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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
FADD
Full Name:
Protein FADD
Alias:
FAS-associated death domain protein
Type:
Apoptosis protein
Mass (Da):
23279
Number AA:
208
UniProt ID:
Q13158
International Prot ID:
IPI00011919
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005829
GO:0044424
GO:0044444
Uniprot
OncoNet
Molecular Function:
GO:0005102
GO:0005123
GO:0005488
PhosphoSite+
KinaseNET
Biological Process:
GO:0006915
GO:0006917
GO:0007154
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S16
H
S
V
S
S
S
L
S
S
S
E
L
T
E
L
Site 2
S17
S
V
S
S
S
L
S
S
S
E
L
T
E
L
K
Site 3
S18
V
S
S
S
L
S
S
S
E
L
T
E
L
K
F
Site 4
T21
S
L
S
S
S
E
L
T
E
L
K
F
L
C
L
Site 5
S41
R
K
L
E
R
V
Q
S
G
L
D
L
F
S
M
Site 6
S47
Q
S
G
L
D
L
F
S
M
L
L
E
Q
N
D
Site 7
T60
N
D
L
E
P
G
H
T
E
L
L
R
E
L
L
Site 8
S122
L
A
R
Q
L
K
V
S
D
T
K
I
D
S
I
Site 9
T124
R
Q
L
K
V
S
D
T
K
I
D
S
I
E
D
Site 10
S128
V
S
D
T
K
I
D
S
I
E
D
R
Y
P
R
Site 11
Y133
I
D
S
I
E
D
R
Y
P
R
N
L
T
E
R
Site 12
T138
D
R
Y
P
R
N
L
T
E
R
V
R
E
S
L
Site 13
S144
L
T
E
R
V
R
E
S
L
R
I
W
K
N
T
Site 14
T151
S
L
R
I
W
K
N
T
E
K
E
N
A
T
V
Site 15
T157
N
T
E
K
E
N
A
T
V
A
H
L
V
G
A
Site 16
S190
A
R
D
L
Q
N
R
S
G
A
M
S
P
M
S
Site 17
S194
Q
N
R
S
G
A
M
S
P
M
S
W
N
S
D
Site 18
S197
S
G
A
M
S
P
M
S
W
N
S
D
A
S
T
Site 19
S200
M
S
P
M
S
W
N
S
D
A
S
T
S
E
A
Site 20
S203
M
S
W
N
S
D
A
S
T
S
E
A
S
_
_
Site 21
T204
S
W
N
S
D
A
S
T
S
E
A
S
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation