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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PNRC1
Full Name:
Proline-rich nuclear receptor coactivator 1
Alias:
Proline-rich protein 2;Protein B4-2
Type:
Mass (Da):
35225
Number AA:
327
UniProt ID:
Q12796
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S24
R
L
A
P
L
G
F
S
S
R
G
Y
F
G
A
Site 2
T69
G
G
D
G
P
C
L
T
P
Q
P
R
A
P
A
Site 3
T89
S
L
A
V
A
G
G
T
P
R
A
A
P
K
K
Site 4
S105
R
K
K
K
V
R
A
S
P
A
G
Q
L
P
S
Site 5
S112
S
P
A
G
Q
L
P
S
R
F
H
Q
Y
Q
Q
Site 6
Y117
L
P
S
R
F
H
Q
Y
Q
Q
H
R
P
S
L
Site 7
S123
Q
Y
Q
Q
H
R
P
S
L
E
G
G
R
S
P
Site 8
S129
P
S
L
E
G
G
R
S
P
A
T
G
P
S
G
Site 9
T132
E
G
G
R
S
P
A
T
G
P
S
G
A
Q
E
Site 10
S135
R
S
P
A
T
G
P
S
G
A
Q
E
V
P
G
Site 11
T157
S
P
A
A
A
A
G
T
E
G
A
S
P
D
L
Site 12
S161
A
A
G
T
E
G
A
S
P
D
L
A
P
L
R
Site 13
T175
R
P
A
A
P
G
Q
T
P
L
R
K
E
V
L
Site 14
S184
L
R
K
E
V
L
K
S
K
M
G
K
S
E
K
Site 15
S189
L
K
S
K
M
G
K
S
E
K
I
A
L
P
H
Site 16
Y206
L
V
H
G
I
H
L
Y
E
Q
P
K
I
N
R
Site 17
S216
P
K
I
N
R
Q
K
S
K
Y
N
L
P
L
T
Site 18
Y218
I
N
R
Q
K
S
K
Y
N
L
P
L
T
K
I
Site 19
T223
S
K
Y
N
L
P
L
T
K
I
T
S
A
K
R
Site 20
S227
L
P
L
T
K
I
T
S
A
K
R
N
E
N
N
Site 21
S239
E
N
N
F
W
Q
D
S
V
S
S
D
R
I
Q
Site 22
S241
N
F
W
Q
D
S
V
S
S
D
R
I
Q
K
Q
Site 23
S242
F
W
Q
D
S
V
S
S
D
R
I
Q
K
Q
E
Site 24
S262
N
T
E
N
I
K
N
S
H
L
K
K
S
A
F
Site 25
T271
L
K
K
S
A
F
L
T
E
V
S
Q
K
E
N
Site 26
S274
S
A
F
L
T
E
V
S
Q
K
E
N
Y
A
G
Site 27
S285
N
Y
A
G
A
K
F
S
D
P
P
S
P
S
V
Site 28
S289
A
K
F
S
D
P
P
S
P
S
V
L
P
K
P
Site 29
S291
F
S
D
P
P
S
P
S
V
L
P
K
P
P
S
Site 30
S298
S
V
L
P
K
P
P
S
H
W
M
G
S
T
V
Site 31
S303
P
P
S
H
W
M
G
S
T
V
E
N
S
N
Q
Site 32
T304
P
S
H
W
M
G
S
T
V
E
N
S
N
Q
N
Site 33
S308
M
G
S
T
V
E
N
S
N
Q
N
R
E
L
M
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation