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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TBL3
Full Name:
Transducin beta-like protein 3
Alias:
WD repeat-containing protein SAZD
Type:
Mass (Da):
89035
Number AA:
808
UniProt ID:
Q12788
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T13
A
G
V
G
R
F
K
T
N
Y
A
V
E
R
K
Site 2
Y15
V
G
R
F
K
T
N
Y
A
V
E
R
K
I
E
Site 3
Y25
E
R
K
I
E
P
F
Y
K
G
G
K
A
Q
L
Site 4
T35
G
K
A
Q
L
D
Q
T
G
Q
H
L
F
C
V
Site 5
S60
A
S
G
A
V
L
R
S
L
E
Q
E
D
Q
E
Site 6
T70
Q
E
D
Q
E
D
I
T
A
F
D
L
S
P
D
Site 7
S150
G
T
H
H
F
R
G
S
P
G
V
V
H
L
V
Site 8
S181
D
A
A
I
R
V
W
S
L
Q
D
R
S
C
L
Site 9
T209
A
F
S
A
D
G
H
T
M
L
S
S
G
R
D
Site 10
S213
D
G
H
T
M
L
S
S
G
R
D
K
I
C
I
Site 11
T232
Q
S
C
Q
A
T
R
T
V
P
V
F
E
S
V
Site 12
S251
L
L
P
E
E
P
V
S
Q
L
G
V
K
S
P
Site 13
Y261
G
V
K
S
P
G
L
Y
F
L
T
A
G
D
Q
Site 14
T270
L
T
A
G
D
Q
G
T
L
R
V
W
E
A
A
Site 15
T284
A
S
G
Q
C
V
Y
T
Q
A
Q
P
P
G
P
Site 16
T296
P
G
P
G
Q
E
L
T
H
C
T
L
A
H
T
Site 17
Y319
A
D
H
N
L
L
L
Y
E
A
R
S
L
R
L
Site 18
S323
L
L
L
Y
E
A
R
S
L
R
L
Q
K
Q
F
Site 19
S348
R
F
L
G
P
E
D
S
H
V
V
V
A
S
N
Site 20
S393
R
K
G
W
L
F
A
S
C
A
K
D
Q
S
V
Site 21
S418
V
M
C
V
A
Q
G
S
G
H
T
H
S
V
G
Site 22
S423
Q
G
S
G
H
T
H
S
V
G
T
V
C
C
S
Site 23
T426
G
H
T
H
S
V
G
T
V
C
C
S
R
L
K
Site 24
S435
C
C
S
R
L
K
E
S
F
L
V
T
G
S
Q
Site 25
T445
V
T
G
S
Q
D
C
T
V
K
L
W
P
L
P
Site 26
S457
P
L
P
K
A
L
L
S
K
N
T
A
P
D
N
Site 27
T473
P
I
L
L
Q
A
Q
T
T
Q
R
C
H
D
K
Site 28
T474
I
L
L
Q
A
Q
T
T
Q
R
C
H
D
K
D
Site 29
S498
D
K
L
L
A
T
G
S
Q
D
R
T
A
K
L
Site 30
T502
A
T
G
S
Q
D
R
T
A
K
L
W
A
L
P
Site 31
T558
Q
D
F
S
C
L
K
T
F
E
G
H
D
A
S
Site 32
S580
S
R
G
T
Q
L
L
S
S
G
S
D
G
L
V
Site 33
S581
R
G
T
Q
L
L
S
S
G
S
D
G
L
V
K
Site 34
T600
K
N
N
E
C
V
R
T
L
D
A
H
E
D
K
Site 35
T622
R
L
D
D
H
A
L
T
G
A
S
D
S
R
V
Site 36
S627
A
L
T
G
A
S
D
S
R
V
I
L
W
K
D
Site 37
T636
V
I
L
W
K
D
V
T
E
A
E
Q
A
E
E
Site 38
Y666
N
L
L
H
E
K
R
Y
L
R
A
L
G
L
A
Site 39
T684
D
R
P
H
T
V
L
T
V
I
Q
A
I
R
R
Site 40
T764
L
E
A
L
L
P
Y
T
E
R
H
F
Q
R
L
Site 41
S772
E
R
H
F
Q
R
L
S
R
T
L
Q
A
A
A
Site 42
T798
P
V
P
A
A
A
P
T
P
W
E
T
H
K
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation