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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
MTAP
Full Name:
S-methyl-5'-thioadenosine phosphorylase
Alias:
5'-methylthioadenosine phosphorylase; c86fus; methylthioadenosine phosphorylase; MSAP; MTA phosphorylase; MTAPase; S-methyl-5-thioadenosine phosphorylase
Type:
Phosphorylase; Transferase; EC 2.4.2.28; Amino Acid Metabolism - cysteine and methionine
Mass (Da):
31236
Number AA:
283
UniProt ID:
Q13126
International Prot ID:
IPI00011876
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
Uniprot
OncoNet
Molecular Function:
GO:0017061
GO:0004645
PhosphoSite+
KinaseNET
Biological Process:
GO:0009116
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T5
_
_
_
M
A
S
G
T
T
T
T
A
V
K
I
Site 2
T6
_
_
M
A
S
G
T
T
T
T
A
V
K
I
G
Site 3
T7
_
M
A
S
G
T
T
T
T
A
V
K
I
G
I
Site 4
T8
M
A
S
G
T
T
T
T
A
V
K
I
G
I
I
Site 5
Y33
L
E
G
R
T
E
K
Y
V
D
T
P
F
G
K
Site 6
T36
R
T
E
K
Y
V
D
T
P
F
G
K
P
S
D
Site 7
T66
A
R
H
G
R
Q
H
T
I
M
P
S
K
V
N
Site 8
T118
D
Q
F
I
D
R
T
T
M
R
P
Q
S
F
Y
Site 9
S123
R
T
T
M
R
P
Q
S
F
Y
D
G
S
H
S
Site 10
Y125
T
M
R
P
Q
S
F
Y
D
G
S
H
S
C
A
Site 11
S128
P
Q
S
F
Y
D
G
S
H
S
C
A
R
G
V
Site 12
T148
A
E
P
F
C
P
K
T
R
E
V
L
I
E
T
Site 13
S178
T
I
E
G
P
R
F
S
S
R
A
E
S
F
M
Site 14
S179
I
E
G
P
R
F
S
S
R
A
E
S
F
M
F
Site 15
S183
R
F
S
S
R
A
E
S
F
M
F
R
T
W
G
Site 16
T188
A
E
S
F
M
F
R
T
W
G
A
D
V
I
N
Site 17
Y221
S
I
A
M
A
T
D
Y
D
C
W
K
E
H
E
Site 18
S232
K
E
H
E
E
A
V
S
V
D
R
V
L
K
T
Site 19
T239
S
V
D
R
V
L
K
T
L
K
E
N
A
N
K
Site 20
S249
E
N
A
N
K
A
K
S
L
L
L
T
T
I
P
Site 21
S260
T
T
I
P
Q
I
G
S
T
E
W
S
E
T
L
Site 22
S264
Q
I
G
S
T
E
W
S
E
T
L
H
N
L
K
Site 23
T266
G
S
T
E
W
S
E
T
L
H
N
L
K
N
M
Site 24
S277
L
K
N
M
A
Q
F
S
V
L
L
P
R
H
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation