KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
GRSF1
Full Name:
G-rich sequence factor 1
Alias:
G-rich RNA sequence binding factor 1; GRSF-1
Type:
RNA binding protein
Mass (Da):
53126
Number AA:
480
UniProt ID:
Q12849
International Prot ID:
IPI00478657
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
Uniprot
OncoNet
Molecular Function:
GO:0003729
PhosphoSite+
KinaseNET
Biological Process:
GO:0006378
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T25
N
C
S
S
C
R
R
T
G
A
A
C
L
P
F
Site 2
S34
A
A
C
L
P
F
Y
S
A
A
G
S
I
P
S
Site 3
S41
S
A
A
G
S
I
P
S
G
V
S
G
R
R
R
Site 4
S44
G
S
I
P
S
G
V
S
G
R
R
R
L
L
L
Site 5
S61
G
A
A
A
A
A
A
S
Q
T
R
G
L
Q
T
Site 6
T68
S
Q
T
R
G
L
Q
T
G
P
V
P
P
G
R
Site 7
S116
A
A
A
V
P
T
R
S
Y
S
Q
E
S
K
T
Site 8
Y117
A
A
V
P
T
R
S
Y
S
Q
E
S
K
T
T
Site 9
S118
A
V
P
T
R
S
Y
S
Q
E
S
K
T
T
Y
Site 10
Y125
S
Q
E
S
K
T
T
Y
L
E
D
L
P
P
P
Site 11
Y135
D
L
P
P
P
P
E
Y
E
L
A
P
S
K
L
Site 12
S140
P
E
Y
E
L
A
P
S
K
L
E
E
E
V
D
Site 13
S160
R
A
Q
G
L
P
W
S
C
T
M
E
D
V
L
Site 14
Y216
A
L
E
K
H
R
M
Y
M
G
Q
R
Y
V
E
Site 15
Y221
R
M
Y
M
G
Q
R
Y
V
E
V
Y
E
I
N
Site 16
Y225
G
Q
R
Y
V
E
V
Y
E
I
N
N
E
D
V
Site 17
S238
D
V
D
A
L
M
K
S
L
Q
V
K
S
S
P
Site 18
S243
M
K
S
L
Q
V
K
S
S
P
V
V
N
D
G
Site 19
S244
K
S
L
Q
V
K
S
S
P
V
V
N
D
G
V
Site 20
Y259
V
R
L
R
G
L
P
Y
S
C
N
E
K
D
I
Site 21
S260
R
L
R
G
L
P
Y
S
C
N
E
K
D
I
V
Site 22
Y284
D
I
T
F
V
M
D
Y
R
G
R
R
K
T
G
Site 23
T290
D
Y
R
G
R
R
K
T
G
E
A
Y
V
Q
F
Site 24
Y294
R
R
K
T
G
E
A
Y
V
Q
F
E
E
P
E
Site 25
Y318
R
E
E
I
G
N
R
Y
I
E
I
F
P
S
R
Site 26
S324
R
Y
I
E
I
F
P
S
R
R
N
E
V
R
T
Site 27
T331
S
R
R
N
E
V
R
T
H
V
G
S
Y
K
G
Site 28
S335
E
V
R
T
H
V
G
S
Y
K
G
K
K
I
A
Site 29
S343
Y
K
G
K
K
I
A
S
F
P
T
A
K
Y
I
Site 30
T370
N
E
D
I
Q
P
M
T
A
F
E
S
E
K
E
Site 31
T396
P
E
A
A
D
F
G
T
T
S
S
L
H
F
V
Site 32
S399
A
D
F
G
T
T
S
S
L
H
F
V
H
M
R
Site 33
T430
P
L
K
P
V
R
I
T
M
E
Y
S
S
S
G
Site 34
Y433
P
V
R
I
T
M
E
Y
S
S
S
G
K
A
T
Site 35
S434
V
R
I
T
M
E
Y
S
S
S
G
K
A
T
G
Site 36
S435
R
I
T
M
E
Y
S
S
S
G
K
A
T
G
E
Site 37
S436
I
T
M
E
Y
S
S
S
G
K
A
T
G
E
A
Site 38
T440
Y
S
S
S
G
K
A
T
G
E
A
D
V
H
F
Site 39
Y468
R
S
H
V
H
H
R
Y
I
E
L
F
L
N
S
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation