KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
CHAF1B
Full Name:
Chromatin assembly factor 1 subunit B
Alias:
CAF1; CAF-1; CAF-1 subunit B; CAF1A; CAF1B; CAF1P60; CAFB; CAF-I 60 kDa subunit; CAF-Ip60; Chromatin assembly factor 1, subunit B (p60); Chromatin assembly factor I p60 subunit; Chromatin assembly factor I, p60 subunit; Chromatin assembly factor-I p60 subunit; M- phase phosphoprotein 7; M-phase phosphoprotein 7; MPHOSPH7; MPP7
Type:
DNA replication
Mass (Da):
61493
Number AA:
559
UniProt ID:
Q13112
International Prot ID:
IPI00011857
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005678
GO:0005739
GO:0005678
Uniprot
OncoNet
Molecular Function:
GO:0003682
GO:0042393
GO:0051082
PhosphoSite+
KinaseNET
Biological Process:
GO:0006281
GO:0006260
GO:0006335
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y17
W
H
N
K
E
P
V
Y
S
L
D
F
Q
H
G
Site 2
S18
H
N
K
E
P
V
Y
S
L
D
F
Q
H
G
T
Site 3
S34
G
R
I
H
R
L
A
S
A
G
V
D
T
N
V
Site 4
T39
L
A
S
A
G
V
D
T
N
V
R
I
W
K
V
Site 5
T66
L
S
N
L
A
R
H
T
K
A
V
N
V
V
R
Site 6
T120
Q
L
N
K
E
N
W
T
V
V
K
T
L
R
G
Site 7
T124
E
N
W
T
V
V
K
T
L
R
G
H
L
E
D
Site 8
Y133
R
G
H
L
E
D
V
Y
D
I
C
W
A
T
D
Site 9
S146
T
D
G
N
L
M
A
S
A
S
V
D
N
T
A
Site 10
S165
V
S
K
G
Q
K
I
S
I
F
N
E
H
K
S
Site 11
Y173
I
F
N
E
H
K
S
Y
V
Q
G
V
T
W
D
Site 12
T178
K
S
Y
V
Q
G
V
T
W
D
P
L
G
Q
Y
Site 13
Y185
T
W
D
P
L
G
Q
Y
V
A
T
L
S
C
D
Site 14
Y198
C
D
R
V
L
R
V
Y
S
I
Q
K
K
R
V
Site 15
S199
D
R
V
L
R
V
Y
S
I
Q
K
K
R
V
A
Site 16
S214
F
N
V
S
K
M
L
S
G
I
G
A
E
G
E
Site 17
S224
G
A
E
G
E
A
R
S
Y
R
M
F
H
D
D
Site 18
Y225
A
E
G
E
A
R
S
Y
R
M
F
H
D
D
S
Site 19
S235
F
H
D
D
S
M
K
S
F
F
R
R
L
S
F
Site 20
S241
K
S
F
F
R
R
L
S
F
T
P
D
G
S
L
Site 21
T265
S
G
E
N
V
M
N
T
T
Y
V
F
S
R
K
Site 22
Y267
E
N
V
M
N
T
T
Y
V
F
S
R
K
N
L
Site 23
Y330
S
E
D
S
V
L
L
Y
D
T
Q
Q
S
F
P
Site 24
T332
D
S
V
L
L
Y
D
T
Q
Q
S
F
P
F
G
Site 25
S335
L
L
Y
D
T
Q
Q
S
F
P
F
G
Y
V
S
Site 26
Y340
Q
Q
S
F
P
F
G
Y
V
S
N
I
H
Y
H
Site 27
Y346
G
Y
V
S
N
I
H
Y
H
T
L
S
D
I
S
Site 28
T348
V
S
N
I
H
Y
H
T
L
S
D
I
S
W
S
Site 29
S353
Y
H
T
L
S
D
I
S
W
S
S
D
G
A
F
Site 30
S371
S
S
T
D
G
Y
C
S
F
V
T
F
E
K
D
Site 31
T374
D
G
Y
C
S
F
V
T
F
E
K
D
E
L
G
Site 32
T394
K
P
V
L
N
M
R
T
P
D
T
A
K
K
T
Site 33
T397
L
N
M
R
T
P
D
T
A
K
K
T
K
S
Q
Site 34
S403
D
T
A
K
K
T
K
S
Q
T
H
R
G
S
S
Site 35
T405
A
K
K
T
K
S
Q
T
H
R
G
S
S
P
G
Site 36
S409
K
S
Q
T
H
R
G
S
S
P
G
P
R
P
V
Site 37
S410
S
Q
T
H
R
G
S
S
P
G
P
R
P
V
E
Site 38
T419
G
P
R
P
V
E
G
T
P
A
S
R
T
Q
D
Site 39
S422
P
V
E
G
T
P
A
S
R
T
Q
D
P
S
S
Site 40
T424
E
G
T
P
A
S
R
T
Q
D
P
S
S
P
G
Site 41
S428
A
S
R
T
Q
D
P
S
S
P
G
T
T
P
P
Site 42
S429
S
R
T
Q
D
P
S
S
P
G
T
T
P
P
Q
Site 43
T432
Q
D
P
S
S
P
G
T
T
P
P
Q
A
R
Q
Site 44
T433
D
P
S
S
P
G
T
T
P
P
Q
A
R
Q
A
Site 45
T444
A
R
Q
A
P
A
P
T
V
I
R
D
P
P
S
Site 46
S451
T
V
I
R
D
P
P
S
I
T
P
A
V
K
S
Site 47
T453
I
R
D
P
P
S
I
T
P
A
V
K
S
P
L
Site 48
S458
S
I
T
P
A
V
K
S
P
L
P
G
P
S
E
Site 49
S464
K
S
P
L
P
G
P
S
E
E
K
T
L
Q
P
Site 50
T468
P
G
P
S
E
E
K
T
L
Q
P
S
S
Q
N
Site 51
S473
E
K
T
L
Q
P
S
S
Q
N
T
K
A
H
P
Site 52
T476
L
Q
P
S
S
Q
N
T
K
A
H
P
S
R
R
Site 53
S481
Q
N
T
K
A
H
P
S
R
R
V
T
L
N
T
Site 54
T485
A
H
P
S
R
R
V
T
L
N
T
L
Q
A
W
Site 55
T488
S
R
R
V
T
L
N
T
L
Q
A
W
S
K
T
Site 56
T495
T
L
Q
A
W
S
K
T
T
P
R
R
I
N
L
Site 57
T496
L
Q
A
W
S
K
T
T
P
R
R
I
N
L
T
Site 58
T503
T
P
R
R
I
N
L
T
P
L
K
T
D
T
P
Site 59
T507
I
N
L
T
P
L
K
T
D
T
P
P
S
S
V
Site 60
T509
L
T
P
L
K
T
D
T
P
P
S
S
V
P
T
Site 61
S512
L
K
T
D
T
P
P
S
S
V
P
T
S
V
I
Site 62
S513
K
T
D
T
P
P
S
S
V
P
T
S
V
I
S
Site 63
T516
T
P
P
S
S
V
P
T
S
V
I
S
T
P
S
Site 64
S517
P
P
S
S
V
P
T
S
V
I
S
T
P
S
T
Site 65
S520
S
V
P
T
S
V
I
S
T
P
S
T
E
E
I
Site 66
T521
V
P
T
S
V
I
S
T
P
S
T
E
E
I
Q
Site 67
S523
T
S
V
I
S
T
P
S
T
E
E
I
Q
S
E
Site 68
T524
S
V
I
S
T
P
S
T
E
E
I
Q
S
E
T
Site 69
S529
P
S
T
E
E
I
Q
S
E
T
P
G
D
A
Q
Site 70
T531
T
E
E
I
Q
S
E
T
P
G
D
A
Q
G
S
Site 71
S538
T
P
G
D
A
Q
G
S
P
P
E
L
K
R
P
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation