KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
FOXF2
Full Name:
Forkhead box protein F2
Alias:
Forkhead-related activator 2;Forkhead-related protein FKHL6;Forkhead-related transcription factor 2
Type:
Mass (Da):
45993
Number AA:
444
UniProt ID:
Q12947
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S17
A
P
L
R
R
A
C
S
P
V
P
G
A
L
Q
Site 2
T44
A
A
A
A
A
P
E
T
T
S
S
S
S
S
S
Site 3
T45
A
A
A
A
P
E
T
T
S
S
S
S
S
S
S
Site 4
S46
A
A
A
P
E
T
T
S
S
S
S
S
S
S
S
Site 5
S47
A
A
P
E
T
T
S
S
S
S
S
S
S
S
A
Site 6
S48
A
P
E
T
T
S
S
S
S
S
S
S
S
A
S
Site 7
S49
P
E
T
T
S
S
S
S
S
S
S
S
A
S
C
Site 8
S50
E
T
T
S
S
S
S
S
S
S
S
A
S
C
A
Site 9
S51
T
T
S
S
S
S
S
S
S
S
A
S
C
A
S
Site 10
S52
T
S
S
S
S
S
S
S
S
A
S
C
A
S
S
Site 11
S53
S
S
S
S
S
S
S
S
A
S
C
A
S
S
S
Site 12
S55
S
S
S
S
S
S
A
S
C
A
S
S
S
S
S
Site 13
S58
S
S
S
A
S
C
A
S
S
S
S
S
S
N
S
Site 14
S59
S
S
A
S
C
A
S
S
S
S
S
S
N
S
A
Site 15
S60
S
A
S
C
A
S
S
S
S
S
S
N
S
A
S
Site 16
S61
A
S
C
A
S
S
S
S
S
S
N
S
A
S
A
Site 17
S62
S
C
A
S
S
S
S
S
S
N
S
A
S
A
P
Site 18
S63
C
A
S
S
S
S
S
S
N
S
A
S
A
P
S
Site 19
S65
S
S
S
S
S
S
N
S
A
S
A
P
S
A
A
Site 20
S67
S
S
S
S
N
S
A
S
A
P
S
A
A
C
K
Site 21
S70
S
N
S
A
S
A
P
S
A
A
C
K
S
A
G
Site 22
S85
G
G
G
A
G
A
G
S
G
G
A
K
K
A
S
Site 23
S93
G
G
A
K
K
A
S
S
G
L
R
R
P
E
K
Site 24
Y103
R
R
P
E
K
P
P
Y
S
Y
I
A
L
I
V
Site 25
S104
R
P
E
K
P
P
Y
S
Y
I
A
L
I
V
M
Site 26
S118
M
A
I
Q
S
S
P
S
K
R
L
T
L
S
E
Site 27
T122
S
S
P
S
K
R
L
T
L
S
E
I
Y
Q
F
Site 28
S124
P
S
K
R
L
T
L
S
E
I
Y
Q
F
L
Q
Site 29
Y127
R
L
T
L
S
E
I
Y
Q
F
L
Q
A
R
F
Site 30
Y141
F
P
F
F
R
G
A
Y
Q
G
W
K
N
S
V
Site 31
S153
N
S
V
R
H
N
L
S
L
N
E
C
F
I
K
Site 32
Y173
G
R
P
G
K
G
H
Y
W
T
I
D
P
A
S
Site 33
T175
P
G
K
G
H
Y
W
T
I
D
P
A
S
E
F
Site 34
S188
E
F
M
F
E
E
G
S
F
R
R
R
P
R
G
Site 35
S232
F
D
F
Q
A
P
P
S
A
P
L
G
C
H
S
Site 36
S239
S
A
P
L
G
C
H
S
Q
G
G
Y
G
G
L
Site 37
Y243
G
C
H
S
Q
G
G
Y
G
G
L
D
M
M
P
Site 38
S261
D
A
G
A
G
A
P
S
H
A
H
P
H
H
H
Site 39
T283
M
S
P
N
P
G
S
T
Y
M
A
S
C
P
V
Site 40
Y284
S
P
N
P
G
S
T
Y
M
A
S
C
P
V
P
Site 41
S287
P
G
S
T
Y
M
A
S
C
P
V
P
A
G
P
Site 42
Y308
G
G
G
G
G
G
D
Y
G
P
D
S
S
S
S
Site 43
S312
G
G
D
Y
G
P
D
S
S
S
S
P
V
P
S
Site 44
S313
G
D
Y
G
P
D
S
S
S
S
P
V
P
S
S
Site 45
S314
D
Y
G
P
D
S
S
S
S
P
V
P
S
S
P
Site 46
S315
Y
G
P
D
S
S
S
S
P
V
P
S
S
P
A
Site 47
S319
S
S
S
S
P
V
P
S
S
P
A
M
A
S
A
Site 48
S325
P
S
S
P
A
M
A
S
A
I
E
C
H
S
P
Site 49
S331
A
S
A
I
E
C
H
S
P
Y
T
S
P
A
A
Site 50
Y333
A
I
E
C
H
S
P
Y
T
S
P
A
A
H
W
Site 51
S335
E
C
H
S
P
Y
T
S
P
A
A
H
W
S
S
Site 52
S341
T
S
P
A
A
H
W
S
S
P
G
A
S
P
Y
Site 53
S342
S
P
A
A
H
W
S
S
P
G
A
S
P
Y
L
Site 54
S346
H
W
S
S
P
G
A
S
P
Y
L
K
Q
P
P
Site 55
Y348
S
S
P
G
A
S
P
Y
L
K
Q
P
P
A
L
Site 56
T356
L
K
Q
P
P
A
L
T
P
S
S
N
P
A
A
Site 57
S358
Q
P
P
A
L
T
P
S
S
N
P
A
A
S
A
Site 58
S359
P
P
A
L
T
P
S
S
N
P
A
A
S
A
G
Site 59
S364
P
S
S
N
P
A
A
S
A
G
L
H
S
S
M
Site 60
S369
A
A
S
A
G
L
H
S
S
M
S
S
Y
S
L
Site 61
S370
A
S
A
G
L
H
S
S
M
S
S
Y
S
L
E
Site 62
S372
A
G
L
H
S
S
M
S
S
Y
S
L
E
Q
S
Site 63
S373
G
L
H
S
S
M
S
S
Y
S
L
E
Q
S
Y
Site 64
S375
H
S
S
M
S
S
Y
S
L
E
Q
S
Y
L
H
Site 65
S379
S
S
Y
S
L
E
Q
S
Y
L
H
Q
N
A
R
Site 66
S390
Q
N
A
R
E
D
L
S
V
G
L
P
R
Y
Q
Site 67
Y396
L
S
V
G
L
P
R
Y
Q
H
H
S
T
P
V
Site 68
S400
L
P
R
Y
Q
H
H
S
T
P
V
C
D
R
K
Site 69
T401
P
R
Y
Q
H
H
S
T
P
V
C
D
R
K
D
Site 70
S418
L
N
F
N
G
I
S
S
F
H
P
S
A
S
G
Site 71
S422
G
I
S
S
F
H
P
S
A
S
G
S
Y
Y
H
Site 72
S424
S
S
F
H
P
S
A
S
G
S
Y
Y
H
H
H
Site 73
Y428
P
S
A
S
G
S
Y
Y
H
H
H
H
Q
S
V
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation