PhosphoNET

           
Protein Info 
   
Short Name:  BST1
Full Name:  ADP-ribosyl cyclase 2
Alias:  ADP-ribosyl cyclase 2; Bone marrow stromal cell antigen 1; BST-1; CADPr hydrolase 2; CD157; CD157 antigen; Cyclic ADP-ribose hydrolase 2; EC 3.2.2.5
Type:  EC 3.2.2.5; Cofactor and Vitamin Metabolism - nicotinate and nicotinamide; Hydrolase
Mass (Da):  35724
Number AA:  318
UniProt ID:  Q10588
International Prot ID:  IPI00026240
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0031225  GO:0019898  GO:0005886 Uniprot OncoNet
Molecular Function:  GO:0003953  GO:0005488   PhosphoSite+ KinaseNET
Biological Process:  GO:0006959  GO:0008152  GO:0007275 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S40RWRGEGTSAHLRDIF
Site 2S59AEYRALLSPEQRNKN
Site 3S84ALDKDPCSVLPSDYD
Site 4S88DPCSVLPSDYDLFIN
Site 5S97YDLFINLSRHSIPRD
Site 6S100FINLSRHSIPRDKSL
Site 7S106HSIPRDKSLFWENSH
Site 8S112KSLFWENSHLLVNSF
Site 9S118NSHLLVNSFADNTRR
Site 10T123VNSFADNTRRFMPLS
Site 11S130TRRFMPLSDVLYGRV
Site 12Y134MPLSDVLYGRVADFL
Site 13Y154KNDSGLDYQSCPTSE
Site 14S156DSGLDYQSCPTSEDC
Site 15S176DSFWKRASIQYSKDS
Site 16Y179WKRASIQYSKDSSGV
Site 17S180KRASIQYSKDSSGVI
Site 18S194IHVMLNGSEPTGAYP
Site 19Y200GSEPTGAYPIKGFFA
Site 20Y209IKGFFADYEIPNLQK
Site 21S237IGGPNVESCGEGSMK
Site 22Y257LKDMGFQYSCINDYR
Site 23Y263QYSCINDYRPVKLLQ
Site 24T276LQCVDHSTHPDCALK
Site 25S284HPDCALKSAAAATQR
Site 26T289LKSAAAATQRKAPSL
Site 27Y297QRKAPSLYTEQRAGL
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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