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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
KIF1A
Full Name:
Kinesin-like protein KIF1A
Alias:
ATSV; Axonal transport of synaptic vesicles; Axonal transporter of synaptic vesicles; C2orf20; HUNC-104; Kinesin family member 1A; UNC104
Type:
Cytoplasm, Nucleus, Golgi apparatus, Microtubule associated complex protein; Motor protein
Mass (Da):
191064
Number AA:
1690
UniProt ID:
Q12756
International Prot ID:
IPI00604711
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005874
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0003777
PhosphoSite+
KinaseNET
Biological Process:
GO:0008089
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S17
V
R
V
R
P
F
N
S
R
E
M
S
R
D
S
Site 2
S21
P
F
N
S
R
E
M
S
R
D
S
K
C
I
I
Site 3
S24
S
R
E
M
S
R
D
S
K
C
I
I
Q
M
S
Site 4
T35
I
Q
M
S
G
S
T
T
T
I
V
N
P
K
Q
Site 5
T46
N
P
K
Q
P
K
E
T
P
K
S
F
S
F
D
Site 6
S49
Q
P
K
E
T
P
K
S
F
S
F
D
Y
S
Y
Site 7
S51
K
E
T
P
K
S
F
S
F
D
Y
S
Y
W
S
Site 8
Y54
P
K
S
F
S
F
D
Y
S
Y
W
S
H
T
S
Site 9
S55
K
S
F
S
F
D
Y
S
Y
W
S
H
T
S
P
Site 10
Y56
S
F
S
F
D
Y
S
Y
W
S
H
T
S
P
E
Site 11
Y67
T
S
P
E
D
I
N
Y
A
S
Q
K
Q
V
Y
Site 12
S69
P
E
D
I
N
Y
A
S
Q
K
Q
V
Y
R
D
Site 13
S104
G
Q
T
G
A
G
K
S
Y
T
M
M
G
K
Q
Site 14
T106
T
G
A
G
K
S
Y
T
M
M
G
K
Q
E
K
Site 15
S128
Q
L
C
E
D
L
F
S
R
I
N
D
T
T
N
Site 16
T133
L
F
S
R
I
N
D
T
T
N
D
N
M
S
Y
Site 17
T134
F
S
R
I
N
D
T
T
N
D
N
M
S
Y
S
Site 18
S139
D
T
T
N
D
N
M
S
Y
S
V
E
V
S
Y
Site 19
S141
T
N
D
N
M
S
Y
S
V
E
V
S
Y
M
E
Site 20
Y146
S
Y
S
V
E
V
S
Y
M
E
I
Y
C
E
R
Site 21
Y150
E
V
S
Y
M
E
I
Y
C
E
R
V
R
D
L
Site 22
Y177
E
H
P
L
L
G
P
Y
V
E
D
L
S
K
L
Site 23
S182
G
P
Y
V
E
D
L
S
K
L
A
V
T
S
Y
Site 24
Y189
S
K
L
A
V
T
S
Y
N
D
I
Q
D
L
M
Site 25
S198
D
I
Q
D
L
M
D
S
G
N
K
A
R
T
V
Site 26
T204
D
S
G
N
K
A
R
T
V
A
A
T
N
M
N
Site 27
T208
K
A
R
T
V
A
A
T
N
M
N
E
T
S
S
Site 28
T213
A
A
T
N
M
N
E
T
S
S
R
S
H
A
V
Site 29
S214
A
T
N
M
N
E
T
S
S
R
S
H
A
V
F
Site 30
T234
Q
K
R
H
D
A
E
T
N
I
T
T
E
K
V
Site 31
T237
H
D
A
E
T
N
I
T
T
E
K
V
S
K
I
Site 32
S252
S
L
V
D
L
A
G
S
E
R
A
D
S
T
G
Site 33
S257
A
G
S
E
R
A
D
S
T
G
A
K
G
T
R
Site 34
T258
G
S
E
R
A
D
S
T
G
A
K
G
T
R
L
Site 35
S274
E
G
A
N
I
N
K
S
L
T
T
L
G
K
V
Site 36
S290
S
A
L
A
E
M
D
S
G
P
N
K
N
K
K
Site 37
T301
K
N
K
K
K
K
K
T
D
F
I
P
Y
R
D
Site 38
T312
P
Y
R
D
S
V
L
T
W
L
L
R
E
N
L
Site 39
Y338
L
S
P
A
D
I
N
Y
D
E
T
L
S
T
L
Site 40
T341
A
D
I
N
Y
D
E
T
L
S
T
L
R
Y
A
Site 41
T344
N
Y
D
E
T
L
S
T
L
R
Y
A
D
R
A
Site 42
Y347
E
T
L
S
T
L
R
Y
A
D
R
A
K
Q
I
Site 43
T377
R
E
L
K
D
E
V
T
R
L
R
D
L
L
Y
Site 44
Y384
T
R
L
R
D
L
L
Y
A
Q
G
L
G
D
I
Site 45
S406
V
G
M
S
P
S
S
S
L
S
A
L
S
S
R
Site 46
S408
M
S
P
S
S
S
L
S
A
L
S
S
R
A
A
Site 47
S411
S
S
S
L
S
A
L
S
S
R
A
A
S
V
S
Site 48
S412
S
S
L
S
A
L
S
S
R
A
A
S
V
S
S
Site 49
S416
A
L
S
S
R
A
A
S
V
S
S
L
H
E
R
Site 50
S418
S
S
R
A
A
S
V
S
S
L
H
E
R
I
L
Site 51
S419
S
R
A
A
S
V
S
S
L
H
E
R
I
L
F
Site 52
S430
R
I
L
F
A
P
G
S
E
E
A
I
E
R
L
Site 53
T450
I
I
A
E
L
N
E
T
W
E
E
K
L
R
R
Site 54
T458
W
E
E
K
L
R
R
T
E
A
I
R
M
E
R
Site 55
T482
A
M
R
E
D
G
G
T
L
G
V
F
S
P
K
Site 56
S487
G
G
T
L
G
V
F
S
P
K
K
T
P
H
L
Site 57
T491
G
V
F
S
P
K
K
T
P
H
L
V
N
L
N
Site 58
Y510
M
S
E
C
L
L
Y
Y
I
K
D
G
I
T
R
Site 59
S545
E
E
H
C
V
F
R
S
D
S
R
G
G
S
E
Site 60
S547
H
C
V
F
R
S
D
S
R
G
G
S
E
A
V
Site 61
S551
R
S
D
S
R
G
G
S
E
A
V
V
T
L
E
Site 62
T565
E
P
C
E
G
A
D
T
Y
V
N
G
K
K
V
Site 63
Y566
P
C
E
G
A
D
T
Y
V
N
G
K
K
V
T
Site 64
S576
G
K
K
V
T
E
P
S
I
L
R
S
G
N
R
Site 65
S580
T
E
P
S
I
L
R
S
G
N
R
I
I
M
G
Site 66
T607
A
R
Q
E
R
E
R
T
P
C
A
E
T
P
A
Site 67
T612
E
R
T
P
C
A
E
T
P
A
E
P
V
D
W
Site 68
Y649
L
Q
E
L
E
D
Q
Y
R
R
E
R
E
E
A
Site 69
Y658
R
E
R
E
E
A
T
Y
L
L
E
Q
Q
R
L
Site 70
Y667
L
E
Q
Q
R
L
D
Y
E
S
K
L
E
A
L
Site 71
S669
Q
Q
R
L
D
Y
E
S
K
L
E
A
L
Q
K
Site 72
Y682
Q
K
Q
M
D
S
R
Y
Y
P
E
V
N
E
E
Site 73
Y683
K
Q
M
D
S
R
Y
Y
P
E
V
N
E
E
E
Site 74
T700
P
E
D
E
V
Q
W
T
E
R
E
C
E
L
A
Site 75
Y717
A
F
R
K
W
K
W
Y
Q
F
T
S
L
R
D
Site 76
S740
L
K
E
A
N
A
I
S
V
E
L
K
K
K
V
Site 77
T777
E
A
A
K
D
R
E
T
R
P
F
P
R
T
I
Site 78
T783
E
T
R
P
F
P
R
T
I
V
A
V
E
V
Q
Site 79
T801
N
G
A
T
H
Y
W
T
L
E
K
L
R
Q
R
Site 80
Y816
L
D
L
M
R
E
M
Y
D
R
A
A
E
V
P
Site 81
S825
R
A
A
E
V
P
S
S
V
I
E
D
C
D
N
Site 82
T835
E
D
C
D
N
V
V
T
G
G
D
P
F
Y
D
Site 83
Y841
V
T
G
G
D
P
F
Y
D
R
F
P
W
F
R
Site 84
S874
V
H
R
V
A
I
V
S
E
K
G
E
V
K
G
Site 85
Y899
A
D
E
E
A
P
D
Y
G
S
G
V
R
Q
S
Site 86
S901
E
E
A
P
D
Y
G
S
G
V
R
Q
S
G
T
Site 87
S906
Y
G
S
G
V
R
Q
S
G
T
A
K
I
S
F
Site 88
T908
S
G
V
R
Q
S
G
T
A
K
I
S
F
D
D
Site 89
S912
Q
S
G
T
A
K
I
S
F
D
D
Q
H
F
E
Site 90
S923
Q
H
F
E
K
F
Q
S
E
S
C
P
V
V
G
Site 91
S925
F
E
K
F
Q
S
E
S
C
P
V
V
G
M
S
Site 92
S932
S
C
P
V
V
G
M
S
R
S
G
T
S
Q
E
Site 93
S934
P
V
V
G
M
S
R
S
G
T
S
Q
E
E
L
Site 94
T936
V
G
M
S
R
S
G
T
S
Q
E
E
L
R
I
Site 95
S937
G
M
S
R
S
G
T
S
Q
E
E
L
R
I
V
Site 96
S978
E
G
L
L
L
D
S
S
E
K
A
A
L
D
G
Site 97
T999
D
H
L
R
L
G
N
T
F
T
F
R
V
T
V
Site 98
T1001
L
R
L
G
N
T
F
T
F
R
V
T
V
L
Q
Site 99
T1035
R
H
D
E
A
F
S
T
E
P
L
K
N
T
G
Site 100
T1041
S
T
E
P
L
K
N
T
G
R
G
P
P
L
G
Site 101
S1094
P
L
C
K
D
V
L
S
P
L
R
P
S
R
R
Site 102
S1099
V
L
S
P
L
R
P
S
R
R
H
F
P
R
V
Site 103
S1110
F
P
R
V
M
P
L
S
K
P
V
P
A
T
K
Site 104
T1116
L
S
K
P
V
P
A
T
K
L
S
T
L
T
R
Site 105
S1119
P
V
P
A
T
K
L
S
T
L
T
R
P
C
P
Site 106
Y1133
P
G
P
C
H
C
K
Y
D
L
L
V
Y
F
E
Site 107
Y1150
E
L
E
A
N
G
D
Y
I
P
A
V
V
D
H
Site 108
T1178
Q
G
I
Q
R
R
I
T
V
T
L
L
H
E
T
Site 109
T1180
I
Q
R
R
I
T
V
T
L
L
H
E
T
G
S
Site 110
S1187
T
L
L
H
E
T
G
S
H
I
R
W
K
E
V
Site 111
T1205
V
V
G
R
I
R
N
T
P
E
T
D
E
S
L
Site 112
T1208
R
I
R
N
T
P
E
T
D
E
S
L
I
D
P
Site 113
S1211
N
T
P
E
T
D
E
S
L
I
D
P
N
I
L
Site 114
Y1227
L
N
I
L
S
S
G
Y
I
H
P
A
Q
D
D
Site 115
T1236
H
P
A
Q
D
D
R
T
F
Y
Q
F
E
A
A
Site 116
Y1238
A
Q
D
D
R
T
F
Y
Q
F
E
A
A
W
D
Site 117
S1246
Q
F
E
A
A
W
D
S
S
M
H
N
S
L
L
Site 118
S1247
F
E
A
A
W
D
S
S
M
H
N
S
L
L
L
Site 119
S1251
W
D
S
S
M
H
N
S
L
L
L
N
R
V
T
Site 120
T1258
S
L
L
L
N
R
V
T
P
Y
R
E
K
I
Y
Site 121
Y1265
T
P
Y
R
E
K
I
Y
M
T
L
S
A
Y
I
Site 122
T1267
Y
R
E
K
I
Y
M
T
L
S
A
Y
I
E
M
Site 123
Y1292
K
D
F
C
M
V
F
Y
S
R
D
A
K
L
P
Site 124
S1301
R
D
A
K
L
P
A
S
R
S
I
R
N
L
F
Site 125
S1303
A
K
L
P
A
S
R
S
I
R
N
L
F
G
S
Site 126
S1310
S
I
R
N
L
F
G
S
G
S
L
R
A
S
E
Site 127
S1312
R
N
L
F
G
S
G
S
L
R
A
S
E
S
N
Site 128
S1316
G
S
G
S
L
R
A
S
E
S
N
R
V
T
G
Site 129
S1318
G
S
L
R
A
S
E
S
N
R
V
T
G
V
Y
Site 130
T1322
A
S
E
S
N
R
V
T
G
V
Y
E
L
S
L
Site 131
S1337
C
H
V
A
D
A
G
S
P
G
M
Q
R
R
R
Site 132
T1350
R
R
R
R
V
L
D
T
S
V
A
Y
V
R
G
Site 133
S1351
R
R
R
V
L
D
T
S
V
A
Y
V
R
G
E
Site 134
Y1354
V
L
D
T
S
V
A
Y
V
R
G
E
E
N
L
Site 135
S1368
L
A
G
W
R
P
R
S
D
S
L
I
L
D
H
Site 136
S1370
G
W
R
P
R
S
D
S
L
I
L
D
H
Q
W
Site 137
T1391
L
L
Q
E
V
E
K
T
R
H
Y
L
L
L
R
Site 138
Y1394
E
V
E
K
T
R
H
Y
L
L
L
R
E
K
L
Site 139
T1403
L
L
R
E
K
L
E
T
A
Q
R
P
V
P
E
Site 140
S1413
R
P
V
P
E
A
L
S
P
A
F
S
E
D
S
Site 141
S1417
E
A
L
S
P
A
F
S
E
D
S
E
S
H
G
Site 142
S1420
S
P
A
F
S
E
D
S
E
S
H
G
S
S
S
Site 143
S1422
A
F
S
E
D
S
E
S
H
G
S
S
S
A
S
Site 144
S1425
E
D
S
E
S
H
G
S
S
S
A
S
S
P
L
Site 145
S1426
D
S
E
S
H
G
S
S
S
A
S
S
P
L
S
Site 146
S1427
S
E
S
H
G
S
S
S
A
S
S
P
L
S
A
Site 147
S1429
S
H
G
S
S
S
A
S
S
P
L
S
A
E
G
Site 148
S1430
H
G
S
S
S
A
S
S
P
L
S
A
E
G
R
Site 149
S1433
S
S
A
S
S
P
L
S
A
E
G
R
P
S
P
Site 150
S1439
L
S
A
E
G
R
P
S
P
L
E
A
P
N
E
Site 151
T1460
V
K
C
L
R
L
L
T
H
T
F
N
R
E
Y
Site 152
T1462
C
L
R
L
L
T
H
T
F
N
R
E
Y
T
H
Site 153
S1475
T
H
S
H
V
C
V
S
A
S
E
S
K
L
S
Site 154
S1477
S
H
V
C
V
S
A
S
E
S
K
L
S
E
M
Site 155
S1482
S
A
S
E
S
K
L
S
E
M
S
V
T
L
L
Site 156
S1485
E
S
K
L
S
E
M
S
V
T
L
L
R
D
P
Site 157
T1487
K
L
S
E
M
S
V
T
L
L
R
D
P
S
M
Site 158
S1510
T
P
S
S
T
C
P
S
L
V
E
G
R
Y
G
Site 159
T1523
Y
G
A
T
D
L
R
T
P
Q
P
C
S
R
P
Site 160
S1528
L
R
T
P
Q
P
C
S
R
P
A
S
P
E
P
Site 161
S1532
Q
P
C
S
R
P
A
S
P
E
P
E
L
L
P
Site 162
S1543
E
L
L
P
E
A
D
S
K
K
L
P
S
P
A
Site 163
S1548
A
D
S
K
K
L
P
S
P
A
R
A
T
E
T
Site 164
T1553
L
P
S
P
A
R
A
T
E
T
D
K
E
P
Q
Site 165
T1555
S
P
A
R
A
T
E
T
D
K
E
P
Q
R
L
Site 166
S1573
D
I
Q
E
I
R
V
S
P
I
V
S
K
K
G
Site 167
S1577
I
R
V
S
P
I
V
S
K
K
G
Y
L
H
F
Site 168
Y1581
P
I
V
S
K
K
G
Y
L
H
F
L
E
P
H
Site 169
Y1603
F
V
V
V
R
R
P
Y
A
Y
M
Y
N
S
D
Site 170
Y1605
V
V
R
R
P
Y
A
Y
M
Y
N
S
D
K
D
Site 171
Y1607
R
R
P
Y
A
Y
M
Y
N
S
D
K
D
T
V
Site 172
S1609
P
Y
A
Y
M
Y
N
S
D
K
D
T
V
E
R
Site 173
T1613
M
Y
N
S
D
K
D
T
V
E
R
F
V
L
N
Site 174
S1629
A
T
A
Q
V
E
Y
S
E
D
Q
Q
A
M
L
Site 175
T1638
D
Q
Q
A
M
L
K
T
P
N
T
F
A
V
C
Site 176
S1657
G
I
L
L
Q
A
A
S
D
K
D
M
H
D
W
Site 177
Y1666
K
D
M
H
D
W
L
Y
A
F
N
P
L
L
A
Site 178
T1675
F
N
P
L
L
A
G
T
I
R
S
K
L
S
R
Site 179
S1681
G
T
I
R
S
K
L
S
R
R
R
S
A
Q
M
Site 180
S1685
S
K
L
S
R
R
R
S
A
Q
M
R
V
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation