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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
FOXI1
Full Name:
Forkhead box protein I1
Alias:
FKH10; FKHL10; Forkhead box I1; Forkhead-related FKHL10; Forkhead-related transcription factor 6; FREAC6; FREAC-6; Hepatocyte nuclear factor 3 forkhead 3; HFH3; HFH-3; HNF-3/fork-head 3
Type:
Mass (Da):
40973
Number AA:
378
UniProt ID:
Q12951
International Prot ID:
Isoform1 - IPI00220405
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0008301
GO:0003700
PhosphoSite+
KinaseNET
Biological Process:
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S10
S
F
D
L
P
A
P
S
P
P
R
C
S
P
Q
Site 2
S15
A
P
S
P
P
R
C
S
P
Q
F
P
S
I
G
Site 3
S20
R
C
S
P
Q
F
P
S
I
G
Q
E
P
P
E
Site 4
Y31
E
P
P
E
M
N
L
Y
Y
E
N
F
F
H
P
Site 5
Y32
P
P
E
M
N
L
Y
Y
E
N
F
F
H
P
Q
Site 6
S43
F
H
P
Q
G
V
P
S
P
Q
R
P
S
F
E
Site 7
S48
V
P
S
P
Q
R
P
S
F
E
G
G
G
E
Y
Site 8
Y55
S
F
E
G
G
G
E
Y
G
A
T
P
N
P
Y
Site 9
T58
G
G
G
E
Y
G
A
T
P
N
P
Y
L
W
F
Site 10
Y62
Y
G
A
T
P
N
P
Y
L
W
F
N
G
P
T
Site 11
T71
W
F
N
G
P
T
M
T
P
P
P
Y
L
P
G
Site 12
Y75
P
T
M
T
P
P
P
Y
L
P
G
P
N
A
S
Site 13
S82
Y
L
P
G
P
N
A
S
P
F
L
P
Q
A
Y
Site 14
Y126
M
K
L
V
R
P
P
Y
S
Y
S
A
L
I
A
Site 15
S127
K
L
V
R
P
P
Y
S
Y
S
A
L
I
A
M
Site 16
T145
G
A
P
D
K
R
L
T
L
S
Q
I
Y
Q
Y
Site 17
S147
P
D
K
R
L
T
L
S
Q
I
Y
Q
Y
V
A
Site 18
Y150
R
L
T
L
S
Q
I
Y
Q
Y
V
A
D
N
F
Site 19
Y152
T
L
S
Q
I
Y
Q
Y
V
A
D
N
F
P
F
Site 20
Y160
V
A
D
N
F
P
F
Y
N
K
S
K
A
G
W
Site 21
S170
S
K
A
G
W
Q
N
S
I
R
H
N
L
S
L
Site 22
S176
N
S
I
R
H
N
L
S
L
N
D
C
F
K
K
Site 23
Y196
D
D
P
G
K
G
N
Y
W
T
L
D
P
N
C
Site 24
S220
R
R
K
R
K
R
K
S
D
V
S
S
S
T
A
Site 25
S223
R
K
R
K
S
D
V
S
S
S
T
A
S
L
A
Site 26
S224
K
R
K
S
D
V
S
S
S
T
A
S
L
A
L
Site 27
S225
R
K
S
D
V
S
S
S
T
A
S
L
A
L
E
Site 28
S228
D
V
S
S
S
T
A
S
L
A
L
E
K
T
E
Site 29
T234
A
S
L
A
L
E
K
T
E
S
S
L
P
V
D
Site 30
S236
L
A
L
E
K
T
E
S
S
L
P
V
D
S
P
Site 31
S237
A
L
E
K
T
E
S
S
L
P
V
D
S
P
K
Site 32
S242
E
S
S
L
P
V
D
S
P
K
T
T
E
P
Q
Site 33
T245
L
P
V
D
S
P
K
T
T
E
P
Q
D
I
L
Site 34
T246
P
V
D
S
P
K
T
T
E
P
Q
D
I
L
D
Site 35
S256
Q
D
I
L
D
G
A
S
P
G
G
T
T
S
S
Site 36
T260
D
G
A
S
P
G
G
T
T
S
S
P
E
K
R
Site 37
S262
A
S
P
G
G
T
T
S
S
P
E
K
R
P
S
Site 38
S263
S
P
G
G
T
T
S
S
P
E
K
R
P
S
P
Site 39
S269
S
S
P
E
K
R
P
S
P
P
P
S
G
A
P
Site 40
S273
K
R
P
S
P
P
P
S
G
A
P
C
L
N
S
Site 41
T286
N
S
F
L
S
S
M
T
A
Y
V
S
G
G
S
Site 42
S290
S
S
M
T
A
Y
V
S
G
G
S
P
T
S
H
Site 43
S293
T
A
Y
V
S
G
G
S
P
T
S
H
P
L
V
Site 44
S296
V
S
G
G
S
P
T
S
H
P
L
V
T
P
G
Site 45
T301
P
T
S
H
P
L
V
T
P
G
L
S
P
E
P
Site 46
S305
P
L
V
T
P
G
L
S
P
E
P
S
D
K
T
Site 47
S309
P
G
L
S
P
E
P
S
D
K
T
G
Q
N
S
Site 48
T312
S
P
E
P
S
D
K
T
G
Q
N
S
L
T
F
Site 49
S316
S
D
K
T
G
Q
N
S
L
T
F
N
S
F
S
Site 50
T318
K
T
G
Q
N
S
L
T
F
N
S
F
S
P
L
Site 51
S321
Q
N
S
L
T
F
N
S
F
S
P
L
T
N
L
Site 52
S323
S
L
T
F
N
S
F
S
P
L
T
N
L
S
N
Site 53
T326
F
N
S
F
S
P
L
T
N
L
S
N
H
S
G
Site 54
S329
F
S
P
L
T
N
L
S
N
H
S
G
G
G
D
Site 55
S351
N
M
L
S
Y
G
G
S
V
L
S
Q
F
S
P
Site 56
S354
S
Y
G
G
S
V
L
S
Q
F
S
P
H
F
Y
Site 57
S357
G
S
V
L
S
Q
F
S
P
H
F
Y
N
S
V
Site 58
Y361
S
Q
F
S
P
H
F
Y
N
S
V
N
T
S
G
Site 59
S363
F
S
P
H
F
Y
N
S
V
N
T
S
G
V
L
Site 60
S367
F
Y
N
S
V
N
T
S
G
V
L
Y
P
R
E
Site 61
Y371
V
N
T
S
G
V
L
Y
P
R
E
G
T
E
V
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation