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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TRAF3
Full Name:
TNF receptor-associated factor 3
Alias:
CAP-1;CD40 receptor-associated factor 1;CD40-binding protein;LMP1-associated protein 1
Type:
Mass (Da):
64490
Number AA:
568
UniProt ID:
Q13114
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S9
E
S
S
K
K
M
D
S
P
G
A
L
Q
T
N
Site 2
T15
D
S
P
G
A
L
Q
T
N
P
P
L
K
L
H
Site 3
T23
N
P
P
L
K
L
H
T
D
R
S
A
G
T
P
Site 4
S26
L
K
L
H
T
D
R
S
A
G
T
P
V
F
V
Site 5
T29
H
T
D
R
S
A
G
T
P
V
F
V
P
E
Q
Site 6
Y39
F
V
P
E
Q
G
G
Y
K
E
K
F
V
K
T
Site 7
T46
Y
K
E
K
F
V
K
T
V
E
D
K
Y
K
C
Site 8
Y51
V
K
T
V
E
D
K
Y
K
C
E
K
C
H
L
Site 9
S62
K
C
H
L
V
L
C
S
P
K
Q
T
E
C
G
Site 10
T66
V
L
C
S
P
K
Q
T
E
C
G
H
R
F
C
Site 11
T89
S
S
S
S
P
K
C
T
A
C
Q
E
S
I
V
Site 12
Y116
E
I
L
A
L
Q
I
Y
C
R
N
E
S
R
G
Site 13
Y172
H
V
E
K
A
C
K
Y
R
E
A
T
C
S
H
Site 14
S178
K
Y
R
E
A
T
C
S
H
C
K
S
Q
V
P
Site 15
T195
A
L
Q
K
H
E
D
T
D
C
P
C
V
V
V
Site 16
S209
V
S
C
P
H
K
C
S
V
Q
T
L
L
R
S
Site 17
T212
P
H
K
C
S
V
Q
T
L
L
R
S
E
L
S
Site 18
S216
S
V
Q
T
L
L
R
S
E
L
S
A
H
L
S
Site 19
S223
S
E
L
S
A
H
L
S
E
C
V
N
A
P
S
Site 20
S230
S
E
C
V
N
A
P
S
T
C
S
F
K
R
Y
Site 21
T231
E
C
V
N
A
P
S
T
C
S
F
K
R
Y
G
Site 22
Y237
S
T
C
S
F
K
R
Y
G
C
V
F
Q
G
T
Site 23
S267
V
N
L
L
K
E
W
S
N
S
L
E
K
K
V
Site 24
S269
L
L
K
E
W
S
N
S
L
E
K
K
V
S
L
Site 25
S275
N
S
L
E
K
K
V
S
L
L
Q
N
E
S
V
Site 26
S281
V
S
L
L
Q
N
E
S
V
E
K
N
K
S
I
Site 27
S287
E
S
V
E
K
N
K
S
I
Q
S
L
H
N
Q
Site 28
S290
E
K
N
K
S
I
Q
S
L
H
N
Q
I
C
S
Site 29
S297
S
L
H
N
Q
I
C
S
F
E
I
E
I
E
R
Site 30
S314
E
M
L
R
N
N
E
S
K
I
L
H
L
Q
R
Site 31
S325
H
L
Q
R
V
I
D
S
Q
A
E
K
L
K
E
Site 32
S349
Q
N
W
E
E
A
D
S
M
K
S
S
V
E
S
Site 33
S352
E
E
A
D
S
M
K
S
S
V
E
S
L
Q
N
Site 34
S353
E
A
D
S
M
K
S
S
V
E
S
L
Q
N
R
Site 35
S356
S
M
K
S
S
V
E
S
L
Q
N
R
V
T
E
Site 36
T362
E
S
L
Q
N
R
V
T
E
L
E
S
V
D
K
Site 37
S370
E
L
E
S
V
D
K
S
A
G
Q
V
A
R
N
Site 38
T378
A
G
Q
V
A
R
N
T
G
L
L
E
S
Q
L
Site 39
S383
R
N
T
G
L
L
E
S
Q
L
S
R
H
D
Q
Site 40
S386
G
L
L
E
S
Q
L
S
R
H
D
Q
M
L
S
Site 41
S393
S
R
H
D
Q
M
L
S
V
H
D
I
R
L
A
Site 42
Y425
L
I
W
K
I
R
D
Y
K
R
R
K
Q
E
A
Site 43
T437
Q
E
A
V
M
G
K
T
L
S
L
Y
S
Q
P
Site 44
Y441
M
G
K
T
L
S
L
Y
S
Q
P
F
Y
T
G
Site 45
S442
G
K
T
L
S
L
Y
S
Q
P
F
Y
T
G
Y
Site 46
Y446
S
L
Y
S
Q
P
F
Y
T
G
Y
F
G
Y
K
Site 47
Y449
S
Q
P
F
Y
T
G
Y
F
G
Y
K
M
C
A
Site 48
Y459
Y
K
M
C
A
R
V
Y
L
N
G
D
G
M
G
Site 49
S503
L
M
L
M
D
Q
G
S
S
R
R
H
L
G
D
Site 50
S504
M
L
M
D
Q
G
S
S
R
R
H
L
G
D
A
Site 51
S518
A
F
K
P
D
P
N
S
S
S
F
K
K
P
T
Site 52
S519
F
K
P
D
P
N
S
S
S
F
K
K
P
T
G
Site 53
S520
K
P
D
P
N
S
S
S
F
K
K
P
T
G
E
Site 54
Y548
T
V
L
E
N
G
T
Y
I
K
D
D
T
I
F
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation