PhosphoNET

           
Protein Info 
   
Short Name:  RIZ
Full Name:  PR domain zinc finger protein 2
Alias:  GATA-3 binding protein G3B; GATA-3-binding protein G3B; HUMHOXY1; KMT8; Lysine N-methyltransferase 8; MTB-ZF; MTE-binding protein; PR domain containing 2, with ZNF domain; PR domain zinc finger protein 2: PR domain-containing protein 2: Retinoblastoma protein-interacting zinc finger protein: Zinc finger protein RIZ: MTE-binding protein: MTB-ZF: GATA-3-binding protein G3B: Lysine N-methyltransferase 8: Putative uncharacterized protein PRDM2: PR domain zinc finger protein 2: PR domain-containing protein 2: Retinoblastoma protein-interacting zinc finger protein: Zinc finger protein RIZ: MTE-binding protein: MTB-ZF: GATA-3-binding protein G3B: Lysine N-methyltransferase 8: PR domain zinc finger protein 2: PR domain-containing protein 2: Retinoblastoma protein-interacting zinc finger protein: Zinc finger protein RIZ: MTE-binding protein: MTB-ZF: GATA-3-binding protein G3B: Lysine N-methyltransferase 8: Putative uncharacterized protein PRDM2: PR domain containing 2, with ZNF domain; PRD2; PRDM2; PR-domain zinc finger protein 2; Retinoblastoma protein-binding zinc finger protein; Retinoblastoma protein-interacting zinc finger protein; Retinoblastoma protein-interacting zinc-finger protein; RIZ1; RIZ2; Zinc finger protein RIZ; Zinc-finger DNA-binding protein
Type:  EC 2.1.1.43; Transcription factor; Methyltransferase
Mass (Da):  188915
Number AA:  1718
UniProt ID:  Q13029
International Prot ID:  IPI00016780
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005794  GO:0005634   Uniprot OncoNet
Molecular Function:  GO:0018024  GO:0003700  GO:0008270 PhosphoSite+ KinaseNET
Biological Process:  GO:0006355  GO:0006350   Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S67VGDKKKRSQVKNNVY
Site 2Y74SQVKNNVYMWEVYYP
Site 3Y101EKGNWLRYVNWACSG
Site 4Y123LEINRAIYYKTLKPI
Site 5Y124EINRAIYYKTLKPIA
Site 6T126NRAIYYKTLKPIAPG
Site 7S158AIEEERASARSKRSS
Site 8S161EERASARSKRSSPKS
Site 9S164ASARSKRSSPKSRKG
Site 10S165SARSKRSSPKSRKGK
Site 11S168SKRSSPKSRKGKKKS
Site 12S175SRKGKKKSQENKNKG
Site 13T192IQDIQLKTSEPDFTS
Site 14S193QDIQLKTSEPDFTSA
Site 15T198KTSEPDFTSANMRDS
Site 16S199TSEPDFTSANMRDSA
Site 17S205TSANMRDSAEGPKED
Site 18S217KEDEEKPSASALEQP
Site 19T226SALEQPATLQEVASQ
Site 20S232ATLQEVASQEVPPEL
Site 21T241EVPPELATPAPAWEP
Site 22S298DEGEEEASMPNENSV
Site 23S304ASMPNENSVKEPEIR
Site 24T325DLLEEPKTTSEETLE
Site 25T338LEDCSEVTPAMQIPR
Site 26T370QHCERKFTTKQGLER
Site 27T385HMHIHISTVNHAFKC
Site 28Y394NHAFKCKYCGKAFGT
Site 29S421AGLKRKPSQTLQPSE
Site 30T423LKRKPSQTLQPSEDL
Site 31S427PSQTLQPSEDLADGK
Site 32S442ASGENVASKDDSSPP
Site 33S446NVASKDDSSPPSLGP
Site 34S447VASKDDSSPPSLGPD
Site 35S450KDDSSPPSLGPDCLI
Site 36S460PDCLIMNSEKASQDT
Site 37S464IMNSEKASQDTINSS
Site 38T467SEKASQDTINSSVVE
Site 39S471SQDTINSSVVEENGE
Site 40Y487KELHPCKYCKKVFGT
Site 41T496KKVFGTHTNMRRHQR
Site 42Y538AQATQNVYVPSTEPE
Site 43S541TQNVYVPSTEPEEEG
Site 44Y554EGEADDVYIMDISSN
Site 45S559DVYIMDISSNISENL
Site 46Y568NISENLNYYIDGKIQ
Site 47Y569ISENLNYYIDGKIQT
Site 48T616ITQNIKTTQVPVTED
Site 49S631LPKEPLGSTNSEAKK
Site 50S634EPLGSTNSEAKKRRT
Site 51T641SEAKKRRTASPPALP
Site 52S643AKKRRTASPPALPKI
Site 53S656KIKAETDSDPMVPSC
Site 54S678ISTTEAVSFHKEKSV
Site 55S684VSFHKEKSVYLSSKL
Site 56Y686FHKEKSVYLSSKLKQ
Site 57S688KEKSVYLSSKLKQLL
Site 58S689EKSVYLSSKLKQLLQ
Site 59T702LQTQDKLTPAGISAT
Site 60T729PASMLPVTSSRFKRR
Site 61S730ASMLPVTSSRFKRRT
Site 62S731SMLPVTSSRFKRRTS
Site 63T737SSRFKRRTSSPPSSP
Site 64S738SRFKRRTSSPPSSPQ
Site 65S739RFKRRTSSPPSSPQH
Site 66S742RRTSSPPSSPQHSPA
Site 67S743RTSSPPSSPQHSPAL
Site 68S747PPSSPQHSPALRDFG
Site 69T764SDGKAAWTDAGLTSK
Site 70S770WTDAGLTSKKSKLES
Site 71S773AGLTSKKSKLESHSD
Site 72S777SKKSKLESHSDSPAW
Site 73S779KSKLESHSDSPAWSL
Site 74S781KLESHSDSPAWSLSG
Site 75S785HSDSPAWSLSGRDER
Site 76S787DSPAWSLSGRDERET
Site 77T794SGRDERETVSPPCFD
Site 78S796RDERETVSPPCFDEY
Site 79Y803SPPCFDEYKMSKEWT
Site 80T810YKMSKEWTASSAFSS
Site 81S812MSKEWTASSAFSSVC
Site 82S813SKEWTASSAFSSVCN
Site 83S816WTASSAFSSVCNQQP
Site 84S817TASSAFSSVCNQQPL
Site 85T840KAEGTGKTPVQWESV
Site 86S846KTPVQWESVLDLSVH
Site 87S851WESVLDLSVHKKHCS
Site 88S858SVHKKHCSDSEGKEF
Site 89S860HKKHCSDSEGKEFKE
Site 90S868EGKEFKESHSVQPTC
Site 91S870KEFKESHSVQPTCSA
Site 92T874ESHSVQPTCSAVKKR
Site 93S876HSVQPTCSAVKKRKP
Site 94T884AVKKRKPTTCMLQKV
Site 95T885VKKRKPTTCMLQKVL
Site 96Y896QKVLLNEYNGIDLPV
Site 97T910VENPADGTRSPSPCK
Site 98S912NPADGTRSPSPCKSL
Site 99S914ADGTRSPSPCKSLEA
Site 100S918RSPSPCKSLEAQPDP
Site 101S931DPDLGPGSGFPAPTV
Site 102T937GSGFPAPTVESTPDV
Site 103T941PAPTVESTPDVCPSS
Site 104S947STPDVCPSSPALQTP
Site 105S948TPDVCPSSPALQTPS
Site 106T953PSSPALQTPSLSSGQ
Site 107S955SPALQTPSLSSGQLP
Site 108S957ALQTPSLSSGQLPPL
Site 109T968LPPLLIPTDPSSPPP
Site 110S971LLIPTDPSSPPPCPP
Site 111S972LIPTDPSSPPPCPPV
Site 112S999TVPLPAPSSSASPHP
Site 113S1000VPLPAPSSSASPHPC
Site 114S1001PLPAPSSSASPHPCP
Site 115S1003PAPSSSASPHPCPSP
Site 116S1009ASPHPCPSPLSNATA
Site 117S1012HPCPSPLSNATAQSP
Site 118S1024QSPLPILSPTVSPSP
Site 119T1026PLPILSPTVSPSPSP
Site 120S1028PILSPTVSPSPSPIP
Site 121S1030LSPTVSPSPSPIPPV
Site 122S1032PTVSPSPSPIPPVEP
Site 123S1042PPVEPLMSAASPGPP
Site 124S1045EPLMSAASPGPPTLS
Site 125T1050AASPGPPTLSSSSSS
Site 126S1052SPGPPTLSSSSSSSS
Site 127S1053PGPPTLSSSSSSSSS
Site 128S1054GPPTLSSSSSSSSSS
Site 129S1055PPTLSSSSSSSSSSS
Site 130S1056PTLSSSSSSSSSSSS
Site 131S1057TLSSSSSSSSSSSSF
Site 132S1058LSSSSSSSSSSSSFS
Site 133S1059SSSSSSSSSSSSFSS
Site 134S1060SSSSSSSSSSSFSSS
Site 135S1061SSSSSSSSSSFSSSS
Site 136S1062SSSSSSSSSFSSSSS
Site 137S1063SSSSSSSSFSSSSSS
Site 138S1065SSSSSSFSSSSSSSS
Site 139S1066SSSSSFSSSSSSSSP
Site 140S1067SSSSFSSSSSSSSPS
Site 141S1068SSSFSSSSSSSSPSP
Site 142S1069SSFSSSSSSSSPSPP
Site 143S1070SFSSSSSSSSPSPPP
Site 144S1071FSSSSSSSSPSPPPL
Site 145S1072SSSSSSSSPSPPPLS
Site 146S1074SSSSSSPSPPPLSAI
Site 147S1083PPLSAISSVVSSGDN
Site 148S1094SGDNLEASLPMISFK
Site 149S1099EASLPMISFKQEELE
Site 150S1118KPREEPQSAAEQDVV
Site 151S1145VCESPFLSIKDLTKH
Site 152S1154KDLTKHLSIHAEEWP
Site 153T1175VQLFKDKTDLSEHRF
Site 154S1178FKDKTDLSEHRFLLH
Site 155T1228HHEFESGTLRPQNFT
Site 156T1235TLRPQNFTDPSKAHV
Site 157S1247AHVEHMQSLPEDPLE
Site 158T1255LPEDPLETSKEEEEL
Site 159S1256PEDPLETSKEEEELN
Site 160S1265EEEELNDSSEELYTT
Site 161S1266EEELNDSSEELYTTI
Site 162Y1270NDSSEELYTTIKIMA
Site 163T1271DSSEELYTTIKIMAS
Site 164T1272SSEELYTTIKIMASG
Site 165T1282IMASGIKTKDPDVRL
Site 166Y1295RLGLNQHYPSFKPPP
Site 167S1297GLNQHYPSFKPPPFQ
Site 168T1328TTHNIPQTFTTAIRC
Site 169S1357KHILACASASDKKRY
Site 170T1365ASDKKRYTPKKNPVP
Site 171T1376NPVPLKQTVQPKNGV
Site 172S1406QPKRLNFSVELSKMS
Site 173S1410LNFSVELSKMSSNKL
Site 174S1414VELSKMSSNKLKLNA
Site 175S1439AILQKNKSAKQKADL
Site 176S1452DLKNACESSSHICPY
Site 177Y1459SSSHICPYCNREFTY
Site 178T1465PYCNREFTYIGSLNK
Site 179S1477LNKHAAFSCPKKPLS
Site 180S1484SCPKKPLSPPKKKVS
Site 181S1491SPPKKKVSHSSKKGG
Site 182S1493PKKKVSHSSKKGGHS
Site 183S1494KKKVSHSSKKGGHSS
Site 184S1500SSKKGGHSSPASSDK
Site 185S1501SKKGGHSSPASSDKN
Site 186S1504GGHSSPASSDKNSNS
Site 187S1505GHSSPASSDKNSNSN
Site 188S1509PASSDKNSNSNHRRR
Site 189S1511SSDKNSNSNHRRRTA
Site 190T1517NSNHRRRTADAEIKM
Site 191T1529IKMQSMQTPLGKTRA
Site 192T1534MQTPLGKTRARSSGP
Site 193S1538LGKTRARSSGPTQVP
Site 194S1539GKTRARSSGPTQVPL
Site 195T1542RARSSGPTQVPLPSS
Site 196S1548PTQVPLPSSSFRSKQ
Site 197S1549TQVPLPSSSFRSKQN
Site 198S1550QVPLPSSSFRSKQNV
Site 199S1553LPSSSFRSKQNVKFA
Site 200S1562QNVKFAASVKSKKPS
Site 201S1565KFAASVKSKKPSSSS
Site 202S1569SVKSKKPSSSSLRNS
Site 203S1570VKSKKPSSSSLRNSS
Site 204S1571KSKKPSSSSLRNSSP
Site 205S1572SKKPSSSSLRNSSPI
Site 206S1576SSSSLRNSSPIRMAK
Site 207S1577SSSLRNSSPIRMAKI
Site 208T1585PIRMAKITHVEGKKP
Site 209S1600KAVAKNHSAQLSSKT
Site 210S1604KNHSAQLSSKTSRSL
Site 211S1605NHSAQLSSKTSRSLH
Site 212T1607SAQLSSKTSRSLHVR
Site 213S1608AQLSSKTSRSLHVRV
Site 214S1610LSSKTSRSLHVRVQK
Site 215S1618LHVRVQKSKAVLQSK
Site 216S1624KSKAVLQSKSTLASK
Site 217S1626KAVLQSKSTLASKKR
Site 218S1630QSKSTLASKKRTDRF
Site 219T1634TLASKKRTDRFNIKS
Site 220S1641TDRFNIKSRERSGGP
Site 221S1645NIKSRERSGGPVTRS
Site 222T1650ERSGGPVTRSLQLAA
Site 223S1652SGGPVTRSLQLAAAA
Site 224S1679KQELKDFSYSLRLAS
Site 225Y1680QELKDFSYSLRLASR
Site 226S1681ELKDFSYSLRLASRC
Site 227S1686SYSLRLASRCSPPAA
Site 228Y1700APYITRQYRKVKAPA
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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