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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
EFEMP1
Full Name:
EGF-containing fibulin-like extracellular matrix protein 1
Alias:
Extracellular protein S1-5;Fibrillin-like protein;Fibulin-3
Type:
Mass (Da):
54641
Number AA:
493
UniProt ID:
Q12805
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S17
L
T
L
A
L
V
K
S
Q
D
T
E
E
T
I
Site 2
T25
Q
D
T
E
E
T
I
T
Y
T
Q
C
T
D
G
Site 3
Y26
D
T
E
E
T
I
T
Y
T
Q
C
T
D
G
Y
Site 4
Y33
Y
T
Q
C
T
D
G
Y
E
W
D
P
V
R
Q
Site 5
S151
A
D
P
Q
R
I
P
S
N
P
S
H
R
I
Q
Site 6
S154
Q
R
I
P
S
N
P
S
H
R
I
Q
C
A
A
Site 7
Y163
R
I
Q
C
A
A
G
Y
E
Q
S
E
H
N
V
Site 8
Y205
A
C
Q
C
P
P
G
Y
Q
K
R
G
E
Q
C
Site 9
Y236
V
N
T
P
G
S
F
Y
C
Q
C
S
P
G
F
Site 10
Y250
F
Q
L
A
A
N
N
Y
T
C
V
D
I
N
E
Site 11
Y283
I
C
Q
C
N
Q
G
Y
E
L
S
S
D
R
L
Site 12
S286
C
N
Q
G
Y
E
L
S
S
D
R
L
N
C
E
Site 13
S287
N
Q
G
Y
E
L
S
S
D
R
L
N
C
E
D
Site 14
Y303
D
E
C
R
T
S
S
Y
L
C
Q
Y
Q
C
V
Site 15
Y307
T
S
S
Y
L
C
Q
Y
Q
C
V
N
E
P
G
Site 16
Y324
S
C
M
C
P
Q
G
Y
Q
V
V
R
S
R
T
Site 17
T331
Y
Q
V
V
R
S
R
T
C
Q
D
I
N
E
C
Site 18
T341
D
I
N
E
C
E
T
T
N
E
C
R
E
D
E
Site 19
Y369
R
N
P
C
Q
D
P
Y
I
L
T
P
E
N
R
Site 20
T372
C
Q
D
P
Y
I
L
T
P
E
N
R
C
V
C
Site 21
Y395
E
L
P
Q
S
I
V
Y
K
Y
M
S
I
R
S
Site 22
Y397
P
Q
S
I
V
Y
K
Y
M
S
I
R
S
D
R
Site 23
S399
S
I
V
Y
K
Y
M
S
I
R
S
D
R
S
V
Site 24
S402
Y
K
Y
M
S
I
R
S
D
R
S
V
P
S
D
Site 25
S405
M
S
I
R
S
D
R
S
V
P
S
D
I
F
Q
Site 26
S408
R
S
D
R
S
V
P
S
D
I
F
Q
I
Q
A
Site 27
T425
I
Y
A
N
T
I
N
T
F
R
I
K
S
G
N
Site 28
S430
I
N
T
F
R
I
K
S
G
N
E
N
G
E
F
Site 29
Y438
G
N
E
N
G
E
F
Y
L
R
Q
T
S
P
V
Site 30
T442
G
E
F
Y
L
R
Q
T
S
P
V
S
A
M
L
Site 31
S454
A
M
L
V
L
V
K
S
L
S
G
P
R
E
H
Site 32
S456
L
V
L
V
K
S
L
S
G
P
R
E
H
I
V
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation