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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
KIAA0195
Full Name:
Uncharacterized protein KIAA0195
Alias:
K0195; kiaa0195; TMEM94; Transmembrane protein 94
Type:
Mass (Da):
151151
Number AA:
1356
UniProt ID:
Q12767
International Prot ID:
IPI00783211
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S13
K
H
L
G
E
P
P
S
A
L
G
L
S
T
R
Site 2
S24
L
S
T
R
K
A
L
S
V
L
K
E
Q
L
E
Site 3
T46
R
E
R
K
K
C
L
T
W
K
E
V
W
R
S
Site 4
S91
C
G
G
Q
P
A
G
S
R
G
V
G
L
V
N
Site 5
S196
A
L
R
P
G
Q
E
S
F
A
S
L
R
G
I
Site 6
S199
P
G
Q
E
S
F
A
S
L
R
G
I
K
D
D
Site 7
S221
G
D
L
F
P
P
F
S
P
P
P
S
P
R
G
Site 8
S225
P
P
F
S
P
P
P
S
P
R
G
E
V
E
R
Site 9
S236
E
V
E
R
G
P
Q
S
P
Q
Q
H
R
L
F
Site 10
T267
M
A
L
S
R
P
V
T
A
L
D
N
E
R
F
Site 11
T275
A
L
D
N
E
R
F
T
V
Q
S
V
M
L
H
Site 12
T313
G
V
T
S
W
Q
Y
T
L
L
Q
L
Q
V
N
Site 13
S350
A
R
V
L
A
Q
M
S
K
A
S
P
S
S
L
Site 14
S353
L
A
Q
M
S
K
A
S
P
S
S
L
L
A
K
Site 15
S356
M
S
K
A
S
P
S
S
L
L
A
K
F
S
E
Site 16
S362
S
S
L
L
A
K
F
S
E
D
T
L
S
S
Y
Site 17
T365
L
A
K
F
S
E
D
T
L
S
S
Y
T
E
A
Site 18
S367
K
F
S
E
D
T
L
S
S
Y
T
E
A
V
S
Site 19
S368
F
S
E
D
T
L
S
S
Y
T
E
A
V
S
S
Site 20
Y369
S
E
D
T
L
S
S
Y
T
E
A
V
S
S
Q
Site 21
T370
E
D
T
L
S
S
Y
T
E
A
V
S
S
Q
E
Site 22
S375
S
Y
T
E
A
V
S
S
Q
E
M
L
R
C
I
Site 23
S394
L
R
V
L
G
G
T
S
P
T
L
S
H
S
S
Site 24
S398
G
G
T
S
P
T
L
S
H
S
S
S
L
L
H
Site 25
S400
T
S
P
T
L
S
H
S
S
S
L
L
H
S
L
Site 26
S402
P
T
L
S
H
S
S
S
L
L
H
S
L
G
S
Site 27
S423
V
D
K
Q
G
I
L
S
W
P
N
P
S
P
E
Site 28
T431
W
P
N
P
S
P
E
T
V
L
F
F
S
G
K
Site 29
S436
P
E
T
V
L
F
F
S
G
K
V
E
P
P
H
Site 30
S444
G
K
V
E
P
P
H
S
S
H
E
D
L
T
D
Site 31
S445
K
V
E
P
P
H
S
S
H
E
D
L
T
D
G
Site 32
T450
H
S
S
H
E
D
L
T
D
G
L
S
T
R
S
Site 33
S454
E
D
L
T
D
G
L
S
T
R
S
F
C
H
P
Site 34
S457
T
D
G
L
S
T
R
S
F
C
H
P
E
P
H
Site 35
T477
L
A
G
S
L
N
N
T
L
H
L
S
N
E
Q
Site 36
S481
L
N
N
T
L
H
L
S
N
E
Q
E
R
G
D
Site 37
S501
P
K
P
P
E
P
Y
S
H
H
K
A
H
G
R
Site 38
S509
H
H
K
A
H
G
R
S
K
H
P
S
G
S
N
Site 39
S513
H
G
R
S
K
H
P
S
G
S
N
V
S
F
S
Site 40
S515
R
S
K
H
P
S
G
S
N
V
S
F
S
R
D
Site 41
S518
H
P
S
G
S
N
V
S
F
S
R
D
T
E
G
Site 42
S520
S
G
S
N
V
S
F
S
R
D
T
E
G
G
E
Site 43
T523
N
V
S
F
S
R
D
T
E
G
G
E
E
E
P
Site 44
S531
E
G
G
E
E
E
P
S
K
T
Q
P
G
M
E
Site 45
T533
G
E
E
E
P
S
K
T
Q
P
G
M
E
S
D
Site 46
S539
K
T
Q
P
G
M
E
S
D
P
Y
E
A
E
D
Site 47
Y542
P
G
M
E
S
D
P
Y
E
A
E
D
F
V
C
Site 48
S557
D
Y
H
L
E
M
L
S
L
S
Q
D
Q
Q
N
Site 49
S559
H
L
E
M
L
S
L
S
Q
D
Q
Q
N
P
S
Site 50
S566
S
Q
D
Q
Q
N
P
S
C
I
Q
F
D
D
S
Site 51
T580
S
N
W
Q
L
H
L
T
S
L
K
P
L
G
L
Site 52
S581
N
W
Q
L
H
L
T
S
L
K
P
L
G
L
N
Site 53
T640
L
A
R
L
I
G
F
T
P
G
A
K
E
L
F
Site 54
Y656
Q
E
N
H
L
A
L
Y
R
L
P
S
A
E
T
Site 55
S660
L
A
L
Y
R
L
P
S
A
E
T
M
K
E
T
Site 56
S668
A
E
T
M
K
E
T
S
L
G
R
L
S
C
V
Site 57
S673
E
T
S
L
G
R
L
S
C
V
T
K
R
R
P
Site 58
T676
L
G
R
L
S
C
V
T
K
R
R
P
P
L
S
Site 59
S683
T
K
R
R
P
P
L
S
H
M
I
S
L
F
I
Site 60
T693
I
S
L
F
I
K
D
T
T
T
S
T
E
Q
M
Site 61
T694
S
L
F
I
K
D
T
T
T
S
T
E
Q
M
L
Site 62
T697
I
K
D
T
T
T
S
T
E
Q
M
L
S
H
G
Site 63
S702
T
S
T
E
Q
M
L
S
H
G
T
A
D
V
V
Site 64
Y723
F
W
D
G
A
D
I
Y
P
L
S
G
S
D
R
Site 65
S726
G
A
D
I
Y
P
L
S
G
S
D
R
K
K
V
Site 66
S728
D
I
Y
P
L
S
G
S
D
R
K
K
V
L
D
Site 67
Y737
R
K
K
V
L
D
F
Y
Q
R
A
C
L
S
G
Site 68
Y745
Q
R
A
C
L
S
G
Y
C
S
A
F
A
Y
K
Site 69
T780
P
G
Q
S
S
I
F
T
M
C
E
L
P
S
T
Site 70
T787
T
M
C
E
L
P
S
T
I
P
I
K
Q
N
A
Site 71
S797
I
K
Q
N
A
R
R
S
S
W
S
S
D
E
G
Site 72
S798
K
Q
N
A
R
R
S
S
W
S
S
D
E
G
I
Site 73
S800
N
A
R
R
S
S
W
S
S
D
E
G
I
G
E
Site 74
S801
A
R
R
S
S
W
S
S
D
E
G
I
G
E
V
Site 75
S890
P
N
G
D
M
P
G
S
E
I
P
P
S
S
P
Site 76
S895
P
G
S
E
I
P
P
S
S
P
S
H
A
G
S
Site 77
S896
G
S
E
I
P
P
S
S
P
S
H
A
G
S
L
Site 78
S898
E
I
P
P
S
S
P
S
H
A
G
S
L
H
D
Site 79
S902
S
S
P
S
H
A
G
S
L
H
D
D
L
N
Q
Site 80
S927
L
M
E
E
E
G
H
S
D
L
I
S
F
Q
P
Site 81
S931
E
G
H
S
D
L
I
S
F
Q
P
T
D
S
D
Site 82
T935
D
L
I
S
F
Q
P
T
D
S
D
I
P
S
F
Site 83
S937
I
S
F
Q
P
T
D
S
D
I
P
S
F
L
E
Site 84
S941
P
T
D
S
D
I
P
S
F
L
E
D
S
N
R
Site 85
S946
I
P
S
F
L
E
D
S
N
R
A
K
L
P
R
Site 86
S1009
S
S
A
N
L
R
N
S
C
L
F
L
Q
S
D
Site 87
Y1025
S
I
A
L
D
P
L
Y
P
S
R
C
S
W
E
Site 88
S1027
A
L
D
P
L
Y
P
S
R
C
S
W
E
T
F
Site 89
S1030
P
L
Y
P
S
R
C
S
W
E
T
F
G
Y
A
Site 90
T1033
P
S
R
C
S
W
E
T
F
G
Y
A
T
S
I
Site 91
S1039
E
T
F
G
Y
A
T
S
I
S
M
A
Q
A
S
Site 92
S1041
F
G
Y
A
T
S
I
S
M
A
Q
A
S
D
G
Site 93
S1046
S
I
S
M
A
Q
A
S
D
G
L
S
P
L
Q
Site 94
S1050
A
Q
A
S
D
G
L
S
P
L
Q
L
S
G
Q
Site 95
S1055
G
L
S
P
L
Q
L
S
G
Q
L
N
S
L
P
Site 96
S1064
Q
L
N
S
L
P
C
S
L
T
F
R
Q
E
E
Site 97
T1066
N
S
L
P
C
S
L
T
F
R
Q
E
E
T
I
Site 98
S1074
F
R
Q
E
E
T
I
S
I
I
R
L
I
E
Q
Site 99
T1086
I
E
Q
A
R
H
A
T
Y
G
I
R
K
C
F
Site 100
S1147
L
G
K
P
P
H
S
S
I
M
S
M
A
T
G
Site 101
S1150
P
P
H
S
S
I
M
S
M
A
T
G
K
N
L
Site 102
S1159
A
T
G
K
N
L
Q
S
I
P
K
K
T
Q
H
Site 103
T1164
L
Q
S
I
P
K
K
T
Q
H
Y
F
L
L
C
Site 104
S1193
C
F
G
F
T
L
Q
S
F
C
D
S
S
R
D
Site 105
S1197
T
L
Q
S
F
C
D
S
S
R
D
R
N
L
T
Site 106
S1198
L
Q
S
F
C
D
S
S
R
D
R
N
L
T
N
Site 107
T1204
S
S
R
D
R
N
L
T
N
C
S
S
V
M
L
Site 108
S1207
D
R
N
L
T
N
C
S
S
V
M
L
P
S
N
Site 109
S1208
R
N
L
T
N
C
S
S
V
M
L
P
S
N
D
Site 110
S1213
C
S
S
V
M
L
P
S
N
D
D
R
A
P
A
Site 111
Y1338
E
I
R
V
R
V
R
Y
Q
K
R
Q
K
L
Q
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation