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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
KIAA0196
Full Name:
WASH complex subunit strumpellin
Alias:
SPG8; STRUM; Strumpellin
Type:
Mass (Da):
134290
Number AA:
UniProt ID:
Q12768
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
GO:0008219
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y51
D
R
A
D
Q
Q
K
Y
G
D
I
I
F
D
F
Site 2
S69
K
G
P
E
L
W
E
S
K
L
D
A
K
P
E
Site 3
Y105
A
F
Q
S
V
H
K
Y
I
V
D
L
N
R
Y
Site 4
Y112
Y
I
V
D
L
N
R
Y
L
D
D
L
N
E
G
Site 5
Y121
D
D
L
N
E
G
V
Y
I
Q
Q
T
L
E
T
Site 6
S168
V
R
E
R
M
L
V
S
Y
Y
R
Y
S
A
A
Site 7
Y169
R
E
R
M
L
V
S
Y
Y
R
Y
S
A
A
R
Site 8
Y172
M
L
V
S
Y
Y
R
Y
S
A
A
R
S
S
A
Site 9
S173
L
V
S
Y
Y
R
Y
S
A
A
R
S
S
A
D
Site 10
S177
Y
R
Y
S
A
A
R
S
S
A
D
S
N
M
D
Site 11
S178
R
Y
S
A
A
R
S
S
A
D
S
N
M
D
D
Site 12
S181
A
A
R
S
S
A
D
S
N
M
D
D
I
C
K
Site 13
S192
D
I
C
K
L
L
R
S
T
G
Y
S
S
Q
P
Site 14
T193
I
C
K
L
L
R
S
T
G
Y
S
S
Q
P
G
Site 15
Y195
K
L
L
R
S
T
G
Y
S
S
Q
P
G
A
K
Site 16
S196
L
L
R
S
T
G
Y
S
S
Q
P
G
A
K
R
Site 17
S197
L
R
S
T
G
Y
S
S
Q
P
G
A
K
R
P
Site 18
S205
Q
P
G
A
K
R
P
S
N
Y
P
E
S
Y
F
Site 19
Y207
G
A
K
R
P
S
N
Y
P
E
S
Y
F
Q
R
Site 20
S210
R
P
S
N
Y
P
E
S
Y
F
Q
R
V
P
I
Site 21
Y211
P
S
N
Y
P
E
S
Y
F
Q
R
V
P
I
N
Site 22
S231
M
V
I
G
R
L
R
S
D
D
I
Y
N
Q
V
Site 23
Y235
R
L
R
S
D
D
I
Y
N
Q
V
S
A
Y
P
Site 24
Y241
I
Y
N
Q
V
S
A
Y
P
L
P
E
H
R
S
Site 25
T249
P
L
P
E
H
R
S
T
A
L
A
N
Q
A
A
Site 26
T271
F
E
P
S
I
L
H
T
H
Q
A
K
M
R
E
Site 27
Y283
M
R
E
I
V
D
K
Y
F
P
D
N
W
V
I
Site 28
T317
A
K
T
A
L
N
N
T
L
D
L
S
N
V
R
Site 29
S321
L
N
N
T
L
D
L
S
N
V
R
E
Q
A
S
Site 30
Y330
V
R
E
Q
A
S
R
Y
A
T
V
S
E
R
V
Site 31
T332
E
Q
A
S
R
Y
A
T
V
S
E
R
V
H
A
Site 32
S334
A
S
R
Y
A
T
V
S
E
R
V
H
A
Q
V
Site 33
Y349
Q
Q
F
L
K
E
G
Y
L
R
E
E
M
V
L
Site 34
S383
L
M
L
H
T
A
D
S
A
C
D
P
N
N
K
Site 35
T401
Q
I
K
D
Q
I
L
T
D
S
R
Y
N
P
R
Site 36
Y405
Q
I
L
T
D
S
R
Y
N
P
R
I
L
F
Q
Site 37
T437
Q
M
L
S
E
K
Q
T
K
W
E
H
Y
K
K
Site 38
S447
E
H
Y
K
K
E
G
S
E
R
M
T
E
L
A
Site 39
T451
K
E
G
S
E
R
M
T
E
L
A
D
V
F
S
Site 40
S458
T
E
L
A
D
V
F
S
G
V
K
P
L
T
R
Site 41
T464
F
S
G
V
K
P
L
T
R
V
E
K
N
E
N
Site 42
S480
Q
A
W
F
R
E
I
S
K
Q
I
L
S
L
N
Site 43
S485
E
I
S
K
Q
I
L
S
L
N
Y
D
D
S
T
Site 44
S491
L
S
L
N
Y
D
D
S
T
A
A
G
R
K
T
Site 45
T492
S
L
N
Y
D
D
S
T
A
A
G
R
K
T
V
Site 46
S566
Q
L
I
D
S
F
T
S
I
M
Q
E
S
I
R
Site 47
S571
F
T
S
I
M
Q
E
S
I
R
V
N
P
S
M
Site 48
S577
E
S
I
R
V
N
P
S
M
V
T
K
L
R
A
Site 49
S605
L
R
I
N
Q
A
N
S
P
D
L
L
S
V
S
Site 50
S610
A
N
S
P
D
L
L
S
V
S
Q
Y
Y
S
G
Site 51
S612
S
P
D
L
L
S
V
S
Q
Y
Y
S
G
E
L
Site 52
Y614
D
L
L
S
V
S
Q
Y
Y
S
G
E
L
V
S
Site 53
S621
Y
Y
S
G
E
L
V
S
Y
V
R
K
V
L
Q
Site 54
Y664
D
K
D
K
L
R
D
Y
A
Q
L
G
P
R
Y
Site 55
Y671
Y
A
Q
L
G
P
R
Y
E
V
A
K
L
T
H
Site 56
T747
K
L
K
E
L
G
A
T
M
D
G
F
H
R
S
Site 57
Y761
S
F
E
Y
I
Q
D
Y
V
N
I
Y
G
L
K
Site 58
Y780
E
V
S
R
I
I
N
Y
N
V
E
Q
E
C
N
Site 59
T812
H
I
P
I
P
K
F
T
P
V
D
E
S
V
T
Site 60
S857
K
T
H
Q
E
V
T
S
S
R
L
F
S
E
I
Site 61
S858
T
H
Q
E
V
T
S
S
R
L
F
S
E
I
Q
Site 62
S862
V
T
S
S
R
L
F
S
E
I
Q
T
T
L
G
Site 63
T904
K
I
I
L
R
D
R
T
V
Q
D
T
L
K
T
Site 64
T908
R
D
R
T
V
Q
D
T
L
K
T
L
M
N
A
Site 65
T911
T
V
Q
D
T
L
K
T
L
M
N
A
V
S
P
Site 66
S917
K
T
L
M
N
A
V
S
P
L
K
S
I
V
A
Site 67
S921
N
A
V
S
P
L
K
S
I
V
A
N
S
N
K
Site 68
Y967
Q
I
A
N
E
L
N
Y
S
C
R
F
D
S
K
Site 69
S973
N
Y
S
C
R
F
D
S
K
H
L
A
A
A
L
Site 70
Y995
L
A
D
I
E
A
H
Y
Q
D
P
S
L
P
Y
Site 71
S999
E
A
H
Y
Q
D
P
S
L
P
Y
P
K
E
D
Site 72
Y1002
Y
Q
D
P
S
L
P
Y
P
K
E
D
N
T
L
Site 73
T1008
P
Y
P
K
E
D
N
T
L
L
Y
E
I
T
A
Site 74
Y1011
K
E
D
N
T
L
L
Y
E
I
T
A
Y
L
E
Site 75
Y1056
A
Q
L
P
K
L
Q
Y
N
K
N
L
G
M
V
Site 76
T1068
G
M
V
C
R
K
P
T
D
P
V
D
W
P
P
Site 77
S1089
T
L
L
K
Q
F
H
S
R
Y
T
E
Q
F
L
Site 78
Y1091
L
K
Q
F
H
S
R
Y
T
E
Q
F
L
A
L
Site 79
T1092
K
Q
F
H
S
R
Y
T
E
Q
F
L
A
L
I
Site 80
S1112
S
T
V
E
Q
C
T
S
Q
K
I
P
E
I
P
Site 81
T1136
L
E
D
Y
V
R
Y
T
K
L
P
R
R
V
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation