NRFFDNVTNKDSPLP
Site 56S718DNVTNKDSPLPSNVQ
Site 57S722NKDSPLPSNVQQGSN
Site 58S731VQQGSNVSDEKTSHT
Site 59T735SNVSDEKTSHTRVDI
Site 60T743SHTRVDITDLIRESN
Site 61S749ITDLIRESNEKYGNI
Site 62Y753IRESNEKYGNIRYED
Site 63Y758EKYGNIRYEDIHSMR
Site 64Y771MRCRNRLYVIQTLEE
Site 65S795VSQDVKLSLQELDEL
Site 66Y803LQELDELYVIFKKEL
Site 67S829VLKHHDPSLPYLEQY
Site 68Y832HHDPSLPYLEQYQID
Site 69Y836SLPYLEQYQIDCQQF
Site 70Y847CQQFRALYHLLSPWA
Site 71S851RALYHLLSPWAHSAN
Site 72S856LLSPWAHSANKDSLA
Site 73S861AHSANKDSLALWTFR
Site 74T866KDSLALWTFRLLDEN
Site 75S874FRLLDENSDCLINFK
Site 76Y891SSAIDIMYNGSFTEK
Site 77S894IDIMYNGSFTEKLKL
Site 78Y911KLHIPPAYTEVKSKD
Site 79S916PAYTEVKSKDASKGD
Site 80S920EVKSKDASKGDELSK
Site 81S926ASKGDELSKEELLYF
Site 82Y932LSKEELLYFSQLHVS
Site 83S934KEELLYFSQLHVSKP
Site 84S949ANEKEAESAKHSPEK
Site 85S953EAESAKHSPEKGKGK
Site 86Y966GKIDIQAYLSQWQDE
Site 87S990DLPRMNQSQFIQFSK
Site 88T998QFIQFSKTLYNLFHE
Site 89Y1000IQFSKTLYNLFHEDP
Site 90Y1013DPEEESLYQAIAVVT
Site 91S1035EVGRKLHSPTSSAKG
Site 92S1038RKLHSPTSSAKGFSG
Site 93S1039KLHSPTSSAKGFSGT
Site 94S1044TSSAKGFSGTVCGSG
Site 95T1046SAKGFSGTVCGSGGP
Site 96S1050FSGTVCGSGGPSEEK
Site 97S1054VCGSGGPSEEKTGSH
Site 98T1058GGPSEEKTGSHLEKD
Site 99S1060PSEEKTGSHLEKDPC
Site 100S1068HLEKDPCSFREEPQW
Site 101S1112KLENARISQLRSRTK
Site 102S1116ARISQLRSRTKM___
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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