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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ABR
Full Name:
Active breakpoint cluster region-related protein
Alias:
Active BCR-related gene; MDB
Type:
Intracellular protein
Mass (Da):
97697
Number AA:
859
UniProt ID:
Q12979
International Prot ID:
IPI00030389
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005829
Uniprot
OncoNet
Molecular Function:
GO:0005096
GO:0005089
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0006915
GO:0008624
GO:0035023
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S13
H
R
G
L
P
R
L
S
W
I
D
T
L
Y
S
Site 2
T17
P
R
L
S
W
I
D
T
L
Y
S
N
F
S
Y
Site 3
Y19
L
S
W
I
D
T
L
Y
S
N
F
S
Y
G
T
Site 4
Y24
T
L
Y
S
N
F
S
Y
G
T
D
E
Y
D
G
Site 5
Y29
F
S
Y
G
T
D
E
Y
D
G
E
G
N
E
E
Site 6
T46
G
P
P
E
G
S
E
T
M
P
Y
I
D
E
S
Site 7
Y49
E
G
S
E
T
M
P
Y
I
D
E
S
P
T
M
Site 8
S53
T
M
P
Y
I
D
E
S
P
T
M
S
P
Q
L
Site 9
T55
P
Y
I
D
E
S
P
T
M
S
P
Q
L
S
A
Site 10
S57
I
D
E
S
P
T
M
S
P
Q
L
S
A
R
S
Site 11
S61
P
T
M
S
P
Q
L
S
A
R
S
Q
G
R
G
Site 12
S64
S
P
Q
L
S
A
R
S
Q
G
R
G
D
G
V
Site 13
S72
Q
G
R
G
D
G
V
S
P
T
P
P
E
G
L
Site 14
T74
R
G
D
G
V
S
P
T
P
P
E
G
L
A
P
Site 15
S97
E
M
R
K
L
V
L
S
G
F
L
A
S
E
E
Site 16
Y141
Q
Q
I
E
T
I
F
Y
K
I
Q
D
I
Y
E
Site 17
Y147
F
Y
K
I
Q
D
I
Y
E
I
H
K
E
F
Y
Site 18
Y154
Y
E
I
H
K
E
F
Y
D
N
L
C
P
K
V
Site 19
Y191
Y
K
A
F
V
D
N
Y
K
V
A
L
E
T
A
Site 20
S223
K
V
K
G
P
K
D
S
K
D
S
H
T
S
V
Site 21
S226
G
P
K
D
S
K
D
S
H
T
S
V
T
M
E
Site 22
T244
Y
K
P
I
D
R
V
T
R
S
T
L
V
L
H
Site 23
S246
P
I
D
R
V
T
R
S
T
L
V
L
H
D
L
Site 24
T257
L
H
D
L
L
K
H
T
P
V
D
H
P
D
Y
Site 25
Y264
T
P
V
D
H
P
D
Y
P
L
L
Q
D
A
L
Site 26
S279
R
I
S
Q
N
F
L
S
S
I
N
E
D
I
D
Site 27
T290
E
D
I
D
P
R
R
T
A
V
T
T
P
K
G
Site 28
T293
D
P
R
R
T
A
V
T
T
P
K
G
E
T
R
Site 29
T294
P
R
R
T
A
V
T
T
P
K
G
E
T
R
Q
Site 30
S312
D
G
F
L
V
E
V
S
E
S
S
R
K
L
R
Site 31
S314
F
L
V
E
V
S
E
S
S
R
K
L
R
H
V
Site 32
Y344
S
A
G
K
H
Q
Q
Y
D
C
K
W
Y
I
P
Site 33
S359
L
A
D
L
V
F
P
S
P
E
E
S
E
A
S
Site 34
S363
V
F
P
S
P
E
E
S
E
A
S
P
Q
V
H
Site 35
S366
S
P
E
E
S
E
A
S
P
Q
V
H
P
F
P
Site 36
S385
E
D
M
K
M
K
I
S
A
L
K
S
E
I
Q
Site 37
S389
M
K
I
S
A
L
K
S
E
I
Q
K
E
K
A
Site 38
S436
I
H
N
R
N
G
K
S
Y
L
F
L
L
S
S
Site 39
Y437
H
N
R
N
G
K
S
Y
L
F
L
L
S
S
D
Site 40
S442
K
S
Y
L
F
L
L
S
S
D
Y
E
R
S
E
Site 41
S443
S
Y
L
F
L
L
S
S
D
Y
E
R
S
E
W
Site 42
Y445
L
F
L
L
S
S
D
Y
E
R
S
E
W
R
E
Site 43
S448
L
S
S
D
Y
E
R
S
E
W
R
E
A
I
Q
Site 44
S499
S
N
K
D
D
D
E
S
P
G
L
Y
G
F
L
Site 45
S519
S
A
K
G
F
K
Q
S
A
N
L
Y
C
T
L
Site 46
Y523
F
K
Q
S
A
N
L
Y
C
T
L
E
V
D
S
Site 47
T525
Q
S
A
N
L
Y
C
T
L
E
V
D
S
F
G
Site 48
Y533
L
E
V
D
S
F
G
Y
F
V
S
K
A
K
T
Site 49
S536
D
S
F
G
Y
F
V
S
K
A
K
T
R
V
F
Site 50
T546
K
T
R
V
F
R
D
T
A
E
P
K
W
D
E
Site 51
S564
I
E
L
E
G
S
Q
S
L
R
I
L
C
Y
E
Site 52
Y570
Q
S
L
R
I
L
C
Y
E
K
C
Y
D
K
T
Site 53
T602
Q
I
Q
L
D
P
Q
T
V
E
T
K
N
W
H
Site 54
S623
N
G
I
K
V
E
F
S
M
K
F
T
S
R
D
Site 55
T627
V
E
F
S
M
K
F
T
S
R
D
M
S
L
K
Site 56
S628
E
F
S
M
K
F
T
S
R
D
M
S
L
K
R
Site 57
S632
K
F
T
S
R
D
M
S
L
K
R
T
P
S
K
Site 58
T636
R
D
M
S
L
K
R
T
P
S
K
K
Q
T
G
Site 59
S638
M
S
L
K
R
T
P
S
K
K
Q
T
G
V
F
Site 60
T642
R
T
P
S
K
K
Q
T
G
V
F
G
V
K
I
Site 61
S650
G
V
F
G
V
K
I
S
V
V
T
K
R
E
R
Site 62
S658
V
V
T
K
R
E
R
S
K
V
P
Y
I
V
R
Site 63
Y662
R
E
R
S
K
V
P
Y
I
V
R
Q
C
V
E
Site 64
Y724
I
A
G
T
L
K
L
Y
F
R
E
L
P
E
P
Site 65
T734
E
L
P
E
P
L
L
T
D
R
L
Y
P
A
F
Site 66
S748
F
M
E
G
I
A
L
S
D
P
A
A
K
E
N
Site 67
S792
K
E
P
I
N
K
M
S
L
H
N
L
A
T
V
Site 68
S808
G
P
T
L
L
R
P
S
E
V
E
S
K
A
H
Site 69
S812
L
R
P
S
E
V
E
S
K
A
H
L
T
S
A
Site 70
S818
E
S
K
A
H
L
T
S
A
A
D
I
W
S
H
Site 71
S844
Y
L
Q
H
P
P
I
S
F
A
E
L
K
R
N
Site 72
T852
F
A
E
L
K
R
N
T
L
Y
F
S
T
D
V
Site 73
Y854
E
L
K
R
N
T
L
Y
F
S
T
D
V
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation