KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
SCRN1
Full Name:
Secernin-1
Alias:
Secernin 1; SES1
Type:
Uncharacterized protein
Mass (Da):
46382
Number AA:
414
UniProt ID:
Q12765
International Prot ID:
IPI00289862
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0031965
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
GO:0006887
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S28
L
V
V
F
G
K
N
S
A
R
P
R
D
E
V
Site 2
Y40
D
E
V
Q
E
V
V
Y
F
S
A
A
D
H
E
Site 3
S50
A
A
D
H
E
P
E
S
K
V
E
C
T
Y
I
Site 4
T65
S
I
D
Q
V
P
R
T
Y
A
I
M
I
S
R
Site 5
Y66
I
D
Q
V
P
R
T
Y
A
I
M
I
S
R
P
Site 6
T97
I
A
N
E
A
I
N
T
R
E
P
A
A
E
I
Site 7
T122
L
G
L
E
R
G
E
T
A
K
E
A
L
D
V
Site 8
Y143
E
H
G
Q
G
G
N
Y
F
E
D
A
N
S
C
Site 9
S152
E
D
A
N
S
C
H
S
F
Q
S
A
Y
L
I
Site 10
S206
A
E
H
P
E
L
R
S
Y
A
Q
S
Q
G
W
Site 11
Y207
E
H
P
E
L
R
S
Y
A
Q
S
Q
G
W
W
Site 12
S210
E
L
R
S
Y
A
Q
S
Q
G
W
W
T
G
E
Site 13
S223
G
E
G
E
F
N
F
S
E
V
F
S
P
V
E
Site 14
S227
F
N
F
S
E
V
F
S
P
V
E
D
H
L
D
Site 15
S241
D
C
G
A
G
K
D
S
L
E
K
Q
E
E
S
Site 16
S248
S
L
E
K
Q
E
E
S
I
T
V
Q
T
M
M
Site 17
T250
E
K
Q
E
E
S
I
T
V
Q
T
M
M
N
T
Site 18
T257
T
V
Q
T
M
M
N
T
L
R
D
K
A
S
G
Site 19
S263
N
T
L
R
D
K
A
S
G
V
C
I
D
S
E
Site 20
S287
S
V
L
P
Q
N
R
S
S
P
C
I
H
Y
F
Site 21
S288
V
L
P
Q
N
R
S
S
P
C
I
H
Y
F
T
Site 22
Y293
R
S
S
P
C
I
H
Y
F
T
G
T
P
D
P
Site 23
T295
S
P
C
I
H
Y
F
T
G
T
P
D
P
S
R
Site 24
T297
C
I
H
Y
F
T
G
T
P
D
P
S
R
S
I
Site 25
S303
G
T
P
D
P
S
R
S
I
F
K
P
F
I
F
Site 26
T320
D
V
K
L
V
P
K
T
Q
S
P
C
F
G
D
Site 27
S322
K
L
V
P
K
T
Q
S
P
C
F
G
D
D
D
Site 28
Y348
P
D
R
R
H
E
L
Y
K
A
H
E
W
A
R
Site 29
S360
W
A
R
A
I
I
E
S
D
Q
E
Q
G
R
K
Site 30
T371
Q
G
R
K
L
R
S
T
M
L
E
L
E
K
Q
Site 31
T388
E
A
M
E
E
I
L
T
S
S
E
P
L
D
P
Site 32
S389
A
M
E
E
I
L
T
S
S
E
P
L
D
P
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation