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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
HSPA14
Full Name:
Heat shock 70 kDa protein 14
Alias:
Heat shock protein HSP60
Type:
Mass (Da):
54776
Number AA:
509
UniProt ID:
Q0VDF9
International Prot ID:
IPI00292499
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0000166
GO:0005488
GO:0005524
PhosphoSite+
KinaseNET
Biological Process:
GO:0006950
GO:0050896
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T35
N
D
A
G
D
R
V
T
P
A
V
V
A
Y
S
Site 2
S55
V
G
L
A
A
K
Q
S
R
I
R
N
I
S
N
Site 3
S61
Q
S
R
I
R
N
I
S
N
T
V
M
K
V
K
Site 4
T63
R
I
R
N
I
S
N
T
V
M
K
V
K
Q
I
Site 5
S75
K
Q
I
L
G
R
S
S
S
D
P
Q
A
Q
K
Site 6
S76
Q
I
L
G
R
S
S
S
D
P
Q
A
Q
K
Y
Site 7
Y83
S
D
P
Q
A
Q
K
Y
I
A
E
S
K
C
L
Site 8
S87
A
Q
K
Y
I
A
E
S
K
C
L
V
I
E
K
Site 9
Y100
E
K
N
G
K
L
R
Y
E
I
D
T
G
E
E
Site 10
T104
K
L
R
Y
E
I
D
T
G
E
E
T
K
F
V
Site 11
S130
K
M
K
E
T
A
H
S
V
L
G
S
D
A
N
Site 12
S186
A
Y
G
I
G
Q
D
S
P
T
G
K
S
N
I
Site 13
T188
G
I
G
Q
D
S
P
T
G
K
S
N
I
L
V
Site 14
S219
S
G
I
Y
R
V
L
S
T
N
T
D
D
N
I
Site 15
T234
G
G
A
H
F
T
E
T
L
A
Q
Y
L
A
S
Site 16
Y238
F
T
E
T
L
A
Q
Y
L
A
S
E
F
Q
R
Site 17
S246
L
A
S
E
F
Q
R
S
F
K
H
D
V
R
G
Site 18
S264
A
M
M
K
L
T
N
S
A
E
V
A
K
H
S
Site 19
S271
S
A
E
V
A
K
H
S
L
S
T
L
G
S
A
Site 20
S273
E
V
A
K
H
S
L
S
T
L
G
S
A
N
C
Site 21
S284
S
A
N
C
F
L
D
S
L
Y
E
G
Q
D
F
Site 22
Y286
N
C
F
L
D
S
L
Y
E
G
Q
D
F
D
C
Site 23
S296
Q
D
F
D
C
N
V
S
R
A
R
F
E
L
L
Site 24
S305
A
R
F
E
L
L
C
S
P
L
F
N
K
C
I
Site 25
T413
E
S
G
A
S
R
F
T
V
L
F
P
S
G
T
Site 26
T420
T
V
L
F
P
S
G
T
P
L
P
A
R
R
Q
Site 27
T429
L
P
A
R
R
Q
H
T
L
Q
A
P
G
S
I
Site 28
Y444
S
S
V
C
L
E
L
Y
E
S
D
G
K
N
S
Site 29
S446
V
C
L
E
L
Y
E
S
D
G
K
N
S
A
K
Site 30
T456
K
N
S
A
K
E
E
T
K
F
A
Q
V
V
L
Site 31
T481
R
D
I
L
A
V
L
T
M
K
R
D
G
S
L
Site 32
S487
L
T
M
K
R
D
G
S
L
H
V
T
C
T
D
Site 33
T491
R
D
G
S
L
H
V
T
C
T
D
Q
E
T
G
Site 34
T493
G
S
L
H
V
T
C
T
D
Q
E
T
G
K
C
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation