PhosphoNET

           
Protein Info 
   
Short Name:  NFIA
Full Name:  Nuclear factor 1 A-type
Alias:  CCAAT-box binding transcription factor; CTF; KIAA1439; NF1-A; NF-I/A; NFI-L; Nuclear factor 1/A; Nuclear factor I/A; TGGCA-binding protein
Type:  Transcription factor
Mass (Da):  55944
Number AA:  509
UniProt ID:  Q12857
International Prot ID:  IPI00029745
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005737  GO:0005634  GO:0005886 Uniprot OncoNet
Molecular Function:  GO:0003700  GO:0008134   PhosphoSite+ KinaseNET
Biological Process:  GO:0006260  GO:0006355  GO:0006350 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1Y40LQARKRKYFKKHEKR
Site 2S49KKHEKRMSKEEERAV
Site 3Y87RKDIRPEYREDFVLT
Site 4T94YREDFVLTVTGKKPP
Site 5S106KPPCCVLSNPDQKGK
Site 6S144FKGIPLESTDGERLV
Site 7S153DGERLVKSPQCSNPG
Site 8S157LVKSPQCSNPGLCVQ
Site 9S188YFVHAADSSQSESPS
Site 10S189FVHAADSSQSESPSQ
Site 11S191HAADSSQSESPSQPS
Site 12S193ADSSQSESPSQPSDA
Site 13S195SSQSESPSQPSDADI
Site 14S232VTELVRVSQTPIAAG
Site 15T240QTPIAAGTGPNFSLS
Site 16S245AGTGPNFSLSDLESS
Site 17S247TGPNFSLSDLESSSY
Site 18S251FSLSDLESSSYYSMS
Site 19S252SLSDLESSSYYSMSP
Site 20S253LSDLESSSYYSMSPG
Site 21Y254SDLESSSYYSMSPGA
Site 22Y255DLESSSYYSMSPGAM
Site 23S256LESSSYYSMSPGAMR
Site 24S258SSSYYSMSPGAMRRS
Site 25S265SPGAMRRSLPSTSST
Site 26S268AMRRSLPSTSSTSST
Site 27T269MRRSLPSTSSTSSTK
Site 28S270RRSLPSTSSTSSTKR
Site 29S271RSLPSTSSTSSTKRL
Site 30T272SLPSTSSTSSTKRLK
Site 31S273LPSTSSTSSTKRLKS
Site 32S274PSTSSTSSTKRLKSV
Site 33T275STSSTSSTKRLKSVE
Site 34S280SSTKRLKSVEDEMDS
Site 35S287SVEDEMDSPGEEPFY
Site 36Y294SPGEEPFYTGQGRSP
Site 37T295PGEEPFYTGQGRSPG
Site 38S300FYTGQGRSPGSGSQS
Site 39S303GQGRSPGSGSQSSGW
Site 40S305GRSPGSGSQSSGWHE
Site 41S307SPGSGSQSSGWHEVE
Site 42S308PGSGSQSSGWHEVEP
Site 43S319EVEPGMPSPTTLKKS
Site 44T321EPGMPSPTTLKKSEK
Site 45T322PGMPSPTTLKKSEKS
Site 46S326SPTTLKKSEKSGFSS
Site 47S329TLKKSEKSGFSSPSP
Site 48S332KSEKSGFSSPSPSQT
Site 49S333SEKSGFSSPSPSQTS
Site 50S335KSGFSSPSPSQTSSL
Site 51S337GFSSPSPSQTSSLGT
Site 52T339SSPSPSQTSSLGTAF
Site 53S341PSPSQTSSLGTAFTQ
Site 54T344SQTSSLGTAFTQHHR
Site 55T347SSLGTAFTQHHRPVI
Site 56S360VITGPRASPHATPST
Site 57T364PRASPHATPSTLHFP
Site 58S366ASPHATPSTLHFPTS
Site 59T367SPHATPSTLHFPTSP
Site 60T372PSTLHFPTSPIIQQP
Site 61S373STLHFPTSPIIQQPG
Site 62Y382IIQQPGPYFSHPAIR
Site 63S422GFLNPNGSSQGKVHN
Site 64T434VHNPFLPTPMLPPPP
Site 65T456VPLPVPDTKPPTTST
Site 66T460VPDTKPPTTSTEGGA
Site 67S469STEGGAASPTSPTYS
Site 68T471EGGAASPTSPTYSTP
Site 69S472GGAASPTSPTYSTPS
Site 70T474AASPTSPTYSTPSTS
Site 71Y475ASPTSPTYSTPSTSP
Site 72S476SPTSPTYSTPSTSPA
Site 73T477PTSPTYSTPSTSPAN
Site 74S479SPTYSTPSTSPANRF
Site 75T480PTYSTPSTSPANRFV
Site 76S481TYSTPSTSPANRFVS
Site 77S488SPANRFVSVGPRDPS
Site 78S495SVGPRDPSFVNIPQQ
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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