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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PLA2G7
Full Name:
Platelet-activating factor acetylhydrolase
Alias:
1-alkyl-2-acetylglycerophosphocholine esterase;2-acetyl-1-alkylglycerophosphocholine esterase;Group-VIIA phospholipase A2;LDL-associated phospholipase A2;PAF 2-acylhydrolase
Type:
Mass (Da):
50077
Number AA:
441
UniProt ID:
Q13093
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T54
A
A
A
S
F
G
Q
T
K
I
P
R
G
N
G
Site 2
Y63
I
P
R
G
N
G
P
Y
S
V
G
C
T
D
L
Site 3
S64
P
R
G
N
G
P
Y
S
V
G
C
T
D
L
M
Site 4
T75
T
D
L
M
F
D
H
T
N
K
G
T
F
L
R
Site 5
T79
F
D
H
T
N
K
G
T
F
L
R
L
Y
Y
P
Site 6
Y84
K
G
T
F
L
R
L
Y
Y
P
S
Q
D
N
D
Site 7
Y85
G
T
F
L
R
L
Y
Y
P
S
Q
D
N
D
R
Site 8
S87
F
L
R
L
Y
Y
P
S
Q
D
N
D
R
L
D
Site 9
T95
Q
D
N
D
R
L
D
T
L
W
I
P
N
K
E
Site 10
Y103
L
W
I
P
N
K
E
Y
F
W
G
L
S
K
F
Site 11
T129
R
L
L
F
G
S
M
T
T
P
A
N
W
N
S
Site 12
T130
L
L
F
G
S
M
T
T
P
A
N
W
N
S
P
Site 13
S136
T
T
P
A
N
W
N
S
P
L
R
P
G
E
K
Site 14
Y144
P
L
R
P
G
E
K
Y
P
L
V
V
F
S
H
Site 15
S183
A
V
E
H
R
D
R
S
A
S
A
T
Y
Y
F
Site 16
S185
E
H
R
D
R
S
A
S
A
T
Y
Y
F
K
D
Site 17
T187
R
D
R
S
A
S
A
T
Y
Y
F
K
D
Q
S
Site 18
Y189
R
S
A
S
A
T
Y
Y
F
K
D
Q
S
A
A
Site 19
S202
A
A
E
I
G
D
K
S
W
L
Y
L
R
T
L
Site 20
Y205
I
G
D
K
S
W
L
Y
L
R
T
L
K
Q
E
Site 21
S230
R
Q
R
A
K
E
C
S
Q
A
L
S
L
I
L
Site 22
S234
K
E
C
S
Q
A
L
S
L
I
L
D
I
D
H
Site 23
S261
D
M
E
Q
L
K
D
S
I
D
R
E
K
I
A
Site 24
S284
A
T
V
I
Q
T
L
S
E
D
Q
R
F
R
C
Site 25
Y307
F
P
L
G
D
E
V
Y
S
R
I
P
Q
P
L
Site 26
S308
P
L
G
D
E
V
Y
S
R
I
P
Q
P
L
F
Site 27
Y324
I
N
S
E
Y
F
Q
Y
P
A
N
I
I
K
M
Site 28
S336
I
K
M
K
K
C
Y
S
P
D
K
E
R
K
M
Site 29
T345
D
K
E
R
K
M
I
T
I
R
G
S
V
H
Q
Site 30
S377
K
L
K
G
D
I
D
S
N
V
A
I
D
L
S
Site 31
S388
I
D
L
S
N
K
A
S
L
A
F
L
Q
K
H
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation