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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TRAF1
Full Name:
TNF receptor-associated factor 1
Alias:
EBI6; Epstein-Bar virus-induced 6
Type:
Mass (Da):
46164
Number AA:
416
UniProt ID:
Q13077
International Prot ID:
IPI00011549
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0006915
GO:0006461
GO:0042981
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S4
_
_
_
_
M
A
S
S
S
G
S
S
P
R
P
Site 2
S5
_
_
_
M
A
S
S
S
G
S
S
P
R
P
A
Site 3
S7
_
M
A
S
S
S
G
S
S
P
R
P
A
P
D
Site 4
S8
M
A
S
S
S
G
S
S
P
R
P
A
P
D
E
Site 5
T25
F
P
F
G
C
P
P
T
V
C
Q
D
P
K
E
Site 6
S64
C
R
G
E
D
L
Q
S
I
S
P
G
S
R
L
Site 7
S66
G
E
D
L
Q
S
I
S
P
G
S
R
L
R
T
Site 8
S69
L
Q
S
I
S
P
G
S
R
L
R
T
Q
E
K
Site 9
T73
S
P
G
S
R
L
R
T
Q
E
K
A
H
P
E
Site 10
S96
P
F
A
G
V
G
C
S
F
K
G
S
P
Q
S
Site 11
S100
V
G
C
S
F
K
G
S
P
Q
S
V
Q
E
H
Site 12
S103
S
F
K
G
S
P
Q
S
V
Q
E
H
E
V
T
Site 13
T110
S
V
Q
E
H
E
V
T
S
Q
T
S
H
L
N
Site 14
S111
V
Q
E
H
E
V
T
S
Q
T
S
H
L
N
L
Site 15
S136
R
L
G
C
G
L
E
S
G
P
M
A
L
E
Q
Site 16
S146
M
A
L
E
Q
N
L
S
D
L
Q
L
Q
A
A
Site 17
Y165
G
D
L
E
V
D
C
Y
R
A
P
C
S
E
S
Site 18
S170
D
C
Y
R
A
P
C
S
E
S
Q
E
E
L
A
Site 19
S218
S
H
L
A
L
A
T
S
I
H
Q
S
Q
L
D
Site 20
S222
L
A
T
S
I
H
Q
S
Q
L
D
R
E
R
I
Site 21
S231
L
D
R
E
R
I
L
S
L
E
Q
R
V
V
E
Site 22
T242
R
V
V
E
L
Q
Q
T
L
A
Q
K
D
Q
A
Site 23
S256
A
L
G
K
L
E
Q
S
L
R
L
M
E
E
A
Site 24
T268
E
E
A
S
F
D
G
T
F
L
W
K
I
T
N
Site 25
S283
V
T
R
R
C
H
E
S
A
C
G
R
T
V
S
Site 26
Y297
S
L
F
S
P
A
F
Y
T
A
K
Y
G
Y
K
Site 27
Y301
P
A
F
Y
T
A
K
Y
G
Y
K
L
C
L
R
Site 28
Y310
Y
K
L
C
L
R
L
Y
L
N
G
D
G
T
G
Site 29
T316
L
Y
L
N
G
D
G
T
G
K
R
T
H
L
S
Site 30
S367
D
A
F
R
P
D
L
S
S
A
S
F
Q
R
P
Site 31
S368
A
F
R
P
D
L
S
S
A
S
F
Q
R
P
Q
Site 32
S370
R
P
D
L
S
S
A
S
F
Q
R
P
Q
S
E
Site 33
S376
A
S
F
Q
R
P
Q
S
E
T
N
V
A
S
G
Site 34
T378
F
Q
R
P
Q
S
E
T
N
V
A
S
G
C
P
Site 35
S382
Q
S
E
T
N
V
A
S
G
C
P
L
F
F
P
Site 36
S391
C
P
L
F
F
P
L
S
K
L
Q
S
P
K
H
Site 37
S395
F
P
L
S
K
L
Q
S
P
K
H
A
Y
V
K
Site 38
Y400
L
Q
S
P
K
H
A
Y
V
K
D
D
T
M
F
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation