PhosphoNET

           
Protein Info 
   
Short Name:  COX10
Full Name:  Protoheme IX farnesyltransferase, mitochondrial
Alias:  COX10 homologue, cytochrome c oxidase assembly protein, heme A: farnesyltransferase (yeast); Cytochrome c oxidase assembly protein; Cytochrome c oxidase assembly protein (heme A: farnesyltransferase); Cytochrome c oxidase subunit X; EC 2.5.1.-; Heme A: farnesyltransferase; Heme A:farnesyltransferase; Heme O synthase;
Type:  Transferase, Energy Metabolism group, Oxidative phosphorylation family, Metabolism of Cofactors and Vitamins group, Porphyrin metabolism family
Mass (Da):  48882
Number AA:  443
UniProt ID:  Q12887
International Prot ID:  IPI00290099
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0016021  GO:0031966   Uniprot OncoNet
Molecular Function:  GO:0008495     PhosphoSite+ KinaseNET
Biological Process:  GO:0048034  GO:0006784  GO:0006123 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S4____MAASPHTLSSR
Site 2T14TLSSRLLTGCVGGSV
Site 3Y23CVGGSVWYLERRTIQ
Site 4T28VWYLERRTIQDSPHK
Site 5S32ERRTIQDSPHKFLHL
Site 6Y60FSFLKRMYVTQLNRS
Site 7S81PKPEPVASPFLEKTS
Site 8T87ASPFLEKTSSGQAKA
Site 9S89PFLEKTSSGQAKAEI
Site 10Y97GQAKAEIYEMRPLSP
Site 11S103IYEMRPLSPPSLSLS
Site 12S106MRPLSPPSLSLSRKP
Site 13S108PLSPPSLSLSRKPNE
Site 14S110SPPSLSLSRKPNEKE
Site 15S125LIELEPDSVIEDSID
Site 16S130PDSVIEDSIDVGKET
Site 17Y151KEMKLQVYDLPGILA
Site 18S281YTPLKRISIANTWVG
Site 19Y337SWGLREDYSRGGYCM
Site 20Y342EDYSRGGYCMMSVTH
Site 21Y400SYLGFRFYVDADRRS
Site 22S407YVDADRRSSRRLFFC
Site 23S408VDADRRSSRRLFFCS
Site 24S433MLTCKRPSGGGDAGP
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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