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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CALCOCO2
Full Name:
Calcium-binding and coiled-coil domain-containing protein 2
Alias:
CACO2; Calcium binding and coiled-coil domain 2; NDP52; Nuclear domain 10 protein
Type:
Calcium-binding protein
Mass (Da):
52254
Number AA:
446
UniProt ID:
Q13137
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005794
GO:0005856
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0042803
PhosphoSite+
KinaseNET
Biological Process:
GO:0034341
GO:0016032
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T10
E
T
I
K
D
P
P
T
S
A
V
L
L
D
H
Site 2
S11
T
I
K
D
P
P
T
S
A
V
L
L
D
H
C
Site 3
S85
P
I
D
L
N
N
K
S
A
K
Q
Q
E
V
Q
Site 4
Y96
Q
E
V
Q
F
K
A
Y
Y
L
P
K
D
D
E
Site 5
Y97
E
V
Q
F
K
A
Y
Y
L
P
K
D
D
E
Y
Site 6
Y104
Y
L
P
K
D
D
E
Y
Y
Q
F
C
Y
V
D
Site 7
Y105
L
P
K
D
D
E
Y
Y
Q
F
C
Y
V
D
E
Site 8
Y109
D
E
Y
Y
Q
F
C
Y
V
D
E
D
G
V
V
Site 9
S120
D
G
V
V
R
G
A
S
I
P
F
Q
F
R
P
Site 10
S162
E
N
Q
E
L
K
D
S
C
I
S
L
Q
K
Q
Site 11
S165
E
L
K
D
S
C
I
S
L
Q
K
Q
N
S
D
Site 12
S171
I
S
L
Q
K
Q
N
S
D
M
Q
A
E
L
Q
Site 13
T186
K
K
Q
E
E
L
E
T
L
Q
S
I
N
K
K
Site 14
S189
E
E
L
E
T
L
Q
S
I
N
K
K
L
E
L
Site 15
Y204
K
V
K
E
Q
K
D
Y
W
E
T
E
L
L
Q
Site 16
S221
E
Q
N
Q
K
M
S
S
E
N
E
K
M
G
I
Site 17
S238
D
Q
L
Q
A
Q
L
S
T
Q
E
K
E
M
E
Site 18
T255
V
Q
G
D
Q
D
K
T
E
Q
L
E
Q
L
K
Site 19
S271
E
N
D
H
L
F
L
S
L
T
E
Q
R
K
D
Site 20
T273
D
H
L
F
L
S
L
T
E
Q
R
K
D
Q
K
Site 21
S311
M
D
E
N
F
D
L
S
K
R
L
S
E
N
E
Site 22
S315
F
D
L
S
K
R
L
S
E
N
E
I
I
C
N
Site 23
S343
D
L
L
K
R
E
N
S
R
L
L
S
Y
M
G
Site 24
S347
R
E
N
S
R
L
L
S
Y
M
G
L
D
F
N
Site 25
S355
Y
M
G
L
D
F
N
S
L
P
Y
Q
V
P
T
Site 26
Y358
L
D
F
N
S
L
P
Y
Q
V
P
T
S
D
E
Site 27
S363
L
P
Y
Q
V
P
T
S
D
E
G
G
A
R
Q
Site 28
Y376
R
Q
N
P
G
L
A
Y
G
N
P
Y
S
G
I
Site 29
Y380
G
L
A
Y
G
N
P
Y
S
G
I
Q
E
S
S
Site 30
S381
L
A
Y
G
N
P
Y
S
G
I
Q
E
S
S
S
Site 31
S386
P
Y
S
G
I
Q
E
S
S
S
P
S
P
L
S
Site 32
S387
Y
S
G
I
Q
E
S
S
S
P
S
P
L
S
I
Site 33
S388
S
G
I
Q
E
S
S
S
P
S
P
L
S
I
K
Site 34
S390
I
Q
E
S
S
S
P
S
P
L
S
I
K
K
C
Site 35
S393
S
S
S
P
S
P
L
S
I
K
K
C
P
I
C
Site 36
T409
A
D
D
I
C
D
H
T
L
E
Q
Q
Q
M
Q
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation