KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
BFSP1
Full Name:
Filensin
Alias:
Beaded filament structural protein 1; Beaded filament structural protein 1, filensin; CP115; CP94; Lens fiber cell beaded-filament structural protein CP 115; Lens intermediate filament-like heavy; LIFL-H
Type:
Cytoskeletal protein
Mass (Da):
74526
Number AA:
665
UniProt ID:
Q12934
International Prot ID:
IPI00030282
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005882
GO:0016020
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0005200
GO:0005212
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S5
_
_
_
M
Y
R
R
S
Y
V
F
Q
T
R
K
Site 2
S94
A
L
A
R
Q
V
E
S
N
R
Q
R
V
R
D
Site 3
T114
A
R
L
E
R
Q
G
T
E
A
Q
R
A
L
D
Site 4
S125
R
A
L
D
E
F
R
S
K
Y
E
N
E
C
E
Site 5
Y127
L
D
E
F
R
S
K
Y
E
N
E
C
E
C
Q
Site 6
S170
Q
F
L
Q
D
D
I
S
A
A
K
D
R
H
K
Site 7
S201
I
H
T
T
P
P
A
S
I
V
T
S
G
M
R
Site 8
S205
P
P
A
S
I
V
T
S
G
M
R
E
E
K
L
Site 9
T214
M
R
E
E
K
L
L
T
E
R
E
V
A
A
L
Site 10
Y267
Y
D
D
E
I
Q
L
Y
N
E
Q
I
E
T
L
Site 11
T273
L
Y
N
E
Q
I
E
T
L
R
K
E
I
E
E
Site 12
T281
L
R
K
E
I
E
E
T
E
R
V
L
E
K
S
Site 13
S288
T
E
R
V
L
E
K
S
S
Y
D
C
R
Q
L
Site 14
Y290
R
V
L
E
K
S
S
Y
D
C
R
Q
L
A
V
Site 15
Y309
L
K
N
E
L
D
R
Y
H
R
I
I
E
I
E
Site 16
T321
E
I
E
G
N
R
L
T
S
A
F
I
E
T
P
Site 17
S339
F
T
Q
S
H
G
V
S
L
S
T
G
S
G
G
Site 18
S341
Q
S
H
G
V
S
L
S
T
G
S
G
G
K
D
Site 19
T350
G
S
G
G
K
D
L
T
R
A
L
Q
D
I
T
Site 20
T357
T
R
A
L
Q
D
I
T
A
A
K
P
R
Q
K
Site 21
T378
P
R
R
K
E
I
I
T
K
D
K
T
N
G
A
Site 22
T382
E
I
I
T
K
D
K
T
N
G
A
L
E
D
A
Site 23
T397
P
L
K
G
L
E
D
T
K
L
V
Q
V
V
L
Site 24
S408
Q
V
V
L
K
E
E
S
E
S
K
F
E
S
E
Site 25
S410
V
L
K
E
E
S
E
S
K
F
E
S
E
S
K
Site 26
S414
E
S
E
S
K
F
E
S
E
S
K
E
V
S
P
Site 27
S416
E
S
K
F
E
S
E
S
K
E
V
S
P
L
T
Site 28
S420
E
S
E
S
K
E
V
S
P
L
T
Q
E
G
A
Site 29
T423
S
K
E
V
S
P
L
T
Q
E
G
A
P
E
D
Site 30
S438
V
P
D
G
G
Q
I
S
K
G
F
G
K
L
Y
Site 31
Y445
S
K
G
F
G
K
L
Y
R
K
V
K
E
K
V
Site 32
S454
K
V
K
E
K
V
R
S
P
K
E
P
E
T
P
Site 33
T460
R
S
P
K
E
P
E
T
P
T
E
L
Y
T
K
Site 34
T474
K
E
R
H
V
L
V
T
G
D
A
N
Y
V
D
Site 35
Y485
N
Y
V
D
P
R
F
Y
V
S
S
I
T
A
K
Site 36
S488
D
P
R
F
Y
V
S
S
I
T
A
K
G
G
V
Site 37
S513
Y
D
G
Q
V
E
P
S
P
E
S
P
K
P
P
Site 38
S516
Q
V
E
P
S
P
E
S
P
K
P
P
L
E
N
Site 39
S569
G
E
E
R
D
E
E
S
R
R
P
C
A
M
V
Site 40
T577
R
R
P
C
A
M
V
T
P
G
A
E
E
P
S
Site 41
S584
T
P
G
A
E
E
P
S
I
P
E
P
P
K
P
Site 42
T603
D
G
A
E
V
L
G
T
R
S
R
S
L
P
E
Site 43
S607
V
L
G
T
R
S
R
S
L
P
E
K
G
P
P
Site 44
S627
K
T
V
E
V
V
E
S
I
E
K
I
S
T
E
Site 45
T633
E
S
I
E
K
I
S
T
E
S
I
Q
T
Y
E
Site 46
T638
I
S
T
E
S
I
Q
T
Y
E
E
T
A
V
I
Site 47
Y639
S
T
E
S
I
Q
T
Y
E
E
T
A
V
I
V
Site 48
T653
V
E
T
M
I
G
K
T
K
S
D
K
K
K
S
Site 49
S655
T
M
I
G
K
T
K
S
D
K
K
K
S
G
E
Site 50
S660
T
K
S
D
K
K
K
S
G
E
K
S
S
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation